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1.
Mandibular defect occurs more frequently in recent years, and clinical repair operations via bone transplantation are difficult
to be further improved due to some intrinsic flaws. Tissue engineering, which is a hot research field of biomedical engineering,
provides a new direction for mandibular defect repair. As the basis and key part of tissue engineering, scaffolds have been
widely and deeply studied in regards to the basic theory, as well as the principle of biomaterial, structure, design, and
fabrication method. However, little research is targeted at tissue regeneration for clinic repair operations. Since mandibular
bone has a special structure, rather than uniform and regular structure in existing studies, a methodology based on tissue
engineering is proposed for mandibular defect repair in this paper. Key steps regarding scaffold digital design, such as external
shape design and internal microstructure design directly based on triangular meshes are discussed in detail. By analyzing
the theoretical model and the measured data from the test parts fabricated by rapid prototyping, the feasibility and effectiveness
of the proposed methodology are properly verified. More works about mechanical and biological improvements need to be done
to promote its clinical application in future. 相似文献
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This paper introduces a technical method by which bone tissue bionic scaffolds are fabricated on a selective laser sintering machine. It also analyses determinative factors in fabricating porous structure using this method, and proposes a new technique to fabricate porous structure by rapid prototyping method. 相似文献
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One approach to the development of software, which has received considerable attention in the software engineering literature, is rapid prototyping. We describe the rapid prototyping methodology and discuss some of its advantages and disadvantages. We then focus on the use of rapid prototyping in the project component of the typical undergraduate software engineering course. Several approaches to prototyping are described, along with various automated tools that support prototyping. Our experiences with prototyping in our undergraduate software engineering course are described, and we draw a number of conclusions vis a vis the use of prototyping. 相似文献
6.
毛文 《中国现代教育装备》2010,(21):47-49
本文阐述了反求工程与正向工程的区别,反求工程的基本概念、常用数据采集方法,以及反求工程在快速成型技术中应用的意义。反求工程与快速成型技术的结合应用,可以快速响应市场需求的变化,为快速成型和快速模具技术的发展开辟新的领域。 相似文献
7.
Rapid prototyping: An alternative instructional design strategy 总被引：1，自引：15，他引：1
Steven D. Tripp Barbara Bichelmeyer 《Educational technology research and development : ETR & D》1990,38(1):31-44
There is a design methodology calledrapid prototyping which has been used successfully in software engineering. Given the similarities between software design and instructional design, we argue that rapid prototyping is a viable model for instructional design, especially for computer-based instruction. Additionally, we argue that recent theories of design offer plausible explanations for the apparent success of rapid prototyping in software design. Such theories also support the notion that rapid prototyping is appropriate for instructional design. We offer guidelines for the use of rapid prototyping and list possible tradeoffs in its application. 相似文献
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3D打印技术也称为快速成型,是一门新兴的技术。其中基于融熔沉积技术的桌面3D打印机应用日益广泛。为了使打印材料牢固的涂覆在打印机工作台表面,需要将一些利于粘附的材料贴附到3D打印机工作台表面。根据不同的打印耗材,应使用不同的贴面材料。文章分析了几种贴面材料的性能,使用方法,适用范围。并以使用PLA （聚乳酸）线材进行3D打印为例,分析了几种工作台贴面材料的优缺点。 相似文献
9.
杨春蓉 《福建工程学院学报》2011,9(3):205-208
通过仿生合成、冷冻干燥及交联处理方法,制备出一种以双相磷酸钙、胶原和碳酸羟基磷灰石三组分为主要成分的新型三维骨组织工程支架。采用SEM、EDX和FTIR等测试技术对支架的性能特征进行分析。结果表明:制备的复合支架具有三维多孔的有序结构。双相磷酸钙作为力学支撑骨架有助于胶原网络基质形成特定的形状并使之具有一定的力学强度。在矿化过程中,羟基磷灰石矿物晶体在胶原的反应成核位点通过化学键合作用进行自组装。交联的胶原及其仿生矿化形成的碳酸羟基磷灰石可使支架具有良好的生物学性能,有望成为广阔临床应用前景的骨组织工程植入材料。 相似文献
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反求设计与快速原型技术在现代制造活动中发挥着越来越重要的作用。以汽车曲面模型为对象,论述了反求设计与快速原型一体化制造的工艺过程、关键技术,为产品的快速创新设计和制造提供新的思路。 相似文献
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Hendrik Dubbe Elena Holl Adriaan Spierings Konrad Wegener Ulrich Nieken 《浙江大学学报(A卷英文版)》2018,19(10):735-745
Examples of the use of additive manufacturing and rapid prototyping in a range of applications are of great interest in order to emphasize their role in development and production technology. In this study, a catalytic low temperature burner for H2 on a lab scale with an integrated flow distributor was designed, manufactured, and tested for functionality. Based on a theoretical approach, a flow distributor for the burner was designed and a prototype was built using fused deposition modeling (FDM). Based on test results, an optimized version of the burner was then designed and manufactured using selective laser melting (SLM). The functionality of the designed catalytic burner was proven. Several advantages were found in comparison to conventional non-catalytic burners. In particular, flameless uniform low temperature heat generation with temperatures of about 200 °C could be realized. This contribution highlights the potential of additive manufacturing in chemical engineering. Not only was the final product built using SLM, but also during the development process, FDM was used for rapid prototyping. 相似文献
12.
