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1.
本文报告 12例糖尿病性动眼神经麻痹,男8例,女4例;累及右眼7例,左眼5例;均为单侧动眼神经不全麻痹。7例空腹血糖高于正常,5例血糖正常者,糖耐量试验均异常。影像学检查未发现颅内动脉瘤,脑干未见异常。治疗在控制糖尿病的同时,辅以大量维生素B族及血管扩张剂,部分病例取得了满意效果,结合文献对其诊断和发病机理进行了分析。  相似文献   

2.
老年肺炎96例临床分析   总被引:1,自引:0,他引:1  
目的:探讨老年肺炎的临床特点,减少临床误诊率,提高老年肺炎的诊疗水平.方法:对2008年1月~2010年1月住德州市人民医院资料完整的96例65岁以上肺炎病例进行回顾性分析.结果:既往有慢性心,肺疾病,脑血管病,糖尿病等基础病及高龄者发病多,发病以冬春季节为多.临床症状:约2/3患者有发热、咳嗽、咳痰等呼吸道症状,1/3的患者以非呼吸道症状为首发症状.47%有心力衰竭、呼吸衰竭、电解质紊乱等并发症.痰培养显示革兰氏阴性杆菌多,双肺CT及X线检查以双肺小片状渗出影多见.结论:正确认识老年肺炎的临床特点,做出早期诊断和治疗,提高治愈率,降低死亡率.  相似文献   

3.
急性心肌梗塞(AMI)是指冠状动脉粥样硬化的基础上,冠脉突然闭塞引起心肌不可逆损伤、坏死所致一种临床综合征,其典型的临床症状是持续性心前区绞痛伴有压榨、窒息感,含服硝酸酯类药物不能缓解。老年性AMI上述症状不明显或缺如,常以突发性晕厥、脉缓和低血压为首发表现,而易误诊为脑血管疾病延误诊治。现将1984.1~1999.4月以晕厥为首发症  相似文献   

4.
目的:探讨老年糖尿病特点及其诊断方法,提出临床医生在诊治中应提高警惕性,减少漏诊和误诊。方法:自2005年1月~2006年4月共收集17例老年糖尿病并发症入院资料。结果:3例病人分别因心肌梗塞、肾功衰及高渗性昏迷死亡,其余患者经积极治疗,并发症及血糖控制好,出院。结论:老年2型糖尿病患者合并症多,容易漏诊和误诊。医生应提高警惕性,重视对OGTT及餐后血糖的监测。  相似文献   

5.
《中国科技奖励》2012,(3):51-51
自身免疫糖尿病约占糖尿病患者总数的10.15%,根据发病缓急可分为急性发病的经典1型糖尿病(T1DM)和缓慢发病的成人隐匿性自身免疫糖尿病(LADA)。其中,LADA的早期临床表现酷似2型糖尿病,极易被误诊而延误治疗。  相似文献   

6.
《老年教育》2013,(7):55
老陈患糖尿病已有6年之久。平时用胰岛素,血糖一直较平稳。近日因头昏乏力到医院检查,结果为低血钾。经医生解释,老陈才恍然大悟,竟是因为天热锻炼大量岀汗所致。体内钾的主要作用是维持酸碱平衡,参与能量代谢,维持神经肌肉正常功能。夏季炎热,人体汗多,导致大量的钾随汗液排出。当体内缺钾时,会造成全身乏力、心跳减弱、头昏眼花,严重缺钾还会导致呼吸肌麻痹而死亡。此外,低钾会使胃肠蠕动减慢,导致肠麻痹,加重厌食,出现恶心、呕吐、腹胀等症状。低钾症状还会引起糖耐量减低,导致血糖不易控制。因此,"糖友"夏季要预防低钾血症。  相似文献   

