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1.
目的：探讨NF-кB在肝癌介入治疗后肿瘤组织和癌旁肝细胞中的表达及其变化特点。方法：建立VX2肝癌模型兔59只,分为A组（肝癌组）29只,B组（肝癌经导管肝动脉栓塞介入组）30只、C组（对照组）20只,免疫组化检测各组肝癌及癌旁肝组织中的NF-кB表达。结果：A组肝癌组织与癌旁肝组织NF-κB阳性表达率分别为72.4%（21/29）、37.9%（11/29）,肝癌介入治疗后肝癌组织和癌旁组织NF-κB阳性表达率82.4%（24/30）、60%（18/30）,C组NF-κB阳性表达率为10%（2/20）,各组与对照比较,除A组癌旁肝组织外差异均有统计学意义（P〈0.05）,其余两两比较差异无统计学意义（P〉0.05）。结论：治疗前癌旁组织,其内NF-кB的表达水平尚处于较低水平,介入治疗后的癌旁肝组织的脂肪变性及炎性反应等因素可能会导致NF-κB的表达增加。 相似文献
2.
剖宫产切口瘢痕妊娠的早期诊断及处理 总被引：3，自引：0，他引：3
刘晨 《河北北方学院学报(医学版)》2006,23(3):19-21
目的：探讨剖宫产切口瘢痕妊娠（CSP）的早期诊断及子宫动脉栓塞术在CSP治疗中的应用。方法：分析我院4例CSP的临床表现及诊治经过。结果：4例患者均有剖宫产史，经反复B超和彩色超声确诊CSP，均行子宫动脉栓塞术一次成功。结论：彩色多普勒及B超检查是诊断CSP的主要手段，对判断预后和观察治疗效果有帮助。子宫动脉栓塞术可减少剖宫产切口瘢痕妊娠手术时引起的风险及并发症，有条件的医院应将其作为首选方法。 相似文献
3.
秦俊玲 《襄樊职业技术学院学报》2014,(5):35-36
目的观察子宫动脉栓塞术治疗子宫肌瘤的疗效。方法采用seldinger’s方法作选择性子宫动脉栓塞。结果双侧子宫动脉栓塞可完全阻断子宫肌瘤血供。治疗后随访结果表明,肌瘤均比治疗前缩小,月经周期恢复正常,经量增多、贫血症状均明显改善,总有效率达100%。结论子宫动脉栓塞术治疗子宫肌瘤创伤小,并发症少,治疗效果好,是值得推广应用的好方法。 相似文献
4.
Objective： To discuss possible relationships between class In malocclusion and perioral forces by measuring the pressure from the lips and the tongue of children with class nI malocclusion. Methods： Thirty-one children with class In malocclusion were investigated and their perioral forces were measured at rest and during swallowing under natural head position by a custom-made miniperioral force computer measuring system. Results： The resting pressures exerted on the labial side and palatine side of the upper lett incisor, as well as the labial side and lingual side of the lower lett incisor, were 0 g/cm^2, 0 g/cm^2, 0.57 g/cm^2 and 0.23 g/cm^2, respectively. Correspondingly, the swallowing forces were 2.87 g/cm^2, 5.97 g/cm^2, 4.09 g/cm^2 and 7.89 g/cm^2, respectively. No statistical difference between muscular pressure and gender existed. During swallowing, the lingual forces were significantly higher than the labial forces （P〈0.01）, however, at rest there was no significantly different force between these two sides. Compared to the normal occlusion patients, children with class Ⅲ malocclusion had lower pedoral forces. The upper labial resting forces （P〈0.01）, the lower labial resting forces （P〈0.05） and all the swallowing pressures from the lips and the tongue （P〈0.01） showed statistical differences between the two different occlusion conditions. Meanwhile, no significant difference was found for the resting pressure from the tongue between class Ⅲ malocclusion and normal occlusion. Conclusion： Patients with class Ⅲ malocclusion have lower perioral forces and this muscle hypofunction may be secondary to the spatial relations of the jaws. The findings support the spatial matrix hypothesis. 相似文献
5.
