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K. Poornima M. Cariappa K. Asha H. P. Kedilaya M. Nandini 《Indian journal of clinical biochemistry : IJCB》2003,18(2):197-205
An adequate antioxidant reserve which is usually present in a vegetarian diet is associated with higher life expectancy. On
the other hand habitual consumption of fish is associated with lower risk of cardiovascular diseases which is attributed to
the polyunsaturated fatty acids (PUFA) present in it. However the PUFA are readily susceptible to oxidation leading to the
formation of free radicals which is known to be involved in the causation of several diseases.
The oxidant-antioxidant status of 23 vegetarians and 22 fish eaters was studied by determining the plasma lipid peroxides
measured as malondialdehyde (MDA) and the antioxidants, viz. glutathione (GSH), ascorbic acid, ceruloplasmin and uric acid.
Results show that the ascorbic acid values were significantly higher in vegetarians. In addition, MDA correlated negatively
with ascorbic acid only in vegetarians. However, correlation of MDA with glutathione showed a significant negative correlation
only in fish eaters. There was no statistically significant difference in the MDA, GSH, ceruloplasmin and uric acid levels.
The mechanism behind these findings are not clear and needs to be explored. 相似文献
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Sian E. Slawson Paul P. Conway Jodi Cossor Nandini Chakravorti Andrew A. West 《Journal of sports sciences》2013,31(5):468-478
Abstract Work presented in this paper provides a methodology for categorising swimming start performance based on peak force production on the main block and footrest components of the Omega OSB11 starting block. A total of 46 elite British swimmers were tested, producing over 1000 start trials. Overwater cameras were synchronised to a specifically designed start block that allowed the measurement of force production via two sets of four, tri-axis, force transducers; one set in the main block and one in the footrest. Data were then analysed, segregating trials for gender. Each start was categorised, with respect to the peak force production in horizontal and vertical components, into one of nine categories. Three performance indicators, i.e. block time, take-off velocity and distance of entry, were used to assess whether differences in performance could be correlated with these categories. Results from these data suggest that swimmers generating higher than average peak forces were more likely to produce a better overall start performance than those who produced forces lower than the average, for this population of athletes. 相似文献
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M. Cariappa K. Poornima M. Nandini K. Asha H. P. Kedilaya 《Indian journal of clinical biochemistry : IJCB》2005,20(1):103-108
Habitual consumption of moderate amounts of fish is associated with reduced mortality from coronary heart disease. However
the beneficial effects of fish enriched diet seem contradictory, due to the susceptibility of the PUFAs in them to oxidation.
It is also acclaimed that vegetarians in general, have a lower serum total cholesterol and LDL-cholesterol and a better antioxidant
status. This contradiction was the basis for the study, where the validity of the above finding was tested in a general population
consuming a vegetarian or predominantly fish diet as a regular dietary habit. The oxidant status and the lipid profile of
23 vegetarians and 22 fish eaters was studied by estimating the plasma lipid peroxides measured as malondialdehyde (MDA) and
the lipid parameters viz. Total Cholesterol (TC), HDL-Cholesterol (HDL-C) and triglycerides (TG). Statistical analysis was
carried out to compare the MDA values and the lipemic status between the two groups. MDA was also correlated with the various
lipid indices among the study groups. None of the compared and correlated values was statistically significant, although certain
altered trends were seen. From this study, it may be concluded that oxidant status and lipid profile does not vary significantly
in the two groups, suggesting that neither a vegetarian diet nor a fish diet has a definite benefit over the other. 相似文献
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Ronald C. Plotnikoff Sonia Lippke Melissa Reinbold-Matthews Kerry S. Courneya Nandini Karunamuni Ronald J. Sigal 《Measurement in physical education and exercise science》2013,17(2):73-91