7.
目的:探讨老年性乳腺导管内乳头状瘤病的发病特点、诊断以及治疗方法。方法:对16例术前诊断为乳腺癌的老年患者,手术后病理证实的乳头状瘤病的病例进行回顾性分析和总结。结果:本组16例均以乳腺肿块为首发症状,其中2例既往有乳头溢液病史,16例术前均行彩超及乳腺钼靶摄片检查,考虑乳腺占位、癌可能性大。术后病理均诊断为乳头状瘤病,其中9例伴不典型增生。结论:老年性乳腺导管内乳头状瘤病最常见症状为乳腺肿块,术前行乳腺彩超及乳腺钼靶检查确诊率较低,仍需要术中行快速冰冻病理检查以明确诊断指导手术及治疗。乳腺导管内乳头状瘤病具有一定的恶变倾向。  相似文献   

8.
以双下肢无力为首发症状就诊,较长时间误诊,进一步检查确诊为肺癌的5例患者,其临床表现缺乏呼吸系统症状,为避免误诊,应行必要的辅助检查及详细询问病史。  相似文献   

9.
本文探讨了60岁及以上女性乳腺癌的临床特点,分析了近年来老年乳腺癌患者48例,本文提示腋窝淋巴转移率为64.6%,老年患者诊治往往延误。腋窝淋巴结阳性疗效较差,临床应注意加强综合治疗。  相似文献   

10.
糖尿病是引发冠心病六大易患因素之一,而且更具有独立危险性。近年随着糖尿病治疗方法的改进,糖尿病酮症的病死率已有明显下降,而急性心肌梗塞已成为中、老年糖尿病者的严重心血管并发病之一。本文对我院1992—1995年收治的122例急性心肌梗塞患者,其中伴糖尿病29例,非糖尿病急性心肌梗塞患者93例,比较临床表现与转归,探讨糖尿病合并急性心肌便死患者的临床与预后特点。 1 资料与方法 全部病例共122例均经酶学心电图检查  相似文献   

11.
Carvedilol protected diabetic rat hearts via reducing oxidative stress   总被引:1,自引:0,他引:1  
INTRODUCTION Diabetes is the largest morbidity of patients with heart failure and adversely affects outcomes of car- diovascular diseases (Beller, 2001). Oxidative stress has been associated with the pathogenesis of chronic diabetic complications including cardiomyopathy (Cai and Kang, 2003). The ability of antioxidants to inhibit these injuries has raised the possibility of newer therapeutic treatment for diabetic heart dis- eases. Recently, Bcl-2 gene has been focused because it was in…  相似文献   

12.
Diabetic nephropathy (DN) is currently the most common complication of diabetes. It is considered to be one of the leading causes of end-stage renal disease (ESRD) and affects many diabetic patients. The pathogenesis of DN is extremely complex and has not yet been clarified; however, in recent years, increasing evidence has shown the important role of innate immunity in DN pathogenesis. Pattern recognition receptors (PRRs) are important components of the innate immune system and have a significant impact on the occurrence and development of DN. In this review, we classify PRRs into secretory, endocytic, and signal transduction PRRs according to the relationship between the PRRs and subcellular compartments. PRRs can recognize related pathogen-associated molecular patterns (PAMPs) and danger-associated molecular patterns (DAMPs), thus triggering a series of inflammatory responses, promoting renal fibrosis, and finally causing renal impairment. In this review, we describe the proposed role of each type of PRRs in the development and progression of DN.  相似文献   

13.
目的:研究动眼神经海面窦段及面听神经桥脑小脑角段显微血管供应。方法:采用大体解剖法显露并观测了40侧动眼、面听神经动脉来源。结果:80%的脑膜垂体干及海面窦下动脉发出滋养动脉至动眼神经;面神经桥小脑角段主要由小脑下前动脉发出的迷路动脉、回返穿通动脉供应。结论:动眼、面听神经毗邻结构复杂,滋养血管细小,手术时应特别注意辨认和保护动眼和面听神经的显微血管。  相似文献   