掌浅弓的临床解剖学研究 总被引：4，自引：0，他引：4
目的：为手掌血管损伤的修复重建时寻找浅静脉移植修复掌浅弓提供解剖学基础．方法：对54侧成人掌浅弓的类型、形状、对称性和分支进行观察．结果：掌浅弓分5型即尺动脉型、桡尺动脉型、正中尺动脉型、桡正中尺动脉型、尺动脉掌深弓分支型；以尺动脉型和桡尺动脉型为主，正中尺动脉型、桡正中尺动脉型、尺动脉掌分支型少见；有5种形状，弧线形、单弓形多见，不完全形、鞍形、双弓形少见；左右两侧对称性多见，占55．6％．掌浅弓的分支有3—6条，44例发出小指尺掌侧固有动脉，占81．5％．9例小指尺掌侧固有动脉与第3指掌侧总动脉共干，占16．7％．26例发出3条指掌侧总动脉，占48．1％．26例发出4条指掌侧总动脉，占48．1％．结论：手损伤修复重建掌浅弓时应充分注意掌浅弓的分型、形状、对称性和分支． 相似文献
6.
Objective:To discuss possible relationships between class III malocclusion and perioral forces by measuring the pressure from the lips and the tongue of children with class III malocclusion. Methods:Thirty-one children with class III malocclusion were investigated and their perioral forces were measured at rest and during swallowing under natural head position by a custom-made miniperioral force computer measuring system. Results:The resting pressures exerted on the labial side and palatine side of the upper left incisor, as well as the labial side and lingual side of the lower left incisor, were 0 g/cm2, 0 g/cm2, 0.57 g/cm2 and 0.23 g/cm2, respectively. Correspondingly, the swallowing forces were 2.87 g/cm2, 5.97 g/cm2, 4.09 g/cm2 and 7.89 g/cm2, respectively. No statistical difference between muscular pressure and gender existed. During swallowing, the lingual forces were significantly higher than the labial forces (P<0.01), however, at rest there was no significantly different force between these two sides. Compared to the normal occlusion patients, children with class III malocclusion had lower perioral forces. The upper labial resting forces (P<0.01), the lower labial resting forces (P<0.05) and all the swallowing pressures from the lips and the tongue (P<0.01) showed statistical differences between the two different occlusion conditions. Meanwhile, no significant difference was found for the resting pressure from the tongue between class III malocclusion and normal occlusion. Conclusion:Patients with class III malocclusion have lower perioral forces and this muscle hypofunction may be secondary to the spatial relations of the jaws. The findings support the spatial matrix hypothesis. 相似文献
7.
宫颈鳞癌中耐药标志物HSP27和MT的表达及意义 总被引：1，自引：0，他引：1
目的:探讨子宫颈癌变过程中,耐药标志物热休克蛋白27(heat shock protein 27,HSP27)和金属硫蛋白(metallothionein MT)的表达特点,为指导子宫颈癌患者化疗方案制定和提示预后积累资料.方法:集子宫颈切除及活检标本118例,其中有正常宫颈组织13例;子宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)25例;子宫颈鳞状细胞癌80例.在鳞癌组中高分化鳞癌13例、中分化鳞癌53例、低分化鳞癌14例.以S-P免疫组织化学方法,显示HSP27和MT的表达水平.结果:染色显示细胞核或细胞浆被染呈大小不一,深浅不等的棕黄色颗粒.HSP27在正常宫颈上皮、CIN和宫颈鳞癌中阳性率分别为7.69%、24.00%和46.25%,三组间差异有统计学意义(P＜0.01).在正常宫颈中MT阳性率为7.69%(1/13),CIN中阳性率为28.00%(7/25),在宫颈鳞癌中阳性率为56.25%(45/80),三者间有显著性差异(P＜0.01).HSP27和MT的阳性表达率在不同分化程度的宫颈鳞癌间无显著差异.结论:HSP27和MT在正常宫颈、宫颈上皮内瘤变、宫颈鳞癌的阳性表达率逐渐升高(P＜0.01).HSP27和MT的过度表达可分别或联合作为临床上早期诊断宫颈癌或判断CIN预后的参考指标. 相似文献
8.
本文对50例次经导管肝动脉化疗栓塞(TAE)治疗肝癌的并发症及其防治进行了分析。全部病例在TAE术后均有消化道症状,术后血清胆红质、尿素氮、丙氨酸氨基转移酶(ALT)和天门冬酸氨基转移酶(AST)均较术前有不同程度增高,重复化疗栓塞者易出现急性糜烂性胃炎,少见并发症有胆囊梗死、胸腔积液等。笔者还对部分并发症的防治进行了探讨。 相似文献
9.
