Molecularly imprinted polymers as the extracted sorbents of clenbuterol ahead of liquid chromatographic determination     

Sovichea Lay  Hai-ning Yu  Bao-xiang Hu  Sheng-rong Shen 《Journal of Zhejiang University. Science. B》2016,17(6):465-475

A pre-treatment methodology for clenbuterol hydrochloride (CLEN) isolation and enrichment in a complex matrix environment was developed through exploiting molecularly imprinted polymers (MIPs). CLEN-imprinted polymers were synthesized by the combined use of ally-β-cyclodextrin (ally-β-CD) and methacrylic acid (MAA), allyl-β-CD and acrylonitrile (AN), and allyl-β-CD and methyl methacrylate (MMA) as the binary functional monomers. MAA-linked allyl-β-CD MIPs (M-MAA) were characterized by Fourier transform-infrared (FT-IR) spectroscopy and a scanning electron microscope (SEM). Based upon the results, M-MAA polymers generally proved to be an excellent selective extraction compared to its references: AN-linked allyl-β-CD MIPs (M-AN) and MMA-linked allyl-β-CD MIPs (M-MMA). M-MAA polymers were eventually chosen to run through a molecularly imprinted solid-phase extraction (MISPE) micro-column to enrich CLEN residues spiked in pig livers. A high recovery was achieved, ranging from 91.03% to 96.76% with relative standard deviation (RSD) ≤4.45%.  相似文献   

Elementary Teachers’ Perception of Language Issues in Science Classrooms     

Lay Hoon Seah 《International Journal of Science and Mathematics Education》2016,14(6):1059-1078

Although the importance of language in science learning has been widely recognized by researchers, there is limited research on how science teachers perceive the roles that language plays in science classrooms. As part of an intervention design project that aimed to enhance teachers’ capacity to address the language demands of science, interview data (N = 9) were collected to understand teachers’ perceptions and experiences with a wide range of issues related to language use in science classrooms. Adopting an interpretive approach to qualitative data, the analysis revealed that the teachers perceive a wide range of student difficulties related to language use in science classrooms, especially to the use of specialized terms and writing. Although the teachers are keenly aware of how language can be a barrier to learning science, they are less certain as to what students need to know about the language of science in order to master it. The findings suggested professional support that highlights the distinctive language demands of science and how these demands differ from other subject areas could be useful to these elementary school teachers.  相似文献   

Using laser Doppler vibrometry to measure capillary surface waves on fluid-fluid interfaces     

James Friend  Leslie Yeo 《Biomicrofluidics》2010,4(2)

Capillary wave phenomena are challenging to study, especially for microfluidics where the wavelengths are short, the frequencies are high, and the frequency distribution is rarely confined to a narrow range, let alone a single frequency. Those that have been studying Faraday capillary waves generated by vertical oscillation have chosen to work at larger scales and at low frequencies as a solution to this problem, trading simplicity in measurement for issues with gravity, boundary conditions, and the fidelity of the subharmonic capillary wave motion. Laser Doppler vibrometry using a Mach–Zehnder interferometer is an attractive alternative: The interface’s motion can be characterized at frequencies up to 40 MHz and displacements of as little as a few tens of picometers.  相似文献   

Referee acknowledgment for 2014     

Hsueh-Chia Chang  Leslie Y. Yeo 《Biomicrofluidics》2015,9(1)

  相似文献   

Disgust,Need for Affect,and Responses to Microbiome Research     

Ye Sun  Sara K. Yeo  Meaghan McKasy  Erika Shugart 《Mass Communication and Society》2019,22(4):508-534

