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1.
The resonant column (RC) and cyclic triaxial (CT) devices are commonly used for the measurement of soils’ dynamic properties. The results of these tests do not agree when extrapolated to similar strain levels. The main objectives of this paper are to evaluate the effect of excitation frequency on the dynamic properties of soils, and to provide a methodology to reconcile shear modulus values obtained from RC and CT tests. The effect of frequency on the dynamic properties is evaluated using the new non-resonance (NR) method in the RC device and CT tests. Sand specimens with varying percentages of bentonite-water mixture and a clay specimen are tested. The results obtained from RC tests utilizing the NR method indicate significant change in shear modulus with frequency. The extrapolation of shear modulus from the conventional RC results to shear strains used in CT is significantly overestimated. The extrapolations improved when the results were corrected for frequency effect inferred from the NR method.  相似文献   

2.
This study illustrates design optimization for multiple wind towers located at different villages in Alaska. The towers are supported by two different types of foundations: large mat or deep piles foundations. Initially, a reinforced concrete (RC) mat foundation was proposed. Where soil conditions required it, a pile foundation solution was devised utilizing a 30 in thick RC mat containing an embedded steel grillage of W18 beams and supported by 20-24 in grouted or un-grouted piles. For faster installation and lower construction cost, all-steel foundations were proposed for these remote Alaska sites. The new all-steel design was found to reduce the natural frequencies of the structural system due to softening the foundation. Thus, the tower-foundation system could potentially become near-resonant with the operational frequencies of the wind turbine. Consequently, the likelihood of structural damage or even the collapse is increased.A detailed 3D finite-element model of the tower-foundation-pile system with RC foundation was created using SAP2000. Soil springs were included in the model based on soil properties obtained from the geotechnical investigation. The natural frequency from the model was verified against the tower manufacturer analytical and experimental values. When piles were used, numerous iterations were carried out to eliminate the need for the RC and optimize the design. An optimized design was achieved with enough separation between the natural and operational frequencies. The design successfully avoids damage to the structural system, while eliminating the need for any RC in most cases.  相似文献   

3.
In this work, we developed a novel active fault-tolerant control (FTC) design scheme for a class of nonlinear dynamic systems subjected simultaneously to modelling imperfections, parametric uncertainties and sensor faults. Modelling imperfections and parametric uncertainties are dealt with using an adaptive radial basis function neural network (RBFNN) that estimates the uncertain part of the system dynamics. For sensor fault estimation (FE), a nonlinear observer based on the estimated dynamics is designed. A scheme to estimate sensor faults in real-time using the nonlinear observer and an additional RBFNN is developed. The convergence properties of the RBFNN, used in the fault FE part, are improved by using a sliding surface function. For FTC design, a sliding surface is designed that incorporates the real-time sensor FE. The resulting sliding mode control (SMC) technique-based FTC law uses the estimated dynamics and real-time sensor FE. A double power-reaching law is adopted to design the switching part of the control law to improve the convergence and mitigate the chattering associated with the SMC. The FTC works well in the presence and absence of sensor faults without the requirement for controller reconfiguration. The stability of the proposed active FTC law is proved using the Lyapunov method. The developed scheme is implemented on a nonlinear simulation of an unmanned aerial vehicle (UAV). The results show good performance of the proposed unified FE and the FTC framework.  相似文献   

4.
神经网络在混凝土结构可靠度评估中的应用   总被引:2,自引:0,他引:2  
张苑竹  金伟良 《科技通报》2002,18(6):495-500
由于混凝土结构股役期间大量不确定因素的影响,有时难以利用确定性函数或专家系统计算结构的性能退化。本文利用有限的样本建立并训练BP神经网络,推广出混凝土结构抗力的时变规律,并应用混凝土结构时变可靠度评估中,计算简单,精度高。  相似文献   

5.
Computational design optimization for microfluidic magnetophoresis   总被引:2,自引:0,他引:2  
Current macro- and microfluidic approaches for the isolation of mammalian cells are limited in both efficiency and purity. In order to design a robust platform for the enumeration of a target cell population, high collection efficiencies are required. Additionally, the ability to isolate pure populations with minimal biological perturbation and efficient off-chip recovery will enable subcellular analyses of these cells for applications in personalized medicine. Here, a rational design approach for a simple and efficient device that isolates target cell populations via magnetic tagging is presented. In this work, two magnetophoretic microfluidic device designs are described, with optimized dimensions and operating conditions determined from a force balance equation that considers two dominant and opposing driving forces exerted on a magnetic-particle-tagged cell, namely, magnetic and viscous drag. Quantitative design criteria for an electromagnetic field displacement-based approach are presented, wherein target cells labeled with commercial magnetic microparticles flowing in a central sample stream are shifted laterally into a collection stream. Furthermore, the final device design is constrained to fit on standard rectangular glass coverslip (60 (L)×24 (W)×0.15 (H) mm3) to accommodate small sample volume and point-of-care design considerations. The anticipated performance of the device is examined via a parametric analysis of several key variables within the model. It is observed that minimal currents (<500 mA) are required to generate magnetic fields sufficient to separate cells from the sample streams flowing at rate as high as 7 ml∕h, comparable to the performance of current state-of-the-art magnet-activated cell sorting systems currently used in clinical settings. Experimental validation of the presented model illustrates that a device designed according to the derived rational optimization can effectively isolate (∼100%) a magnetic-particle-tagged cell population from a homogeneous suspension even in a low abundance. Overall, this design analysis provides a rational basis to select the operating conditions, including chamber and wire geometry, flow rates, and applied currents, for a magnetic-microfluidic cell separation device.  相似文献   

