排序方式： 共有17条查询结果，搜索用时 250 毫秒
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Mohammad Abdi Mohammad Said Hakhamaneshi Mohammad Reza Alaei Namam-Ali Azadi Rahim Vakili Daniel Zamanfar Mohammad Taghikhani Shohreh Khatami 《Indian journal of clinical biochemistry : IJCB》2015,30(3):318-322
Methods for assaying lysosomal diseases in dried blood samples are very useful today due to its several advantages related to the stability of samples, its transportation, handled and analysis, and its potential use for newborn screening compared to traditional methods in leucocytes samples. For this reason, it is important to validate these assays before being used in routine laboratory. Because of different in biological markers based on ethnicity, we aimed this study to validation a DBS-based fluorometric assay for measurement of α-l-Iduronidase activity for diagnosis of MPS I patients in Iran. DBS samples were collected from 15 MPS I patients and 60 healthy age matched subjects. Diagnostic value, biological variance and α-l-Iduronidase activity were determined. DBS α-l-Iduronidase activity was significantly higher in male subjects than in female group. Using a cut-off level of 1.08 µmol/spot 20 h, sensitivity and specificity were 100 and 98 %. The linearity of test was proved and we showed that within-run and between run precision were 5.6 and 14.66 %. Measurement of α-l-Iduronidase activity in DBS samples is an accurate test for diagnosis of MPS I and because of its rapid shipping and simplicity to keeping, DBS-based enzyme activity could be considered as a useful diagnostic tool in this disease. 相似文献
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This qualitative study explores the narratives of 12, first-generation, queer, Iranian-American women in an attempt to better understand the experiences of being both Iranian and queer, and to explore the various ways participants manage their sexual identities within their ethnic communities. Online interviews were analyzed using grounded theory analysis, which revealed that shame anxiety motivates the fostering of network ignorance. Feelings of fear and guilt, which together cultivate shame anxiety, motivate the identity management strategies of queer Iranian women as they attempt to foster ignorance of their sexual orientation within the Iranian community. Strategies include (co)-covering, deceiving and passing, and avoiding. 相似文献
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An experiment was carried out concerning arithmetical problem solving in children. Three between sujects variables were manipulated. All problems followed the same underlying pattern with an initial state (Ei), two additive transformations (T1 and T2), and a final state (Ef); yet the unknown state concerned either Ef (S1 problems) or Ei (S2 problems). The order of introducing the transformations was counterbalanced: either state first (O1 order) or transformations first (O2). Finally, the question was located either at the end of the problem (Q1) or at its beginning (Q2). One hundred and ninety two subjects (64 six, eight, and ten year-olds) were submitted to 8 different problems of the same type. The difficulties of the numerical series were tentatively controlled on an atempt to render the computations roughly «proportional» to ages. Quantitative and qualitative analysis were conducted. Results show that: a) Problems with final state unknown (S1) are solved more easily and early, whereas problems with initial state unknown (S2) are better solved as the children grow older. b) Introducing the transformations first (O2) and placing the question at the beginning of the problem-text (Q2) yields better performances c) The procedures used to solve the problems are clearly dependant on the wording of the problems. An interpretation is proposed which takes in account both the knowledge available in L.T.M. and the limitations of working memory. 相似文献
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Yumiko Otsuka Yukuo Konishi So Kanazawa Masami K. Yamaguchi Hervé Abdi Alice J. O'Toole 《Child development》2009,80(4):1259-1271
This study compared 3- to 4-month-olds' recognition of previously unfamiliar faces learned in a moving or a static condition. Infants in the moving condition showed successful recognition with only 30 s familiarization, even when different images of a face were used in the familiarization and test phase (Experiment 1). In contrast, infants in the static condition showed successful recognition only when the familiarization duration was lengthened to 90 s and when the same image was used between the familiarization and test phase (Experiments 2 and 3). Furthermore, presentation of multiple static images of a face did not yield the same level of performance as the moving condition (Experiment 4). These results suggest that facial motion promotes young infants' recognition of unfamiliar faces. 相似文献
