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1.
目的:观察分析米非司酮并冰水囊和米索前列醇用于中期妊娠引产之效果与副反应。方法:米非司酮25mg,每日早6点服药,2h后进食,晚饭后2h服药,连服三天后行冰水囊引产。24h取出水囊未分娩者后穹窿放入米索前列醇0.2mg,并与雷凡诺羊膜腔内引产对照。结果:米非司酮并冰水囊引产一次成功率100%。79%24h内自然分娩,21%后穹窿放米索前列醇后分娩。米非司酮组宫缩开始时间平均为2.5h,雷凡诺平均为6(4/15)h,总平均时间分别为20(1/6)、40(1/3)h,产后出血平均分别为80.6ml,120.2ml,胎盘胎膜残留刮宫者6%、84%,米非司酮组服药后12%有轻微恶心,雷凡诺40%有低烧,分娩后好转。结论:米非司酮并冰水囊引产必要时加米索前列醇缩短了产程,减少并发症,提高了引产率,为安全、有效的方法之一。  相似文献   

2.
目的探索米非司酮配伍米索前列醇(米索)终止10-16周妊娠有效剂量和给药途径.方法将371妊娠10-16周的健康妇女,随机分成3种不同的治疗组.A组120例,米非司酮25mg Bid×2天,第3天晨口服米索0.6mg,每4-5小时重复1次,最多3次;B组115例,米非司酮100mg Qd×2天,第3天晨口服米索0.6mg,4-5小时后阴道放置米索0.2mg,最多2次;C组136例,米非司酮50mg Bid×2天,第3天晨阴道放置米索0.6mg,每12小时重复1次,最多2次.结果3组24小时内流产成功率分别为87.5%、88.7%、94.1%,C组成功率明显高于A组和B组(p<0.05).胃肠道副反应也明显降低(p<0.05).结论口服米非司酮200mg合并首次阴道放置米索0.6mg是终止10-16周妊娠的良好方法.  相似文献   

3.
目的:探讨术前用米非司酮,乙烯雌酚对依沙吖啶中期妊娠引产的临床效果影响,以减少引产并发症.方法:将150例要求中期妊娠引产的健康妇女随机分为3组,其中Ⅰ组50例,单纯用依沙吖啶引产;Ⅱ组50例,口服米非司酮50mg,bid×2d,第三日行依沙吖啶引产术;Ⅲ组50例,肌注乙烯雌2mg,bid×2d,第3天行依沙吖啶引产术.结果:米非司酮对宫颈的质地、颈管长度和宫口位置有明显的作用,对宫颈有软化和扩张的作用;米非司酮组平均引产时间(注药至分娩时间)为30.80±7.55h,与乙烯雌酚组和对照组比较,有显著性差异(P<0.001);结论:米非司酮作为依沙吖啶中期妊娠引产的术前用药,能明显提高引产的有效性,减少引产并发症发生.  相似文献   

4.
刚刚成立一周的重庆市“青少年意外怀孕救助中心”已经开始向青少年提供帮助。设在重庆市计生医院的这家救助中心2月17日成立,是全国首家为怀孕青少年提供无偿援助的救助中心。中心的援助对象以未婚少女为主。据悉,成立该中心是政府行为而非医院的商业行为。如果少女发生无防护性交事件,一周内均可到这里进行紧急避孕,援助中心将免费提供避孕的药品和器具。少女如果出现意外怀孕,援助中心将免费为少女实施终止妊娠的手术。中心实行保护性医疗,严格保密,充分尊重个人隐私。中心还向那些非意愿发生性行为而怀孕的妇女提供救助。此外,…  相似文献   

5.
[目的]观察妇女妊娠前后血清中氟化物变化.[方法]用离子选择电极,以标准曲线法、标准加入法检测孕妇血清中氟,并与未孕妇女血清进行了比对实验.[结果]本方法线性范围,氟离子浓度0.02-5.0mg/L,r=0.9999,6=59.7,(25℃),检出下限0.012mg/L,孕妇血清和当地未孕妇女血清氟含量分别为0.035±0.006mg/L,0.038±0.008mg/L,P<0.01,具有显著性差异.方法相对标准偏差在5.4%以下,回收率为96%-106%.[结论]本测定方法准确,灵敏,简便;妊娠妇女应注意孕期中的营养补充.  相似文献   

