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人体内脂肪酸(FFA)与糖相比具有贮量大、单位质量贮能高等特点，是长时间运动的理想能源。研究认为有氧训练可以提高骨骼肌对脂肪的氧化能力。但有关脂肪的研究远没有对糖的研究那样深入与广泛。本文结合近来的有关脂肪代谢的研究成果从脂肪组织的脂解和FFA的运输、FFA跨肌肉细胞膜的运转、FFA跨线粒体膜的运转、肌肉中甘油三酯(IMTG)的动用4个方面作几点探讨，旨在对运动与脂肪代谢的研究做一点贡献。 相似文献
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目的:观察中药饮品对大鼠生化、形态学和细胞凋亡指标的影响,以期为中药饮品的功效提供新的理论支持和科学数据。方法:SD大鼠48只分为4组,正常对照组、运动疲劳模型组、实验一组、实验二组。除对照组以外、余三组均进行运动跑台训练。实验组中药饮品灌胃。运动结束后,大鼠取骨骼肌检测。结论:两种中药饮品能够有效降低降低骨骼肌中的MDA含量,增加骨骼肌的总抗氧化能力。增加大鼠海马的总抗氧化能力,减少MDA含量。阻止caspase-3的活化,最终达到对抗细胞凋亡的目的。 相似文献
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Harleen Mangat Tajamul Hussain C Sundaram MP JS Anandaraj 《Indian journal of clinical biochemistry : IJCB》2002,17(2):74-79
Poly A RNA status and itsin vitro translation in a rabbit reticulolysate cell free system, were assessed in the skeletal muscle of young boys with Duchenne
muscular dystrophy. Compared to normals there is a significant 48% increase in poly A RNA content of dystrophic muscle and
its translatability was increased by 56% based on35S methionine incorporation into total protein systhesised. Immunoprecipitation of the translated products with monospecific
antibodies showed that there is a 2.6 fold and a 2 fold increase in m and μ calpains respectively. This underlines the importance
of both synthetic and degenerative activities in the early pathology in DMD muscle. 相似文献
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Intentional burns represent a serious form of physical abuse that must be identified to protect children from further harm. This study is a retrospectively planned secondary analysis of the Examining Siblings To Recognize Abuse (ExSTRA) network data. Our objective was to describe the characteristics of burns injuries in children referred to Child Abuse Pediatricians (CAPs) in relation to the perceived likelihood of abuse. We furthermore compare the extent of diagnostic investigations undertaken in children referred to CAPs for burn injuries with those referred for other reasons. Within this dataset, 7% (215/2890) of children had burns. Children with burns were older than children with other injuries (median age 20 months vs. 10 months). Physical abuse was perceived as likely in 40.9% (88) and unlikely in 59.1% (127). Scalds accounted for 52.6% (113) and contact burns for 27.6% (60). Several characteristics of the history and burn injury were associated with a significantly higher perceived likelihood of abuse, including children with reported inflicted injury, absent or inadequate explanation, hot water as agent, immersion scald, a bilateral/symmetric burn pattern, total body surface area ≥10%, full thickness burns, and co-existent injuries. The rates of diagnostic testing were significantly lower in children with burns than other injuries, yet the yield of skeletal survey and hepatic transaminases testing were comparable between the two groups. This would imply that children referred to CAPs for burns warrant the same level of comprehensive investigations as those referred for other reasons. 相似文献
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生物学年龄与运动员生长发育鉴定 总被引：1，自引：0，他引：1
运动员生长发育鉴定在运动员科学选材中十分重要,而生物学年龄的鉴定又是运动员生长发育鉴定的关键.本文综合文献与选材工作经验,详细介绍了几种常用的生物学年龄:骨龄与第二性征是目前运动员生长发育鉴定中常用的方法;牙龄在运动员选材中应用较少,主要受技术和方法等条件的限制,需进一步探索,增加应用的可行性;端粒DNA长度、线粒体DNA损伤和DNA甲基化水平等分子生物学方法推断年龄是比较新的方法,在运动员科学选材领域尚未得到验证与应用.最后本文展望了运动员生长发育鉴定中生物学年龄发展的前景. 相似文献
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过度负荷后产生的骨骼肌损伤及延迟性酸痛一直是当前体育科研中的重要问题。本文对近二十年来的临床治疗和科研成果进行综述,目的在于提高对骨骼肌损伤和延迟性酸痛的治疗及机制的认识。 相似文献
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骨骼肌纤维类型在不同的条件下的转化研究 总被引：3，自引：0，他引：3
随着研究条件与相关技术的发展,近年来科研人员对骨骼肌纤维类型进行了大量的细胞与分子生物学水平的研究。研究发现,除发育因素外,神经支配,运动训练,负荷或去负荷,激素以及衰老等各种因素均对骨骼肌纤维的特异蛋白质表达产生影响,乃至改变肌纤维的种类和肌肉的肌纤维组成。对于成体已发育成熟的骨骼肌来说,在此情况下无论是何种因素引起的肌纤维转化,似乎都与神经支配和神经-肌肉或神经-内分泌活动的变化有关。目前对骨骼肌纤维转化的机理存在多种解释,其中以Chin等根据对成肌细胞培养的研究结果率先提出"骨骼肌特异纤维类型基因表达受钙调神经磷酸酶(calcineurin)依赖性转录信号途径(signaling pathway)控制"这一学说为代表。但是这些理论都不成熟,对骨骼肌纤维转化的机制还需要进一步研究。 相似文献
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骨骼肌缺血再灌注损伤机制及其防治进展 总被引：1，自引：0，他引：1
本文综述了骨骼肌缺血再灌注损伤的机制和防治进展。认为缺血再灌注损伤不仅与自由基、钙超载和白细胞等因素相关,而且细胞凋亡和一氧化氮等因素同样是其重要的致病环节;其防治策略包括缺血预处理和抗氧化等措施,并不断有新方法被发现并应用于临床。缺血再灌注损伤与多种临床疾病及运动损伤密切相关,探讨骨骼朋缺血再灌注损伤的机制对再灌注损伤的预防和处理及骨骼肌功能的恢复具有重要的实践意义。 相似文献