14.
目的:探讨饮酒后低血糖昏迷的发生机制及诊疗方法。方法:选择我院急诊酒精中毒患者16例,根据其入院时临床表现及低血糖程度,给予高糖及纳洛酮静滴,观察患者治疗后的症状及血糖改善的变化。结果:经过2h治疗后所有患者症状均有明显的改善,昏迷患者意识逐渐恢复,心悸,震颤,出汗等症状好转,复查血糖在4.4~6.2mmol/L后出院。结论:空腹及有肝病史患者在大量饮酒后易出现低血糖表现,发病机制是酒精在肝脏内代谢,可抑制糖异生引起低血糖;此外,饮酒后乙醇可刺激胰岛素分泌增加导致低血糖发生。同时,需要注意与醉酒症状及脑血管病相鉴别。  相似文献   

15.
Very preterm birth is associated with attention deficits that interfere with academic performance. A better understanding of attention processes is necessary to support very preterm born children. This study examined voluntary and involuntary attentional control in very preterm born adolescents by measuring saccadic eye movements. Additionally, these control processes were related to symptoms of inattention, intelligence, and academic performance. Participants included 47 very preterm and 61 full-term born 13-years-old adolescents. Oculomotor control was assessed using the antisaccade and oculomotor capture paradigm. Very preterm born adolescents showed deficits in antisaccade but not in oculomotor capture performance, indicating impairments in voluntary but not involuntary attentional control. These impairments mediated the relation between very preterm birth and inattention, intelligence, and academic performance.  相似文献   

16.
目的:分析尿微量白蛋白与糖尿病早期肾脏损害的关系。方法:测定尿微量采用快速金标法。结果:116例2型糖尿病病人早期尿微量白蛋白检出61例,阳性率占52.5%,结论:尿微量白蛋白检测对糖尿病人早期肾损害诊断有较重要的临床价值。  相似文献   

17.
Journal of Zhejiang University-SCIENCE B - To investigate the value of optic disc retinal nerve fiber layer (RNFL) thickness in the diagnosis of diabetic peripheral neuropathy (DPN). Ninety...  相似文献   

18.
The diagnosis of extra-pulmonary tuberculosis(TB) seems relatively difficult due to the absence of specific symptoms and signs in patients on peritoneal dialysis or hemodialysis.We report four cases of extra-pulmonary tuberculosis on dialysis,with two cases on peritoneal dialysis and two cases on hemodialysis.The presentations,therapy,and outcomes of TB infection in these patients were reviewed.Otherwise,the English literature published in the PubMed database associating extra-pulmonary tuberculosis on dialysis over the last three decades is reviewed.A total of 61 studies containing 70 cases were included.The most common primary disease was diabetic nephropathy(22.86%,16/70).The peritoneum(31.42%,22/70),bone(21.42%,15/70),and lymph node(20%,14/70) were the most frequently infected.Single organ infection was common(90%,63/70).Fever(58.57%,41/70),pain(35.71%,25/70),and enlarged lymph node(20%,14/70) were the most common symptoms.Biopsy(67.14%,47/70) and culture(40%,28/70) provided most reliable methods for clear diagnosis of tuberculosis.The combined treatment of isoniazid,rifampicin,pyrazinamide,and ethambutol(44.29%,31/70) was the most common therapy.The majority of patients improved(82.86%,58/70);however,12 cases got worse(17.14%),with 10 of them dying(14.29%).Physicians should be aware of the non-specific symptoms and location of infection,and consider tuberculosis in their differential diagnoses in dialysis patients presenting with symptoms such as fever,pain,and weight loss.  相似文献   

19.
基于基因工程技术 ,用PCR法扩增出编码ICA6 9的cDNA片段 ,直接克隆到pSPORT 1质粒上 ,经DNA序列测定 ,插入到GST融合蛋白表达载体 pGEX 2T ,构成重组质粒 p2T ICA6 9,得到的表达产物GST ICA6 9融合蛋白用间接ELISA法检测其免疫原性 .测序结果表明 ,所获PCR产物已正确重组到PGEX 2T表达型质粒中 .重组质粒在原核细胞中表达的融合蛋白具有免疫原性 ,并能应用于Ⅰ型糖尿病病人血清中抗ICA6 9抗体的检测 .所获得的表达产物为重组ICA6 9融合抗原 ,有助于提高Ⅰ型糖尿病的预报率和确诊率 .  相似文献   

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