Carnosine in health and disease     

Guilherme Giannini Artioli  Craig Sale  Rebecca Louise Jones 《European Journal of Sport Science》2019,19(1):30-39

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   

A school’s journey in creating a relational environment which supports attachment and emotional security     

Louise Webber 《Emotional and Behavioural Difficulties》2017,22(4):317-331

This article focuses on teachers’ experiences of supporting looked after and adopted children in one case study primary school in England. Children who are looked after and adopted may have a disrupted attachment with their primary carer which has resulted in an insecure attachment. Children with insecure attachments can feel anxious, uncertain and have low self-worth which can result in a struggle to adapt to school as they are unable to articulate their feelings. This article draws on qualitative research using semi-structured interviews with teaching staff in order to illuminate strategies, subsidised through Pupil Premium Plus funding, to support such children. A key outcome was the creation of a school-based model consisting of six main components that can be developed to support children with insecure attachments.  相似文献   

Curriculum,pedagogies and assessment in Scotland: the quest for social justice. ‘Ah kent yir faither’   总被引：1，自引：0，他引：1  

E. Louise Hayward 《Assessment in Education: Principles, Policy & Practice》2007,14(2):251-268

This paper explores the ways in which assessment has developed and is developing in Scotland. The article begins by providing background information on Scotland's educational system. The second section tracks the relationship between curriculum and assessment in Scotland for children aged 3–14, 14–16 and 16+. The third section explores Scotland's current attempt to develop a coherent assessment system. The fourth section focuses on the major curriculum review presently underway in Scotland and reflects on the emerging future for Scottish Education. Connections between ideas of Learning, Assessment and Excellence are explored and issues being faced by one small country trying to develop a coherent assessment system that is both just and dependable are identified.  相似文献   

Identifying dyslexia in multilingual students: can phonological awareness be assessed in the majority language?     

Louise Miller Guron  Ingvar Lundberg 《Journal of Research in Reading》2003,26(1):69-82

A study of 97 students from two schools in Göteborg, Sweden, examined reading proficiency and phonological skill using a comprehensive battery of group measures in the classroom. The sample comprised 38 monolingual native‐Swedish speakers, and 59 multilingual students for whom Swedish is an additional language. Students were administered tests of non‐verbal intelligence, vocabulary, reading comprehension, word recognition and non‐vocal phonological tasks. Two sub‐groups of 26 monolingual and 26 multilingual students, matched on non‐verbal intelligence, also participated in oral word and nonword reading tasks. No significant differences were found between language groups on the separate phonological subtests or the composite phonological score after controlling for non‐verbal intelligence in hierarchical regression analyses. The language groups were equally represented at the 20th percentile on both composite phonology and word reading measures. The composite phonological score was equally powerful for both language groups in predicting word recognition. The results of the present study suggest that, given sufficient exposure to the majority language, it is possible to assess a range of phonological skills among speakers of minority languages using the same battery of tasks as for native speakers.  相似文献   

Class,gender, (hetero)sexuality and schooling: paradoxes within working‐class girls’ engagement with education and post‐16 aspirations     

Louise Archer  Anna Halsall  Sumi Hollingworth 《British Journal of Sociology of Education》2007,28(2):165-180

This paper discusses the ways in which inner‐city, ethnically diverse, working‐class girls’ constructions of hetero‐femininities mediate and shape their dis/engagement with education and schooling. Drawing on data from a study conducted with 89 urban, working‐class young people in London, attention is drawn to three main ways through which young women used heterosexual femininities to construct capital and generate identity value and worth; namely, investment in appearance through ‘glamorous’ hetero‐femininities, heterosexual relationships with boyfriends, and the ‘ladettte’ discourse. We discuss how and why young women’s investments in particular forms of heterosexual working‐class femininity can play into their disengagement from education and schooling, drawing particular attention to the paradoxes that arise when these constructions play into other oppressive power relations.  相似文献   

Role of exteroceptive background context in taste-aversion conditioning and extinction     

Trevor Archer  Per-Olow Sjödén  Lars-Göran Nilsson  Ned Carter 《Learning & behavior》1979,7(1):17-22