目的:探讨川崎病(KD)早期诊断要点与减少心血管损伤的治疗方法.方法:对86例确诊KD的住院患儿的临床特点、实验室检查、心电图及超声心动图进行检查,对定期随访结果进行分析.结果:临床特点中肛周红与卡瘢红发生率分别为53.4%、40.7%;超声心动图检查发现冠状动脉扩张28例,冠状动脉瘤5例;用静脉丙种球蛋白(IVIG)治疗的冠状动脉病变发生率33.3%,仅用阿司匹林治疗的冠状动脉病变发生率64.2%,7d内使用IVIG治疗的冠状动脉病变发生率9.6%(P＜0.01).结论:对非典型KD应及时做超声心动图检查,早期足量使用IVIG可减少KD并发冠状动脉病变的发生. 相似文献
10.
童柏荣 《湖南第一师范学报》2005,5(2):15-18
毛泽东著作不仅富有深刻的思想性，而且富有语言的艺术性。毛泽东的语言艺术主要表现在其深邃的思想性、生动的形象性、严密的逻辑性、通俗的大众性和鲜活的创新性等五个方面。它是民族语言宝库中的瑰宝，是语言运用的范例。研究和学习毛泽东著作的语言艺术，必定能帮助我们提高语言表达水平。 相似文献
11.
目的探讨肺和食道鳞状细胞癌中P27基因蛋白的表达状况.方法收集手术切除鳞癌标本63例,10%中性甲醛固定,石蜡切片,厚度5μm.超敏型S-P免疫组织化学染色.结果P27在鳞状细胞癌中总阳性率39.68%,在肺和食道中阳性率分别为36.00%和42.15%.在高、中分化组阳性率为36.00%,低分化组阳性率为53.85%.结论鳞癌组织中P27阳性表达与分化程度及是否转移的相关性有深入研究的必要. 相似文献
12.
目的:探索新生儿惊厥的病因,临床特点和治疗方法.方法:对我院最近6年96例住院新生儿惊厥患者的临床资料,治疗措施的有效性进行分析总结.结果:新生儿惊厥病因最多见的是新生儿缺氧缺血性脑病45例(46.87%),其次是颅内出血18例(18.75%),低钙惊厥12例(12.5%),此三种病因占全部病例的78%以上.结论:减少新生儿惊厥发生的关键是做好围产期保健,提高治愈率的方法是快速止惊,纠正缺氧,尽早病因治疗. 相似文献
13.
翟应增 《楚雄师范学院学报》2006,21(1):47-50
艺术语言以符号化的方式传递人的情感,由于人类情感的模糊性和不确定性,就必须将抽象的情感加以感性显现。艺术语言传情的感性形式是“语象”,它是用以表情的语言单位,是“心象”与一定的语言物质材料(语音或文字)结合而表现出来的一定的语言形式,也是语言表象。语象具有特定的语言形式和系统结构:语象语言表现形式的多样性和层级性。语象是表象化的语言符号:1.所指表象化———语词由概念还原为表象,使抽象的情感变得具体形象;2.所指意蕴化———语象语义内涵是感性和理性、具象和抽象、思想和情感的结合,其语义信息是多元复合的;3.所指赋值化———为语词增添新值,不断赋予语词以具体的、临时的、附加的、新颖的、多方面的含义。 相似文献
14.
INTRODUCTION Pulmonary hypertension is not rare in humanwith some heart and lung diseases. Chronic pul-monary hypertension leads to structural alterationsof the lung vessels. The pathophysiology of thisremodeling process is still poorly understood.Furthermore, the structural damage of the lungvessels limits the clinical success of vasodilatortreatment. Assuming genetic susceptibility, shearstress and inflammation are the principal pathoge-netic factors involved in lung vessel remode… 相似文献
15.
目的：探讨经颅多普勒与彩色多普勒超声联合检查头臂型大动脉炎的价值。方法：应用彩超和TCD检查7例头臂型大动脉炎患者的颅内和颅外动脉．分析二维及血流动力学指标。结果：头臂型大动脉炎病变多位于颅外动脉起始段或近心端（84％）；颅外段动脉狭窄程度与颅内动脉流速呈大致负相关；结论：彩超与TCD联合检查头臂型大动脉炎，对于了解动脉炎所致血管狭窄的分布情况及分析颅外动脉狭窄或闭塞对颅内循环的影响具有重要诊断价值。 相似文献
16.