Bing Zhang Pei-biao Zhang Zong-liang Wang Zhong-wen Lyu Han Wu 《Journal of Zhejiang University. Science. B》2017,18(11):963-976
Objective
A new therapeutic strategy using nanocomposite scaffolds of grafted hydroxyapatite (g-HA)/poly(lactide-co-glycolide) (PLGA) carried with autologous mesenchymal stem cells (MSCs) and bone morphogenetic protein-2 (BMP-2) was assessed for the therapy of critical bone defects. At the same time, tissue response and in vivo mineralization of tissue-engineered implants were investigated.Methods
A composite scaffold of PLGA and g-HA was fabricated by the solvent casting and particulate-leaching method. The tissue-engineered implants were prepared by seeding the scaffolds with autologous bone marrow MSCs in vitro. Then, mineralization and osteogenesis were observed by intramuscular implantation, as well as the repair of the critical radius defects in rabbits.Results
After eight weeks post-surgery, scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDX) revealed that g-HA/PLGA had a better interface of tissue response and higher mineralization than PLGA. Apatite particles were formed and varied both in macropores and micropores of g-HA/PLGA. Computer radiographs and histological analysis revealed that there were more and more quickly formed new bone formations and better fusion in the bone defect areas of g-HA/PLGA at 2–8 weeks post-surgery. Typical bone synostosis between the implant and bone tissue was found in g-HA/PLGA, while only fibrous tissues formed in PLGA.Conclusions
The incorporation of g-HA mainly improved mineralization and bone formation compared with PLGA. The application of MSCs can enhance bone formation and mineralization in PLGA scaffolds compared with cell-free scaffolds. Furthermore, it can accelerate the absorption of scaffolds compared with composite scaffolds.13.
施祖平 《荆门职业技术学院学报》2009,24(5):9-12
文章介绍了传统Web数据库应用系统的结构,以及它的一些弊端,基于此提出了基于中间件的Web数据库,并介绍了相应的面向对象中间件的主要技术。在此基础上提出了基于CORBA／Java的Web数据库系统改进模型。 相似文献
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采用快速原型控制技术,搭建了一套电液多维力控并联机器人半实物仿真系统。利用该平台进行实验教学,可解决机械工程专业液压控制系统、机械控制工程基础以及机器人技术等课程理论脱离实践的教学难题。结合上述课程的理论知识以及相应工程案例,探索电液多维力控并联机器人在实验教学中的应用和实践。实验结果表明,基于该实验平台的实验教学,增强了研究生对相关理论知识的理解,提高了研究生实践能力,为机电液一体化专业课程教学提供了一种新颖的教学平台。 相似文献
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快速原型法教学设计初探 总被引：3，自引：1，他引：2
近年来,快速原型法成为影响教学设计实践的新方法。它可以有效地缩短教学设计周期,提高产品质量,满足用户和设计者的需求。文章从快速原型法的特点、原型的界定、及其与时间周期的关系等几个方面的分析论述,为在教学设计实践中运用快速原型提供了前提。 相似文献
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制备尖晶石型锰酸锂是降低锂离子电池成本的有效途径.本文将就现有锰酸锂的制备方法和技术问题进行论述,较为详细的分析不同制备方法的特点,指出存在的问题或改进的思路,为锂离子电池新型正极材料-尖晶石型锰酸锂的制备提出一些参考信息. 相似文献
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Fused deposition modelling （FDM） is one of rapid prototyping （RP） technologies which uses an additive fabrication approach.Each commercially available FDM model has different types of process parameters for different applications.Some of the desired parts require excellent surface finish as well as good tolerance.The most common parameters requiring setup are the raster angle,tool path,slice thickness,build orientation,and deposition speed.The purpose of this paper is to discuss the process parameters of FDM Prodigy Plus （Stratasys,Inc.,Eden Prairie,MN,USA）.Various selected parameters were tested and the optimum condition was proposed.The quality of the parts produced was accessed in terms of dimensional accuracy and surface finish.The optimum parameters obtained were then applied in the fabrication of the master pattern prior to silicone rubber moulding （SRM）.These parameters would reduce the post processing time.The dimensional accuracy and surface roughness were analyzed using coordinate measuring machine （CMM） and surface roughness tester,respectively.Based on this study,the recommended parameters will improve the quality of the FDM parts produced in terms of dimensional accuracy and surface roughness for the application of SRM. 相似文献
19.
快速成型技术的应用发展中的问题 总被引：1，自引：0，他引：1
刘晓波 《合肥联合大学学报》2001,11(1):89-92
介绍了快速成型技术(RPT)在新产品开发、模具制作、医疗、艺术等方面的应用，从资源、能源消耗、环境保护和劳动保护等方面阐述了该技术为环保型技术，但该技术在发展中仍然存在一些问题．这将影响它的普及和推广。 相似文献
20.
水泥搅拌桩作为饱和软粘土地基加固处理的一种形式,其施工质量与施工工艺、全桩身质量的有效检测、施工管理水平密切相关。文章对淮河入海水道淤土段穿堤建筑物戴舍涵洞工程中水泥搅拌桩施工工艺的选择进行了研究,以期保证工程质量、提高经济效益。 相似文献