6.
目的:口服米非司酮进行中期妊娠引产,可提高引产的简单性、安全性及减少术后并发症,减轻患者的痛苦及经济负担.方法:选择要求终止中期妊娠的妇女100例,分为用药组和对照组各50例,进行分析、对比.结果:两组均能一次性成功.但用药组出血量及所用时间明显少于对照组,且术后并发症少.结论:本文通过使用利凡诺羊膜腔穿刺与口服米非司酮在中期妊娠引产中的数据对比,分析了米非司酮药物作用和特点,建议临床推广.  相似文献   

7.
目的探讨米非司酮与依沙吖啶联合用于中孕引产效果及其对产程的影响。方法将457例孕16—26周的妇女随机分成两组,观察组227例和对照组230例,观察组经腹壁向羊膜腔内注入依沙吖啶100mg后。空腹分次口服米非司酮最大用药总量为150mg,对照组注药后口服安慰剂,服法同米非司酮。比较两组胎儿胎盘娩出时间、总产程、清宫率、引产成功率及宫颈裂伤发生率、产后出血量。结果观察组自引产开始至胎儿胎盘娩出时间及总产程均较对照组短,宫颈裂伤发生率和清宫率较对照组低,有显著性差异(P〈0.01)。产后出血量少于对照组,但差异无显著性(P〉0.05)。结论两药联合应用减少了引产孕妇的痛苦和住院时间,是一种较好的中期妊娠的引产方法。  相似文献   

8.
目的探讨米非司酮配伍米索前列醇用于终止停经≤49d瘢痕子宫的妊娠。方法晨起空腹服米非司酮75mg,用药第2天早晨空腹服米非司酮75mg;用药第3天来我院空腹口服米索前列醇600μg(3片,200μg/片)门诊观察6h。结论:米非司酮结合米索前列醇用于早孕瘢痕子宫终止妊娠安全有效,值得应用与推广。  相似文献   

9.
目的:探讨终止14~20周妊娠的最佳方法.方法:把孕14~20周要求终止妊娠的健康孕妇随机分为两组,对照组直接羊膜腔内注射利凡诺100 mg,研究组分次口服完200 mg米非司酮后再行羊膜腔内注射.并观察进入产程时间、总产程时间、产后出血量、子宫持续出血时间、胎盘胎膜残留率、清宫率、引产成功率等.结果:研究组比对照组进入产程快,总产程短,产后出血量少,子宫持续出血时间短,胎盘胎膜残留少,清宫率低,差异有显著性.引产成功率差异无显著性.结论:米非司酮配伍利凡诺终止中期妊娠优于单纯使用利凡诺引产,方法简单可行.值得临床推广.  相似文献   

10.
目的:探讨静脉用胺碘酮治疗心力衰竭并阵发性房颤的临床疗效和安全性。方法:将胺碘酮150mg溶于5%葡萄糖20ml中,于10min内缓慢静脉推注,首剂后15-20min未转复为窦性心律,再给予75-150mg静注,继之以0.5-3mg/min持续静脉滴注24h(24h总量少于1500mg)。结果:60例患者中有49例转复为窦性心律,有效率81.7%,心功能平均提高(1.6±0.4)级。不良反应发生率为11.6%,无1例因不良反应而中断治疗。结论:静脉用胺碘酮对心力衰竭并阵发性房颤的临床疗效确切、安全。  相似文献   

11.
目的探讨米非司酮配伍米索前列醇在足月妊娠引产的作用和安全性 ;方法将 6 2例足月妊娠的正常孕妇有引产指征者随机分成两组进行比较。研究组 (31例 )口服米非司酮 2 0 0mg及米索前列醇5 0ug阴道上药 ,每二小时一次至正式临产 ;对照组 (31例 )口服蓖麻油 5 0毫升炒鸡蛋 2个一顿用。结果两组引产总有效率分别为 93.5 %和 75 .1% ,有显著性差异 (P <0 .0 1)。结论应用米非司酮配伍米索前列醇进行足月妊娠引产 ,能促宫颈成熟 ,发动子宫收缩 ,并安全、有效、方便、有临床价值。  相似文献   

12.
The purpose of this study was to investigate Black South African freshmen's experience of first intercourse and contraception. The study found that many students do not use contraception during first intercourse and that peers were reported as the primary first source of learning about sexual intercourse as well as the preferred source. Freshmen who are contemplating, anticipating or deferring the transition from virginity to non-virginity are an important target group for campus safer sex programmes because safer sex behaviours could be encouraged before a high risk sexual behavior pattern develops.  相似文献   