This study was designed to test the validity of a transtheoretical model's physical activity (PA) stage measure with intention and different intensities of behavior in a large population-based sample of adults living with diabetes (Type 1 diabetes, n?=?697; Type 2 diabetes, n?=?1,614) and examine different age groups. The overall specificity (classified correctly as inactive) for Type 1 diabetes was 69.3% based on the percentage of individuals in precontemplation, contemplation, and preparation not meeting Canada's PA guidelines. Sensitivity (classified correctly as active) was 82.5% based on the proportion of active participants in action and maintenance. In the Type 2 diabetes group, the overall specificity and sensitivity was 63.9% and 88.2%, respectively. No significant differences were found between the diabetes groups for stage distribution patterns, and sensitivity and specificity values. The majority of the study hypotheses related to intention and behaviors were confirmed, providing further supportive evidence for the utility of this PA staging measure for the diabetes population. 相似文献
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Charu Yadav Afzal Ahmad Benedicta D’Souza Ashish Agarwal M Nandini K Ashok Prabhu Vivian D’Souza 《Indian journal of clinical biochemistry : IJCB》2016,31(2):240-242
Non-Hodgkin’s lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50–75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin’s lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus). 相似文献
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M. Nandini M. Abdul Rahiman S. Narasimha Rao 《Indian journal of clinical biochemistry : IJCB》2000,15(2):161-166
The effect of dietary supplementation with Oil sardine (Sardinella longiceps) fish at 2/3 fat replacement, on serum lipids in the cholesterol-stressed copper loaded rats was studied. Hypercholesterolemic
state observed during copper toxicity was not alleviated by sardines. Copper loading significantly decreased the triglyceride
levels and the activity of β-hydroxy β-methyl glutaryl (HMG) CoA reductase. Fish supplementation was further effective in
reducing the triglyceride levels in copper loaded rats. Significant increase in the serum phospholipid was observed in the
fish supplemented rats during copper overload. The finding suggests that hypolipidemic potential of fish is certainly altered
to some extent in copper toxicity since, it is well known that copper enhances the formation of free radicals. Thus it may
be concluded that sardine fish is not effective in reducing the cholesterol levels during copper toxicity. 相似文献
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Permeating across societies and cultures, music is a companion to millions across the globe. Despite being an abstract art form, music affects all of us deeply, encouraging us in periods of difficulty, comforting us in moments of sadness and celebrating with us in times of joy. In recent years, neuroscientists have recognized that listening to and producing music involves a tantalizing mix of practically every human cognitive function. Thus, music has emerged as an invaluable tool to study varying aspects of the human brain such as auditory and motor perception and learning, attention, memory, and emotion. In this paper, we will discuss the different attributes of music and the neural structures associated with them. We will also highlight some recent work in our laboratory at the National Brain Research Centre in India on emotions associated with Hindustani rāga music. 相似文献
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Afzal Ahmad Benedicta D’Souza Charu Yadav Ashish Agarwal Anand Kumar M. Nandini Vivian D’Souza A. M. Poornima Nutan Kamath 《Indian journal of clinical biochemistry : IJCB》2016,31(4):480-482
Alstrom’s syndrome (AS) is a rare autosomal recessive ciliopathic condition affecting 1:10,00,000 children. It’s a single gene disorder of ALMS1 on chromosome 2 with multisystem involvement with cone-rod retinal dystrophy causing juvenile blindness, obesity, insulin resistance, type 2 Diabetes mellitus, hypogonadism and sensorineural hearing loss. Till now only 800 patients with this disorder has been identified so far. In this report, we describe the case of a 9-year old male boy from south India. He had been initially referred for polyphagia, polyuria, polydipsia, generalized weakness from 1 weeks. On examination he was demonstrated features suggestive of AS, including blindness, obesity, type 2 diabetes, altered lipid profile, hypogonadism, acanthosis nigricans, seborrheic dermatitis, right ear discharge and episodes of respiratory tract infections. So, diagnosis of AS is critical as it can easily be overlooked because of the many features associated with metabolic syndrome starting at age 7, a relatively early age. 相似文献