排序方式： 共有6条查询结果，搜索用时 15 毫秒
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Subir Kumar Das Sukhes Mukherjee Gaurav Pandey V. Balakrishnan D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2009,24(2):155-158
Non-alcoholic fatty liver disease and its more aggressive form, non-alcoholic steatohepatitis are entities that are becoming
more and more interesting to the medical community in general. A total of 93 Non-alcoholic fatty liver disease patients (64
male and 29 female) within the age range between 28 to 63 years were studied. All of them showed elevated alanine aminotransferase
level (104.07 ± 56.04). Aspartate aminotransferase level (58.13 ± 31.96) was elevated more than its normal level in 82% cases
and AST to ALT ratio was found 0.59 ± 0.26. Predisposing factors were diabetes mellitus (37%), obesity (13%) and hyperlipidemia
(41%). In addition, 32% of the subjects were overweight.18% of the patients had elevated serum bilirubin. Our findings recommend
a lower cutoff value than suggested by the World Health Organization for overweight and obesity among this racial-ethnic group. 相似文献
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Pathogens, especially Gram-negative bacteria or bacterial endotoxin, along with other classical factors, may be involved in
inflammatory response within the aortic endothelium during the progression of cardiovascular disease. Studies have shown that
bacterial endotoxin activates various inflammatory processes in the body. Our study aims to establish a correlation between
endotoxemia and vascular expression of antioxidant enzymes. Swiss albino mice (4 weeks old) were fed a high fat diet for 24
weeks and then were administered Escherichia coli endotoxin intraperitonealy, for 4 weeks. Tissue antioxidant enzymes, serum
levels of IL-6 and TNF alpha were measured from the mice. We report that i.p. administration of endotoxin to hyperlipidemic
mice resulted in elevation of superoxide dismutase and catalase enzymes, which was paralleled by a systemic reduction of serum
cholesterol and LDL expression. Myeloperoxidase levels were also found to be elevated in aortic tissue, while an increase
was also observed in the serum cytokine levels. 相似文献
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Priyanka Surana Aarti Sankhla P. K. Dashora 《Indian journal of clinical biochemistry : IJCB》2000,15(2):167-170
To examine the effect of “DeepaniyaVati”, a herbal formulation in the management of hyperlipidemia, a randomized group pre-test
post-test study trial was carried out on fifty male (30 to 70 yrs) hyperlipidemic volunteers who were asked to follow their
normal routine diet and activity pattern throughout the investigation period. The formulation, prepared by mixing nine plant
products in equal proportion, when given in a daily dose of 2g, twice a day for a period of one month, brought about an observable
improvement in all the lipid parameters by significantly reducing total cholesterol (10%), low density lipoprotein cholesterol
(12.76%), very low density lipoprotein cholesterol (27.4%), triglycerides (34.7%) and bringing these values much nearer to
the normal levels. In control group, no such effect was noticed. A concomitant significant increase in the HDL-C levels suggests
the possible utility of “Deepaniya Vati” in the management of hyperlipidemia and the need for further detailed study. 相似文献
4.
A. Jain P. Goyal P. K. Nigam H. Gurbaksh R. C. Sharma 《Indian journal of clinical biochemistry : IJCB》2007,22(2):151-153
Xanthelasma Palpebrarum is the most common of the xanthomas with asymptomatic, symmetrical, bilateral, soft, yellow, velvety,
polygonal papules around the eyelids. Xanthelasmas may be associated with hyperlipidemia. This prospective study included
66 clinically diagnosed patients with Xanthelasma Palpebrarum and 50 controls with non-inflammatory skin disorders. Serum
triglyceride, cholesterol, HDL, LDL and VLDL estimated in all cases indicated that patients with Xanthelasma Palpebrarum have
underlying lipid abnormalities. 相似文献
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4mg and 8mg monosodium glutamate per gram body weight was administered subcutaneously for 6 consecutive days to normal adult
male mice and its effect was seen on 31st day after the last injection on some antioxidant enzymes in heart. A significant dose dependent increase in lipid peroxidation
and xanthine oxidase level was observed, whereas the activity of free radical scavenging enzymes such as superoxide dismutase
and catalase was decreased in both monosodium glutamate treated groups (Group-2 and Group-3). So, the present work suggested
that monosodium glutamate at dose level of 4mg/g body weight and above induced oxidative stress in the cardiac tissue by changing
the activity of free radical initiating enzyme such as xanthine oxidase and scavenging enzymes like superoxide dismutase and
catalase. 相似文献
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目的:采用循证体育学和循证运动医学的学术思维,对高血脂进行循证研究,归纳高血脂的治疗方法,探索各种形式的运动、饮食、运动联合饮食分别对于高血脂的治疗效果,并分析高血脂分子层面产生的原因及饮食和运动对于血浆环境的改变。和当前治疗高血脂过程中存在的问题,以为临床治疗提供参考并加大对高血脂危害的宣传。方法:以电子方式检索万方、中国知网和维普中文数据库的研究文献,检索时间为从建库至2020年3月。检索词汇:运动、饮食、高血脂。结果及结论:经过筛选,共纳入67篇文献。有氧运动联合饮食对于高血脂及其他慢性疾病的干预不仅可以克服药物的副作用还可以减少家庭负担提高生活质量,值得大范围推广。 相似文献
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