In two experiments, saccharin (CS) and lithium chloride (US) were paired in a context consisting of specific visual, auditory, tactual, and olfactory cues. The saccharin aversion was then extinguished in a context free from conditioning-context cues. Later, saccharin preference tests were given in the presence and absence of these cues. The results indicated that the background cues of the conditioning trial controlled the amount of saccharin drunk on extinction trials, and, furthermore, that extinction of the taste aversion was context specific; i.e., groups given extinction trials in a different (from conditioning) context retained their saccharin aversion in the conditioning context only. The results indicate an important role played by the exteroceptive context in taste-aversion conditioning.  相似文献   

The Web and information literacy: scaffolding the use of web sources in a project-based curriculum     

Marion Walton  Arlene Archer 《British journal of educational technology : journal of the Council for Educational Technology》2004,35(2):173-186

In this article we describe and discuss a three‐year case study of a course in web literacy, part of the academic literacy curriculum for first‐year engineering students at the University of Cape Town (UCT). Because they are seen as ‘practical’ knowledge, not theoretical, information skills tend to be devalued at university and rendered invisible to the students. In particular, web‐searching skills are problematic, given the challenges that the Web poses to academic values and traditional research practices. Consequently, the technical skills of web searching are often taught separately from academic curricula or left entirely unaddressed. We illustrate an alternative, integrated approach to the development of this aspect of information literacy. We apply a critical action research methodology to document, evaluate and reflect on students’ use of evaluative frameworks. Focusing on the facilitation of critical and evaluative use of the Web for exploratory learning, we interrogate the role of ‘cultural capital’ and evaluate the effectiveness of the scaffolding provided by the course design. We find important connections between developing knowledge of academic discourse and successful academic use of the Web, and note that, for students to transfer their skills to a range of contexts, these skills will require sustained attention throughout the undergraduate curriculum. We present evidence that the most effective strategies integrate everyday practical knowledge of research techniques with teaching about academic discourse and building students’ knowledge in a specific domain.  相似文献   

‘They never go off the rails like other ethnic groups’: teachers’ constructions of British Chinese pupils’ gender identities and approaches to learning     

Louise Archer  Becky Francis 《British Journal of Sociology of Education》2005,26(2):165-182

This paper examines the ways in which British Chinese pupils are positioned and represented within the popular/dominant discourse of teachers working in London schools. Drawing on individual interviews from a study conducted with 30 teachers, 80 British Chinese pupils and 30Chinese parents, we explore some of the racialised, gendered and classed assumptions upon which dominant discourses around British Chinese boys and girls are based. Consideration is given, for example, to teachers’ dichotomous constructions of British Chinese masculinity, in which British Chinese boys were regarded as ‘naturally’ ‘good’ and ‘not laddish’, compared with a minority of ‘bad’ British Chinese boys, whose laddishness was attributed to membership of a multiethnic peer group. We also explore teachers’ constructions of British Chinese femininity, which centred around remarkably homogenised representations of British Chinese girls as ‘passive’ and quiet, ‘repressed’, hard‐working pupils. The paper discusses a range of alternative readings that challenge popular monolithic and homogenising accounts of British Chinese masculinity and femininity in order to open up more critical ways of representing and engaging with British Chinese educational ‘achievement’.  相似文献   

Work values in relation to gender and forecasted career patterns for women     

Jacques Perron  Louise St-Onge 《International journal for the advancement of counseling》1991,14(2):79-90

This study examined the problem of life-style and career patterns for women. College students (367 males, 332 females) expressed their preferences for one of three career patterns for women combining work and family involvement and also answered a work values questionnaire. Results showed that 70.5% of the subjects expected women to attend school and/or work outside the home first and to have their child(ren) only after they have established themselves in a career. Forecasting of career patterns for women was significantly related to subjects' work values. Results confirmed previous findings and also indicated new trends in work values that differentiate between male and female college students.Université de MontréalUniversité du Québec à Trois-Rivières  相似文献   

浅析心理学在中国文明进程中的作用     

路易斯·希金斯 《顺德职业技术学院学报》2004,2(1):74-76

分析中国心理学的历史、发展和现状,指出中国文明和心理学在人类历史上辉煌的过去,描述现代心理学在中国的发展和现存的不足,将中西方的心理学进行对比分析。  相似文献