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1.
Mala Mahto Baidarbhi Chakraborthy Srinivas H. Gowda Harneet Kaur Gaurav Vishnoi Pramod Lali 《Indian journal of clinical biochemistry : IJCB》2012,27(3):284-289
The implications of subclinical hypothyroidism (SCH) are many amongst which the most important is progression to overt hypothyroidism. Other debatable aspects are its association with cardiovascular risk, neuromuscular and psychiatric dysfunction, increased predisposition to developing metabolic syndrome and an underlying pro-inflammatory state. We aimed to study the lipid profile, lipoprotein(a) [Lp(a)] and hsCRP levels and insulin resistance in a group of patients with SCH in a referral hospital and see if any significant differences exist between them and euthyroids. This is a case–control study where the selection of controls and cases was based on the thyroid profile. Subjects were selected on their visit to clinical biochemistry lab for thyroid function tests. 33 euthyroids were taken as controls (Group I) and 38 patients comprising of subclinical hypothyroids were grouped as cases (Group II). Serum thyroid stimulating hormone (TSH) was in the range of 0.5–5.0 mIU/L for euthyroids and for subclinical hypothyroids the concentration of TSH was more than 5 mIU/L. The concentration of tri-iodothyronine (T3) and thyroxine (T4) were in normal reference range in both the groups. Individual lipid profile parameters failed to show a significant p value between cases and controls. The LDL/HDL ratio was highly significant (p value < 0.0001) and hsCRP was also statistically between the two groups (p value = 0.0054). Lp(a) and insulin resistance did not differ significantly. SCH is a common disorder that frequently progresses to overt hypothyroidism. This study underlines the importance of LDL/HDL ratio rather than measurement of individual lipid profile parameters in bringing to light the dyslipidemic state associated with SCH. Moreover the use of hsCRP to detect an underlying pro-inflammatory state in SCH can also be emphasized. 相似文献
2.
过程导向的职业教育意味着什么? 总被引：3，自引：0，他引：3
为了促进职业教育更好地适应企业的需要、促进技术和组织结构的迅速更新，新颁布的《职业教育条例》提出了“针对过程”开展职业教育的要求。从此，《职业教育条例》只描述相关企业所共有的任务，而具体的教育内容则由职业教育企业自行确定。本文阐述了“过程针对性”对开展职业教育的影响，提出了相关人员的新型任务和专门化训练的需求。 相似文献
3.
In this article, an inclusive treatment package for children with ADHD, The ADHD Classroom Kit (Kit), is described. Components of the Kit are categorized in three areas: consequences for appropriate behavior, consequences for inappropriate behavior, and peer-mediated interventions. The empirical rationale for each component of the Kit is discussed. Also, a case study of a 6-year-old girl (Carol) with reported disruptive behavior problems is presented as preliminary data supporting the Kit's effectiveness. An A-B-A reversal design was used in Carol's classroom. Mean frequencies of appropriate behavior were 61.3% (baseline), 78.5% (Kit), and 70.7% (reversal). In addition, mean frequencies of on-task behavior were 76.2% (baseline), 87.8% (Kit), and 82.5% (reversal). Implications for future research and practice with the Kit are addressed. © 1998 John Wiley & Sons, Inc. 相似文献
4.
Maguire S Mann M John N Ellaway B Sibert JR Kemp AM;Welsh Child Protection Systematic Review Group 《Child abuse & neglect》2006,30(7):739-751
BACKGROUND: There is a diagnostic dilemma when a child presents with rib fractures after cardiopulmonary resuscitation (CPR) where child abuse is suspected as the cause of collapse. We have performed a systematic review to establish the evidence base for the following questions: (i) Does cardiopulmonary resuscitation cause rib fractures in children? (ii) If so, what are the frequency and characteristics of these fractures that may help to distinguish them from rib fractures caused by physical abuse? METHODS: We performed a literature search of original articles, references, textbooks, and conference abstracts, published in any language from 1950 to 1 October 2005. Articles were identified from ASSIA, Caredata, Medline, Ovid Medline in Process, ChildData, CINAHL, Embase, ISI Proceedings, SIGLE, Science Citation Index, Social Science Citation Index, and TRIP databases. We included all studies that addressed rib fractures and CPR in children less than 18 years, and excluded review articles, expert opinion, consensus guidelines, and studies that were significantly methodologically flawed on critical appraisal. Each study underwent two independent reviews (with a third review if there was disagreement). Each reviewer used standardized criteria for study definition, data extraction, and critical appraisal, to determine the quality of the study and to establish if it met the inclusion criteria of this systematic review. FINDINGS: Of the 427 studies reviewed, 6 were included: 1 case control, 4 cross-sectional, and 1 case series. These represent data on 923 children who underwent CPR. Three children sustained rib fractures as a result of resuscitation; all three of these had fractures that were anterior (two mid-clavicular and one costo-chondral). We did not find any child in the literature who had a posterior rib fracture due to CPR. Resuscitation was performed variably by both medical and non-medical personnel. CONCLUSION: Rib fractures after cardiopulmonary resuscitation are rare. When they do occur, they are anterior and may be multiple. As the studies performed to date did not use the most sensitive techniques for detecting rib fractures, further prospective studies of children would be valuable to provide additional clarification on this question. 相似文献
5.