Contributing to the literature on affective processing and attitude formation, this study investigates the effects of a discrete emotion (disgust) and an emotional disposition (need for affect [NFA]) on support for regulation in the context of microbiome research. Data from a web-based experiment (N = 1,005) showed that experienced disgust mediated the effect of disgust-eliciting information on support for regulation. This mediated relationship was moderated by NFA. More specifically, NFA moderated the path between experienced disgust and regulatory attitudes but not that between message exposure and experienced disgust. The two dimensions of NFA played different moderating roles: Emotional approach amplified the relationship between disgust and the attitudinal outcome, whereas emotional avoidance attenuated it. The study furthers understanding about how NFA influences emotional processing and contributes to research on disgust as a relatively understudied discrete emotion.  相似文献   

Professional noticing of coordinated mathematical thinking     

Tye G. Campbell  Sheunghyun Yeo 《British Educational Research Journal》2022,48(3):488-503

Over the past three decades, research and policy in many geographic regions has promoted a shift from direct, lecture-oriented mathematics instruction to inquiry-based, dialogic forms of instruction. While theory and research support dialogic instructional approaches, some have noted that the complexities of dialogic teaching make it difficult for teachers to implement. One mechanism by which teachers can improve their decision-making practices in dialogic classrooms is learning to notice (i.e. becoming aware of learners’ processes). While research has contributed frameworks for understanding how teachers notice individual learners’ mathematical thinking, there is little conceptualization regarding how teachers notice group processes in mathematics classrooms, which is integral to dialogic instruction. We offer a noticing framework termed professional noticing of coordinated mathematical thinking that describes how teachers notice group activity in mathematics classrooms. Professional noticing of coordinated mathematical thinking is conceptualized as a bi-dimensional process: noticing groups’ mathematical activity and noticing groups’ coordinated activity. Teachers must become aware of how groups approach the mathematical and collaborative nature of a task, since both of these aspects inform whether learners develop opportunities to learn in groups. The framework describes noticing practices integral to dialogic instruction and promotes inquiry for future research related to teaching moves in dialogic classrooms.  相似文献   

Minimax optimal control of linear system with input-dependent uncertainty     

Changzhi Wu  Kok Lay Teo  Xiangyu Wang 《Journal of The Franklin Institute》2014

In this paper, the quadratic minimax optimal control of linear system with input-dependent uncertainty is studied. We show that it admits a unique solution and can be approximated by a sequence of finite-dimensional minimax optimal parameter selection problems. These finite-dimensional minimax optimal parameter selection problems are further reduced to scalar optimization problems which also admit unique solutions. Thus, the original minimax optimal control problem is solved via solving a sequence of simple scalar optimization problems. Numerical experiments are presented to illustrate the developed method.  相似文献   

The Quality of Message Ideas,Thinking and Interaction in an Asynchronous CMC Environment     

Myint Swe Khine  Lay Leng Yeap  Anthony Tan Chin Lok 《Educational Media International》2013,50(1-2):115-126

One of the major shifts in education today under the influence of information and communication technologies is that there is an increased tendency toward the use of computer-mediated communications (CMC). CMC has developed an assortment of methods from simple e-mail to wireless instant messages and synchronous and asynchronous discussions. A large portion of the research in this area focuses on the pedagogical aspects of CMC particularly on the use, strategies, effectiveness and the integration of the new technologies for teaching and learning. Some studies investigate different perspectives of interaction like keeping track of asynchronous discussion, quality of participation, interaction and collaborative or group learning. This paper reports findings from the study that examines the quality of message ideas, thinking and interaction in an asynchronous CMC environment in a teacher training institution. The authors suggest some practical strategies in the implementation of asynchronous discussions in CMC environment. La qualité des messages d’idées, de la pensée et de l’interaction dans un environnement CMC asynchrone. Un des changements majeurs dans l’éducation aujourd’hui sous l’influence de l’information et des technologies de la communication est une tendance accrue À l’usage des communications par ordinateur (Computer-mediated Communications CMC). CMC a permis le développement de tout un assortiment de méthodes depuis de simples e-mail jusqu’À des messages sans fil instantanés et des discussions synchrones et asynchrones. Une grande partie de la recherche en ce domaine est centrée sur les aspects pédagogiques des CMC en particulier sur l’emploi, les stratégies, l’efficacité et l’intégration des nouvelles technologies pour l’enseignement et l’apprentissage. Certains études examinent les perspectives différentes de l’interaction. Telles que garder la trace des discussions asynchrones, la qualité de la participation interaction et l’apprentissage en coopération ou en groupe. L’article rapporte les résultats de l’étude qui examine la qualité des messages d’idées, la pensée et l’interaction dans un environnement de CMC asynchrone dans un établissement de formation des enseignants. Les auteurs suggérent des stratégies pratiques dans l’introduction de discussions asynchrones dans un environnement CMC. Die Qualität der übermittlung von Ideen, Denken und Interaktion in einem asynchronen CMC Umfeld Eine der wichtigsten Umstellungen der heutigen Ausbildung ist die unter dem Einfluss von Informations- und Kommunikationstechnologien verstärkte Tendenz, rechnergestützte Kommunikation (computer-mediated communications:CMC)