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The analysis of circular concrete columns using unconfined concrete models is a well established practice. However, there is a necessity to develop realistic analysis and design tools that predict the extreme ultimate capacity of such columns since modern codes and standards like AASHTO LRFD are introducing extreme load events. The increase in strength and ductility due to full axial confinement is not applicable to pure bending and bending plus axial load simply because the area of effective confined concrete is reduced. The higher the eccentricity the smaller the compressed portion of the confined core. Accordingly, the ultimate confined strength is gradually reduced from the fully confined value fcc′ (at zero eccentricity) to the unconfined value fc′ (at infinite eccentricity) as a function of eccentricity to diameter ratio. A numerical analysis algorithm is developed using the finite layer procedure and the secant stiffness approach within a framework of incremental-iterative moment of area computations. The resulting nonlinear section analysis requires radial loading in which the eccentricity is kept constant or the axial load is proportional to the applied moment. The results are compared with existing experimental data and the widely used Mander model to benchmark the present predictions. 相似文献
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Güngör Abdi Sari Halil I. 《International journal for the advancement of counseling》2022,44(3):414-431
School burnout refers to psychological reactions to academic stress and loads and has been identified as a risk factor contributing to academic failure and subsequent mental health challenges. However, academic motivation, hope, and meaning in life can be potential combating factors against school burnout. This study aimed to examine the effects of academic motivation on school burnout in college students and explore mediator roles of hope and meaning in life. A path analysis was performed with the data collected from 544 Turkish college students to test the direct and indirect effects. The results showed that the direct effects from the three academic motivation variables to school burnout variables were larger than the indirect effects. Both mediators played roles in the relations between amotivation and efficacy and intrinsic motivation and efficacy. The last finding was that hope played more significant mediator roles than meaning in life. The results were discussed, along with implications for faculty, college counselors, and future studies.
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Asad Abdi Siti Mariyam Shamsuddin Ramiz M. Aliguliyev 《Information processing & management》2018,54(2):318-338
Sentiment analysis concerns the study of opinions expressed in a text. This paper presents the QMOS method, which employs a combination of sentiment analysis and summarization approaches. It is a lexicon-based method to query-based multi-documents summarization of opinion expressed in reviews.QMOS combines multiple sentiment dictionaries to improve word coverage limit of the individual lexicon. A major problem for a dictionary-based approach is the semantic gap between the prior polarity of a word presented by a lexicon and the word polarity in a specific context. This is due to the fact that, the polarity of a word depends on the context in which it is being used. Furthermore, the type of a sentence can also affect the performance of a sentiment analysis approach. Therefore, to tackle the aforementioned challenges, QMOS integrates multiple strategies to adjust word prior sentiment orientation while also considers the type of sentence. QMOS also employs the Semantic Sentiment Approach to determine the sentiment score of a word if it is not included in a sentiment lexicon.On the other hand, the most of the existing methods fail to distinguish the meaning of a review sentence and user's query when both of them share the similar bag-of-words; hence there is often a conflict between the extracted opinionated sentences and users’ needs. However, the summarization phase of QMOS is able to avoid extracting a review sentence whose similarity with the user's query is high but whose meaning is different. The method also employs the greedy algorithm and query expansion approach to reduce redundancy and bridge the lexical gaps for similar contexts that are expressed using different wording, respectively. Our experiment shows that the QMOS method can significantly improve the performance and make QMOS comparable to other existing methods. 相似文献
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Ali A Abdi 《Compare》2001,31(2):229-244
With the integration of the education system in liberated South Africa, social development expectations should be justifiably high, especially for the country's long-oppressed black majority. The concretisation of these expectations is being, or will be, determined by a myriad of converging and diverging possibilities and difficulties. This article focuses on the problems of education and development in post-apartheid South Africa, with a sustained emphasis on the importance of looking beyond the current political triumph. The new areas of constant and consistent focus must become, the author proposes, the disturbingly uneven terrains of educational attainment and long-term socio-economic development. By stressing the urgency of these cases, the article highlights actual possibilities as well as the magnitude of hindering factors in educational development that are still affecting millions of lives in the new South Africa. The article ends with a call for the pragmatic reconstitution of South Africa's development education actualities to make this country a prosperous space for all South Africans now and into the future. 相似文献