Biomarkers of inflammation and cardiac remodeling: the quest of relevant companions for the risk stratification of heart failure patients is still ongoing     

Gruson D  Ahn SA  Rousseau MF 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2011,21(3):254-263

Heart failure (HF) is a frequent chronic disease in elderly people and represents a major health and economic burden. The accurate diagnosis of HF and the identification of high risk patients is mandatory to select the appropriate therapy and care. HF is associated to cardiac remodeling and inflammation and to the release of neurohormones. If natriuretic peptides remain the biomarkers of choice for the diagnosis and the prognosis of HF, several biomarkers related to cardiac remodeling and inflammation are available for testing and may add valuable information for the risk estimation of HF patients and for the selection of the most appropriated therapy. Furthermore, the quest for new efficient biomarkers of cardiac remodeling and inflammation is still ongoing and new candidates have been identified for a potential use in daily clinical practices. However, before their potential translation to routine parameters several challenges ranging form the analytical validation to the cost-effectiveness estimation should be considered.  相似文献   

论康德的道德自由与德性论   总被引：1，自引：0，他引：1  

萨·巴特尔 《内蒙古师范大学学报(哲学社会科学版)》2008,37(1):37-41

理性与自由是康德伦理学的重要概念,如若把康德的“理性”概念分为理论理性和实践理性,那么他的“自由”概念同样也可分为理性的自由和道德的自由。理论理性和理性的自由是属于思辨哲学研究的范畴,实践理性和道德的自由是属于伦理学研究的范畴。在康德看来,道德自由是人的道德活动之原因,德性是人的道德活动之结果。因此,在康德伦理学中道德自由与德性之间有着内在的逻辑联系,不仅如此,这种道德自由与德性之内在的逻辑联系恰恰体现着康德理性主义伦理思想的精神内涵。  相似文献   

Facial expressions when learning with a Queer History App: Application of the Control Value Theory of Achievement Emotions     

Byunghoon “Tony” Ahn  Jason M. Harley 《British journal of educational technology : journal of the Council for Educational Technology》2020,51(5):1563-1576

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On-demand electrostatic droplet charging and sorting     

Ahn B  Lee K  Panchapakesan R  Oh KW 《Biomicrofluidics》2011,5(2):24113

This study reports a droplet-based microfluidic device for on-demand electrostatic droplet charging and sorting. This device combines two independent modules: one is a hydrodynamic flow focusing structure to generate water-in-oil droplets, and the other is the two paired-electrodes for charging and sorting of the droplets. Depending on the polarity on charging electrodes, water-in-oil droplets can be electrostatically charged positively or negatively, followed by automatic real-time electric sorting. This approach will be useful when preformed droplets, with a positive, a negative, or with no charge, need to be manipulated for further on-chip droplet manipulation.  相似文献   

On orthogonal polynomials     

E.I. Jury  S.M. Ahn 《Journal of The Franklin Institute》1975,300(3):169-173

A study is made of the orthogonal polynomials on certain curves in the complex plane. Necessary and sufficient conditions for a set of polynomials to be orthogonal on the curves are obtained in terms of symmetric matrices. The relations of the symmetric matrices to Toeplitz matrices and innerwise matrices are shown.  相似文献   

Rewarding knowledge sharing under measurement inaccuracy     

Dong-Joo?LeeEmail author  Jae-Hyeon?Ahn 《知识管理研究与实践》2005,3(4):229-243

Knowledge sharing is a critical step for successful knowledge management. However, sharing knowledge not only requires time and effort of a knowledge worker but also reduces the unique value or power that the worker enjoys in the organization. Therefore, for successful knowledge sharing, a reward system is used to compensate knowledge sharing activities. In this paper, we consider a situation where there exists measurement inaccuracy in the actual amount of knowledge shared by risk-averse workers. We analyze the optimal reward system for knowledge sharing and the optimal investment to address measurement inaccuracy. Through the analysis, a simple optimal reward system is derived. This system is linear in the amount of knowledge sharing and compensates for the workers’ costs of knowledge sharing and risk-bearing. Additionally, the optimal investment to improve measurement accuracy is characterized by balancing the investment cost against the workers’ risk-bearing cost. Finally, a comparative statics analysis is conducted to investigate the effect of changes in exogenous factors on the optimal reward system, the amount of knowledge sharing, and the amount of optimal investment. Insights from our analysis can contribute to the better management of knowledge sharing through reward systems and the effective implementation of a knowledge management system.  相似文献   