13.
Despite awareness of the growing number of pregnant teens in the US, little information has been published concerning factors that predict early childbirth among individual girls. To begin to address this issue, the influence of specific life and social factors was examined in 50 adolescent girls with documented histories of good and poor contraception use. Patients selected for participation were 50 indigent nulliparous adolescent and young adult females from 14-22 years old receiving health care at the Teen Health Clinic at the Jefferson Davis Hospital in Houston, Texas. 25 adolescents who indicated that they had been able to use oral contraception prescribed by the clinic for at least 6 months without major problems or complaints were classified as good contraceptors. 25 adolescents assigned to the poor contraceptors group were those who missed 2 or more appointments in a 6-month interval, experienced at least one suspected pregnancy during this time, and indicated verbally that they had not been completely compliant. Each subject was assessed with a structured interview consisting of 25 questions on the patient's past history of contraception, school performance, family birth, employment, residence patterns, and accessibility to contraceptive services. Data from each of the 25 questions of the interview were pooled for the good and poor contraceptors. Where applicable, Chi-square frequency tests and t-tests were used to determine whether differences were statistically significant. Some of the results follow. 1) Reasons for occasional nonuse of oral contraception in the 12 months prior to the interview were assessed in both samples; no statistical differences were observed. The majority of nonusers attributed it to a random event, such as a memory lapse. 2) Sources of birth control education were equivalent in the 2 groups. 3) Good contraceptors reported intercourse 2.6 times/month, as compared to 4.7 times/month for poor contraceptors. 4) 3 of 25 good contraceptors had dropped out of school, while 9 out of 25 poor contraceptors had left school. 5) 72% of the good contraceptors intended to complete at least 2 years of college, but only 52% of the poor contraceptors did. 6) Poor contraceptors had a greater frequency of sisters who had become pregnant relative to good contraceptors. 7) Good contraceptors were more likely to be employed either part- or full-time (52%) than were the poor contraceptors (28%). 8) Good contraceptors reported fewer changes in residence relative to the poor contraceptors in the preceding 5 years. 9) Poor contraceptors had significantly longer travel times to the clinic (mean of 54.5 minutes) relative to good contraceptors (mean of 33 minutes).  相似文献   

14.
Abstract This article reports on the conduct and results of a randomised controlled trial to test the effectiveness of a teacher‐led intervention to improve teenagers' knowledge of emergency contraception. The trial was successfully conducted in 24 mixed‐sex state secondary schools in Avon, South‐west England. The intervention was popular with both teachers and pupils, and significantly improved pupils' knowledge of emergency contraception. The article uses the emergency contraception trial to demonstrate the feasibility of conducting large‐scale randomised trials in schools. The article focuses particularly on study design, specification of research question, recruitment of schools and method of randomisation to highlight methodological choices that can maximise the feasibility and value of such trials to answer questions regarding the effectiveness of complex educational interventions. The article also highlights the importance of using theory and mixed research methods both to thoroughly develop an intervention before it is tested in a trial, and also to evaluate factors affecting its success within a trial.  相似文献   

15.
非职业暴露后预防(nPEP)是指包括对性暴露后与静脉药物注射暴露后的预防H IV感染的措施.应该尽可能早的开始(暴露后72 h内),用多种药物联合治疗连续28 d.nPEP中心理咨询也是重要的组成部分.抗逆转录病毒治疗首选2个核苷类逆转录酶抑制剂.相对于职业暴露来说nPEP在预防H IV感染方面没有很好的效果.容易失败的原因主要有:①延时治疗;②非职业暴露者对PEP治疗依从性差;③反复多次发生暴露;④进行肛交是预防H IV感染所面临的一个严峻的问题;⑤不合理的药物组合.  相似文献   

