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Serum alkaline phosphatase (ALP) (EC 3.1.3.1), 5′nucleotidase (5′NT) (EC 3.1.3.5), aldolase (ALD) (EC 4.1.2.13) and sorbitol
dehydrogenase (SDH) (EC 1.1.1.14) were estimated in infective hepatitis, alcoholic hepatitis, chronic active hepatitis, obstructive
jaundice, cirrhosis of liver and amoebic liver abscess. It was observed that serum ALP and 5′NT were significantly increased
in all cases of chronic active hepatitis and obstructive hepatic disease. However, the elevation observed in the latter was
much higher than the former. Serum SDH and ALD levels were elevated in all cases of infective hepatitis, studied though increase
in the former was much higher than the latter, suggesting its significance in the diagnostic confirmation of this disease.
Results presented suggest 5′NT and SDH as more reliable diagnostic test compared to ALP and ALD for obstructive jaundice and
infective hepatitis respectively. 相似文献
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The present study was carried out to evaluate the antidiabetic effect of T. arjuna stembark extract and to study the activities
of hexokinase, aldolase and phosphoglucoisomerase, and gluconeogenic enzymes such as glucose-6-phosphatase and fructose-1,6-diphosphatase
in liver and kidney of normal and alloxan induced diabetic rats. Oral administration of ethanolic extract of bark (250 and
500mg/kg body weight) for 30 days, resulted in significant decrease of blood glucose from 302.67±22.35 to 82.50±04.72 and
in a decrease in the activities of glucose-6-phosphatase, fructose-1,6-disphosphatase, aldolase and an increase in the activity
of phosphoglucoisomerase and hexokinase in tissues. However, in the case of 250 mg/kg body weight of extract, less activity
was observed. The study clearly shows that the bark extract ofT. arjuna possesses potent antidiabetic activity. 相似文献
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《European Journal of Sport Science》2013,13(1):27-33
Abstract In this study, we examined indirect markers of muscle damage and muscle soreness following a 50-km cross-country ski race completed in 2 h and 57 min to 5 h and 9 min by 11 moderately trained male university students. Maximal strength of the knee extensors, several blood markers of muscle damage and inflammation, and muscle soreness (visual analog scale: 0 = “no pain”, 50 mm = “unbearably painful”) were measured one day before, immediately after, and 24, 48, 72, and 144 h after the race. Changes in the measures over time were analysed using one-way repeated-measures analysis of variance and a Fisher's post-hoc test. Maximal strength of the knee extensors decreased significantly (P<0.05) immediately after the race (mean ?27%, s=6), but returned to pre-exercise values within 24 h of the race. All blood markers increased significantly (P<0.05) following the race, peaking either immediately (lactate dehydrogenase: 253.7 IU · l?1, s=13.3; myoglobin: 476.4 ng · ml?1, s=85.5) or 24 h after the race (creatine kinase: 848.0 IU · l?1, s=151.9; glumatic oxaloacetic transaminase: 44.3 IU · l?1, s=4.2; aldolase: 10.0 IU · l?1, s=1.3; C-reactive protein: 0.36 IU · l?1, s=0.08). Muscle soreness developed in the leg, arm, shoulder, back, and abdomen muscles immediately after the race (10–30 mm), but decreased after 24 h (<15 mm), and disappeared 48 h after the race. These results suggest that muscle damage induced by a 50-km cross-country ski race is mild and recovery from the race does not take long. 相似文献
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