Zhi-yu Li Bin Li Yu-lian Wu Qiu-ping Xie 《Journal of Zhejiang University. Science. B》2013,14(6):549-554
Left-sided portal hypertension (LSPH) followed by acute pancreatitis is a rare condition with most patients being asymptomatic. In cases where gastrointestinal (GI) bleeding is present, however, the condition is more complicated and the mortality is very high because of the difficulty in diagnosing and selecting optimal treatment. A successfully treated case with severe GI bleeding by transcatheter splenic artery embolization is reported in this article. The patient exhibited severe uncontrollable GI bleeding and was confirmed as gastric varices secondary to LSPH by enhanced computed tomography (CT) scan and CT-angiography. After embolization, the bleeding stopped and stabilized for the entire follow-up period without any severe complications. In conclusion, embolization of the splenic artery is a simple, safe, and effective method of controlling gastric variceal bleeding caused by LSPH in acute pancreatitis. 相似文献
17.
目的观察糖皮质激素联合免疫抑制剂治疗多发性大动脉炎疗效。方法回顾性分析襄阳市襄州区人民医院收治的6例多发性大动脉炎诊断治疗情况。结果 2例病情缓解,包括临床症状缓解或消失,ESR和CRP恢复正常,病情缓解后激素减量维持;1例出现病情复发,复发后联合细胞毒药物及激素治疗,糖皮质激素自始起量开始,病情得到控制;3例患者动脉狭窄严重的行介入治疗后给予小剂量激素维持治疗。结论多发性大动脉炎由于病因不明,早期无特异性症状,早期诊断较困难;确诊后,用糖皮质激素联合免疫抑制剂治疗,对于无严重动脉狭窄的患者能较好地改善症状。 相似文献
18.
目的:探讨HSP_(27)在消化道癌中的表达状况和意义。方法:收集食道癌、胃癌和大肠癌标本168例,用SP免疫组织化学方法染色。结果:HSP在食道癌、胃癌和大肠癌中的表达率分别为66.04％、37.04％和34.43％;在食道癌中高分化组阳性率(75％)明显高于低分化组(38.46％)。HSP表达与性别、年龄、癌侵润深度、淋巴有无转移的相关性不显著。结论:HSP在食道、胃、大肠癌中表达率依次下降,HSP表达率与癌分化程度有一定相关性。 相似文献
19.
目的:探讨P_(53)、Bcl-2基因蛋白在大肠癌中的表达及临床病理联系。方法:对88例大肠癌手术切除标本进行石蜡切片SP法免疫组织化学染色。结果:P_(53)、Bcl-2基因在大肠癌组织中表达率分别为55.68％(49/88)、63.63％(56/88),癌旁移行区粘膜上皮及腺体P_(53)、Bcl-2阳性表达率分别为3.12％(2/64)、31.25％(20/64),二者均有显著性差异(P<0.01)。P_(53)与大肠癌浸润深度有关(P<0.05),而与组织学类型、分化程度、有无淋巴结转移关系不显著(P>0.05)。Bcl-2的表达率在无淋巴结转移大肠原发癌中高于有淋巴结转移的大肠原发癌(P<0.01)。而在淋巴结转移癌组织中Bcl-2表达率高于原发癌组织Bcl-2表达率,差异有显著性(P<0.05)。结论:P_(53)、Bcl-2在大肠癌组织中均有高表达,可能与细胞恶变有密切关系,P_(53)与大肠癌浸润进展有关,与其它生物学行为关系不大;Bcl-2在大肠癌无淋巴结转移前有高表达,在淋巴结转移癌中的表达高于原发癌,提示Bcl-2的表达参与大肠癌转移的形成。 相似文献
20.
目的探讨老年人牙隐裂综合治疗的临床效果及其影响因素。方法根据临床表现及检查,78颗牙隐裂分为早期牙隐裂26颗和晚期牙隐裂52颗,进行综合治疗,治疗后追踪观察2年,分析疗效。结果综合治疗牙隐裂成功率达92％。结论综合治疗是老年人牙隐裂较理想的治疗方法。 相似文献