16.
The aim of this study was to examine both positive and negative aspects of relationship quality in relation to condom use. Sexually active young women aged 14–18 years (n = 111; 34% non-white) were recruited from community clinics and schools in the Midwest USA and provided data via an online survey. The number of unprotected sex acts in the past month with the most recent male partner was regressed on relationship quality with that partner, adjusting for demographics and other characteristics. Negative relationship quality was associated with a greater number of unprotected sex acts among women reporting a low level of positive relationship quality and among women taking hormonal/IUD contraception. Positive relationship quality was associated with unprotected sex among women who reported multiple partners in the past month. Both positive and negative aspects of relationship quality may confer risk for unprotected sex. This risk appears to be modified by patterns of contraceptive use and other sexual behaviours. Health professionals and sexual health educators may be more effective in promoting condom use if they ask questions about both positive and negative aspects of young people’s relationship quality and tailor their conversations based on the responses received.  相似文献   

17.
This study demonstrates a method for obtaining data on developmental changes in adolescents' interest in human sexuality. A content analysis was done on a sample of 874 student-generated questions. Question boxes were placed in classrooms so students could anonymously submit questions. In deference to perceived community pressure, questions on abortion, homosexuality, and masturbation were not allowed. Students who wrote the questions are 7th, 8th, and 10th graders enrolled in 13 different public schools. The schools are located in several small communities and on an American Indian reservation in a rural area of northern California. All children who participated did so voluntarily and with parental permission. Of the total 874 questions. 7th and 8th graders provided 593, while sophomores accounted for 233. Gender information was available only for 7th and 8th graders. Boys asked 173 questions while girls asked 241. The data are broken down by gender and by grade (7th and 8th vs. 10th). Findings reveal that younger students show more interest in the meaning of slang terms, their reproductive physiology, and intercourse. Older students show greater interest in contraception and health risks. Males are interested in slang and intercourse while females are more concerned with health risks and communication. One unexpected finding indicates that among younger children, boys and girls are equally interested in birth control and pregnancy; in the lower grades then, may be the prime time to use sex education programs to strengthen the sense of dual responsibility for knowledge about contraception and pregnancy. Also, the relative absence of questions on disallowed issues (2.5%) makes it apparent that sex educators can effectively suppress inquiry into topics that are of great interest to youngsters; only about 1/3 of the students indicated that their parents had discussed these disllowed issues, yet 48% of the students expressed interest in knowing more about abortion.  相似文献   

18.
The purpose of this study was to identify the factors that influence undergraduate college student use of emergency contraception (EC) and their level of knowledge about the product, in order to assist in the development of intervention programmes to increase its use, which could lead to lower rates of unintended pregnancies in this population. A response rate of 98.4% included 1553 surveys from students at 11 Midwestern universities. Students were predominantly female (63.5%), white (75.3%) and aged 18–21 years (80%). They ranged from first-year students (23.8%) through to fourth-year students (13.8%), with second-year students comprising the largest group (32.6%). The majority of respondents reported being heterosexual (92.1%), and 34.1% of those completing the questionnaire reported being in a committed relationship. Most respondents reported having had sexual intercourse at least once in their lifetime (78.9%). Of the 8.4% of sexually active students who had experienced an unintended pregnancy, 18.1% had used EC in the past 12 months. Knowledge of EC was not high; but as knowledge increased, the use of EC increased. The Integrated Behavioural Model predicted 50% of the variance in intention. Each construct contributed a portion of variance except experiential attitude, which was not statistically significant in the path analysis. The model could be used in any future interventions to increase EC use and decrease unintended pregnancies among college students.  相似文献   

19.
8% of all individuals residing in the US have tested positive for infection with HIV. This study reports the use of condoms and others forms of contraception in two samples of students from East Carolina University. 234 students in 1982 taking a course in marriage and family responded to a 32-item questionnaire distributed in five classes on whether they had used contraception during their most recent episode of sexual intercourse and which method they used. 96% of the respondents were never married, 83% white, and 82% middle class. 7% were engaged to be married and 3% were cohabiting. 53.4% were women and in their junior or senior year (52.5%) of undergraduate education. While the sample was not random, it closely approximated the demographic characteristics of the university from which it was drawn. 79.1% reported using some form of contraception, with 61.8% using the pill and 15.3% using the condom. Of those who used a form of contraception, 8.1% reported using withdrawal and 1.5% rhythm. Fifty university students were again sampled in 1992 in a marriage and family class to find 76% reporting use of contraception during their last episode of sexual intercourse. The percentage of students which reported using a condom, however, increased to 39%. These findings add to the body of research literature which suggests that condom use has increased over the past decade. Further research is, however, warranted to determine whether these data reflect an actual increase in condom use or are simply the result of students providing socially desirable answers.  相似文献   

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