zu benutzen. CMC hat ein ganzes Arsenal von Methoden entwickelt, von der einfachen E-Mail bis zu drahtlosen Nachrichten und synchron oder asynchron geführten Diskussionen. Die Forschung in diesem Bereich konzentriert sich hauptsächlich auf die pädagogischen Aspekte von CMC, besonders auf die Nutzung, die Strategien, den Wirkungsgrad und die Möglichkeiten der Einbindung der Neuen Technologien zum Lehren und Lernen. Einige Arbeiten erforschen die verschiedenen Perspektiven

der Interaktion wie das Verfolgen von asynchronen Diskussionen, die Qualität der Beteiligung, der Interaktion und Zusammenarbeit oder dem Lernen in Gruppen. In diesem Beitrag wird über Ergebnisse der Studie zur Untersuchung der Qualität der übermittlung von Ideen, Gedanken und Interaktionen in einem asynchron arbeitenden rechnergestützten

System (CMC) einer Lehrerfortbildungseinrichtung berichtet. Die Autoren erläutern praktische Strategien zur Einbindung asynchroner Diskussionen in eine CMC-Umgebung.  相似文献   

Impact of gender and prior knowledge on learning performance and motivation in a digital game-based learning biology course     

Yeo  Jun-Hui  Cho  I.-Hsuan  Hwang  Gwo-Haur  Yang  Hsi-Hsun 《Educational technology research and development : ETR & D》2022,70(3):989-1008

Educational technology research and development - Gender and prior knowledge may affect students' performance and motivation when simulations and games are used for learning. Accommodations...  相似文献   

The Home Literacy Environment and Preschool Children's Reading Skills and Interest     

Lay See Yeo  Winston W. Ong  Charis M. Ng 《Early education and development》2014,25(6):791-814

Research Findings: This study explored the association between the home literacy environment (HLE), conceptualized as comprising parents’ reading beliefs and home literacy practices, and preschoolers’ reading skills and reading interest. It also identified factors in the HLE that predict emerging reading competence and motivation to read. A total of 193 children age 6 years from 14 preschools across Singapore and their parents participated in the study. The parents completed a reading belief inventory, a family literacy activity inventory, and a demographic questionnaire that surveyed the child's reading interest. The children were administered a battery of standardized literacy tests. The study found a moderate relationship between the HLE and children's reading competencies and a strong relationship between the HLE and children's reading interest. When parents’ education level and children's age were controlled, hierarchical multiple regression analyses found that family literacy activities contributed more unique variance to children's reading outcomes and reading interest than did parents’ reading beliefs. Active parental involvement was the strongest component of the HLE, with parent–child engagement in reading and writing emerging as the best predictor of both the child's emerging reading skills and reading interest. With respect to reading beliefs, parents’ efficacy in supporting literacy development before their child attended school positively predicted reading competence, as did parents’ affect and verbal participation in fostering reading interest. However, verbal participation negatively predicted Singapore children's reading competence. Practice or Policy: The implications of the results were discussed.  相似文献