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Alumina nanoparticles (A1NP) were synthe- sized from aluminium nitrate using extracts of tea, coffee and triphala--a well known herbal plant as well as a non- toxic and eco--friendly green material. The synthesis was carried out taking 1:4 ratio of metal salt and these extracts under microwave irradiations at 540 W, which gave better yield of nanoparticles. Water was taken as solvent medium. The formations of A1NP were initially monitored by the colour changes occurring in the reaction mixture during the incubation period. As synthesized nanoparticles were characterized by scanning electron microscope (SEM), UV-Visible (UV-Vis) spectroscopy and Fourier transform infrared spectroscopy (FTIR). The A1NP were found to be spherical in shape in case of tea and coffee extracts with a size of 50-200 nm and to be oval shaped in case of triphala extract with an average size of 200-400 nm. The formation of A1NP with the microwave-assistance using these plant extracts has proved to be very faster than any other methods. In addition, excellent reproducibility of these nanoparticles, without the use of any additional capping agent or stabilizer will have great advantages in compari- son with microbial synthesis, avoiding all the tedious and hygienic complications.  相似文献   
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Aminotransferase assay is often used as a screening test as well as an endpoint for resolution of disease in nonalcoholic fatty liver disease (NAFLD). Aim of the study was to evaluate the relationship of transaminase level with metabolic variables and histology in NAFLD. Single center observational study was conducted in a gastroenterology clinic at Cuttack in coastal Odisha. Subjects were consecutive patients presenting with functional bowel disease and undergoing abdominal sonography. All participants were evaluated for the presence of metabolic syndrome (MS), insulin resistance, liver function test and lipid profile. Various parameters were compared between NAFLD subjects and controls. 53.5 % of NAFLD had normal serum transaminases, whereas 20.8 % of healthy controls had transaminitis. NAFLD patients had significantly higher BMI, fasting plasma glucose, serum transaminases, serum triglycerides, serum insulin and homeostatic model assessment (HOMA) IR than controls. NAFLD patients who had transaminitis had significantly higher incidence of MS and higher mean HOMA IR than those without. There was no significant difference in histopathological features between NAFLD with and without transaminitis. To conclude, over half of NAFLD subjects do not have transaminitis while transaminitis is present in a fifth of healthy people without fatty liver. Hence serum transaminase should not be used as screening test for NAFLD. NAFLD patients with transaminitis had a higher incidence of MS and insulin resistance than those without. However, there was no significant difference in histopathological features between these two groups.  相似文献   
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