Mala Mahto Sudhesna Mohapatra G. Sumitra Smita Kaushik T. K. Mishra Alpana Saxena 《Indian journal of clinical biochemistry : IJCB》2011,26(4):420-422
Light chain disease is a variant of multiple myeloma in which the malignant population of marrow cells produces free monoclonal
light chains but no heavy chain or complete immunoglobulin. The monoclonal light chains are small enough to be freely filtered
by the kidneys and become Bence–Jones protein. Light chain disease comprises about 18% of multiple myeloma patients. Here
we present a case report of a 38-year-old man who initially presented with complaints of pain in back and low grade fever
off and on. He was found to have collapse of D9 and D12 vertebrae along with ascites and right pleural effusion and massive
proteinuria. Multiple myeloma was considered as a differential diagnosis based on the investigations but eventually the patient
was lost to follow up. This case is reported here as the light chain variant of multiple myeloma leading to deposition disease
is less commonly reported and presents considerable difficulties in diagnosis. 相似文献
6.
Halim Eshrat M. Ali Hussain Kaiser Jamil Mala Rao 《Indian journal of clinical biochemistry : IJCB》2001,16(1):77-80
The hypoglycemic effect of the aqueous extract ofAbroma augusta (Family: Steculiceae) was studied in normal as well as alloxan diabetic rats. Treatement of diabetic rats with 4 ml (4gm
dry weight) of agueous extract ofA. augusta for 16 weeks resulted in gradual but significant fall in fasting blood glucose and improvement in glucose tolerance. Serum
total and LDL cholesterol and triacylglycerol which increased in diabetic rats showed improvement. These results show that
the water extract ofA. augusta has both hypoglycemic and hypocholesterolemic effects. 相似文献
7.
This article presents a model for research on the effects of school organizational heath factors on primary school academic achievement in Trinidad and Tobago. The model can be applicable for evaluating schools in other developing countries. As proposed, the model hypothesizes relationships between external factors (exogenous variables), school-level factors (endogenous variables), and school outcomes (student achievement and positive school climate). The endogenous variables are sub-scales of school organizational health. They include principal leadership, psycho-social environment, school–home–community relationships, teacher characteristics, curriculum quality, and school culture. These subscales are partially influenced by the Organizational Health Inventory OHI (Hoy and Feldman, 1987) and by school health indices set forth by the World Health Organization (1996). It is hoped that this school organizational health model can provide a conceptual tool for formulating a more comprehensive measure of healthy schools. 相似文献
8.
Mala Mahto Mukunda Kumar Sushil Kumar Ayan Banerjee 《Indian journal of clinical biochemistry : IJCB》2021,36(2):235
Hyperkalemia is a life threatening electrolyte derangement that must be recognized and treated quickly. Pseudohyperkalemia is defined as a difference between serum and plasma potassium concentration of more than 0.4 meq/L with serum values on the higher side when both the samples are obtained at the same time, remain at room temperature and are tested within 1 h of sample collection. Given the implication of basing medical decisions on falsely elevated potassium levels, timely identification of the entity of pseudohyperkalemia and differentiating it from true hyperkalemia becomes utmost important. Here we present a case report of a 36 year old female admitted with a provisional diagnosis of pyrexia of unknown origin with hepatosplenomegaly and anaemia under evaluation. During hospital stay her potassium levels in whole blood, serum and plasma reportedly differed significantly. An abnormal WBC count beyond assay range was reported and during subsequent investigations this lead to a peripheral smear being advised and diagnosis revealed chronic lymphoblastic leukaemia with blast crisis and 86% blast cells. In patients with leukocytosis and thrombocytosis, pseudohyperkalemia may exist in the absence of electrocardiogram changes or other clinical manifestations of true hyperkalemia thus leading to reevaluation of potassium values in serum, plasma and whole blood to arrive at the true picture. 相似文献
9.
Kailash C. Garg Suresh Kumar Yennapu Madhavi Mala Bahl 《Health information and libraries journal》2009,26(1):22-31
Objectives: This study evaluates malaria vaccine research carried out in different parts of the world during 1972–2004 using different bibliometric indicators. Method: Data have been downloaded from PubMed for the period 1972–2004 using the keywords (malaria* or plasmodium or falciparum) and (vaccine*) in the title and abstract fields. The study examined the pattern of growth of the output, its geographical distribution, profile of different countries in different subfields and pattern of citations using GOOGLE Scholar. Results: Malaria vaccine research output is gradually increasing. The USA, followed by the UK and Australia contributed the highest number of papers. Publication activity has decreased in Switzerland and Sweden, but has increased in Brazil and China. The majority of the countries have focused on the development of asexual blood stage malaria. Citations per paper and incidence of high‐quality papers for the USA, the UK, Papua New Guinea and Denmark are more than the average. The majority of the prolific institutions are located in the USA, the UK, France and Australia. Conclusion: The last two decades have witnessed considerable growth in research output in this field, while a successful malaria vaccine still remains elusive. Interestingly, the countries like the USA, the UK and Australia that lead in the quantity, quality and citation of this output are often not those directly affected by malaria. 相似文献
10.
Baker AJ Brassard MR Schneiderman MS Donnelly LJ Donnelly LJ Bahl A 《Child abuse & neglect》2011,35(10):855-865