What Develops in Infants’ Spatial Categorization? Korean Infants’ Categorization of Containment and Tight‐Fit Relations          下载免费PDF全文

Marianella Casasola  Yeojin A. Ahn 《Child development》2018,89(4):e382-e396

Korean‐learning infants’ categorization of two spatial categories, one consistent and one inconsistent with the Korean semantic category of “kkita,” was examined. Infants of 10 months (n = 32) and 18 months (n = 49) were tested on their categorization of containment or tight fit spatial relations. At 10 months, infants only formed a category of containment, but at 18 months, their categorization of tight fit was significantly stronger than containment. The results suggest that Korean infants benefit from their language environment in forming a category of tight fit when the exemplars are perceptually diverse. In particular, infants’ language environment may bolster their ability to generalize across diverse exemplars to form abstract categorical representations of spatial relations.  相似文献   

Service-Learning: Implications for the Academic,Personal, and Professional Development of Criminal Justice Majors     

Helen Ahn Lim 《Journal of Criminal Justice Education》2018,29(2):237-248

An exploratory senior and alumni survey was administered to better assess the experiential learning opportunities, including Service-Learning, offered to students in a criminal justice department. This article highlights the academic, personal and professional development of students, based on the perception of criminal justice majors in the department who completed a Service-Learning course. Educators continue to assess the academic outcomes for students and the benefits to the community. What may be less appreciated is how Service-Learning can also benefit students in their professional skills development. This article illustrates these potential benefits, and also discusses why Service-Learning courses are a critical part of development for criminal justice majors.  相似文献   

Actions and Conceptions: Exploring Initial Literacy Teaching Practice for Adults     

Helena Colliander  Song Ee Ahn  Per Andersson 《Journal of Language, Identity & Education》2018,17(5):306-319

Given that it is a delicate task to meet the educational needs of adult emergent readers in a second language setting, this study serves to explore the teaching practice of teachers working with learners of initial literacy and second language. Based on a situated learning perspective, data from 16 lesson observations of nine teachers is analysed. The findings show that teachers initiate and negotiate learning activities, strive to get the students to understand words and other symbols, facilitate participation within and outside the classroom and negotiate the acceptable student behaviour. These findings suggest that Literacy Education and Second Language Learning for Adults (LESLLA) teaching and learning is a particular practice, where the teachers’ actions are intertwined with those of the learners and with the teachers’ conceptions of the learners. In that way, the teachers’ actions do not only speak of the learners, but also of their own professional identity.  相似文献   

Optimal residual generation for fault detection in linear discrete time-varying systems with uncertain observations     

Yueyang Li  Hamid Reza Karimi  Choon Ki Ahn  Yuan Xu  Dong Zhao 《Journal of The Franklin Institute》2018,355(7):3330-3353

This work deals with the problem of optimal residual generation for fault detection (FD) in linear discrete time-varying (LDTV) systems subject to uncertain observations. By introducing a generalized fault detection filter (FDF) with four parameter matrices as the residual generator, a novel FDF design scheme is formulated as two bi-objective optimization problems such that the sensitivity of residual to fault is enhanced and the robustness of residual to unknown input is simultaneously strengthened. A generalized operator based optimization approach is proposed to deduce solutions to the corresponding optimization problems in operator forms, where the related H_∞/H_∞ or $H_{?}/H_{\infty }$ FD performance index is maximized. With the aid of the addressed methods, the connections among the derived solutions are explicitly announced. The parameter matrices of the FDF are analytically derived via solving simple matrix equations recursively. It is revealed that our proposed results establish an operator-based framework of optimal residual generation for some kinds of linear discrete-time systems. Illustrative examples are given to show the applicability and effectiveness of the proposed methods.  相似文献