6.
[目的/意义]作为健康信息的一种,在线医评信息对用户医疗决策十分重要。研究用户查寻在线医评信息的过程,挖掘存在的障碍,有助于优化医评网站设计、促进医生在线服务和满足用户健康信息查寻需求。[方法/过程]采用检索实验、内容分析、发声思考和问卷调查等方法,从查寻表现、查寻阶段和查寻障碍3个方面分析在线医评信息这一特定情景下用户的查寻行为及存在问题。[结果/结论]结果显示教育水平和健康信息检索技能与在线医评信息查寻表现正向相关。在线医评信息查寻过程模型包括医生初筛、医评信息检索、浏览、对比、验证和利用6个阶段。健康信息检索技能和甄别能力弱、医评网站评论数量少、医院官网和医评网站可用性差以及医评网站与线下医疗服务融合程度低是影响用户查寻在线医评信息的主要障碍。  相似文献   

7.
We report the development and results of a two-step method for sorting cells and small particles in a microfluidic device. This approach uses a single microfluidic channel that has (1) a microfabricated sieve which efficiently focuses particles into a thin stream, followed by (2) a dielectrophoresis (DEP) section consisting of electrodes along the channel walls for efficient continuous sorting based on dielectric properties of the particles. For our demonstration, the device was constructed of polydimethylsiloxane, bonded to a glass surface, and conductive agarose gel electrodes. Gold traces were used to make electrical connections to the conductive gel. The device had several novel features that aided performance of the sorting. These included a sieving structure that performed continuous displacement of particles into a single stream within the microfluidic channel (improving the performance of downstream DEP, and avoiding the need for additional focusing flow inlets), and DEP electrodes that were the full height of the microfluidic walls (“vertical electrodes”), allowing for improved formation and control of electric field gradients in the microfluidic device. The device was used to sort polymer particles and HeLa cells, demonstrating that this unique combination provides improved capability for continuous DEP sorting of particles in a microfluidic device.  相似文献   

8.
A general technique is presented to minimize sensitivity in the design of active RC networks. It is shown that the minimization procedure can be applied to any active RC structure that has degrees of freedom in choosing the design parameters. Since most active RC structures have independent parameters that can be arbitrarily chosen, the applicability of the procedure is quite general. In particular, in this paper the minimization technique is applied to: (1) fixed circuit configurations where the circuit elements are optimally chosen and (2) RC:–RC decomposition, i.e. synthesis procedures that employ an arbitrary polynomial Q(s) where the optimal roots of Q(s) are determined.  相似文献   

9.
Unified modeling and analysis of a proportional valve   总被引:4,自引:0,他引:4  
Developments in nonlinear control theory have made it possible to design controllers for systems having non-smooth nonlinearities in their dynamics. Hydraulic systems that use inexpensive proportional valves are examples of such systems, where nonlinearities arise due to valve geometry and spool imperfections. Without a proper valve model, however, nonlinear analysis and control of these hydraulic systems is not possible.We have developed nonlinear equations for a generic proportional valve model and have used them to obtain simplified flow rate expressions under generally accepted assumptions. These equations relate a set of geometric spool properties and physical model parameters to the flow rate through the valve ports. The development focuses on obtaining a single set of flow rate equations applicable to critical center, overlapped, and underlapped proportional valves. These unified model equations are useful for simulation and nonlinear controller design. We have also demonstrated that the errors incurred when using the unified valve model are dependent on the damping coefficient alone and are less than 10% in the frequency range within which most valves are used.  相似文献   

10.
运用模糊综合评价法,对现有的国防研究所研发人员考核体系进行分析,指出现行考核体系存在的问题,虽然经济指标是明确的,但其他方面的指标是不具体的,没有一个相对量化的、可供监控的考核体系。对其绩效因素进行论证,利用模糊综合评价权数制定国防工业研发人员考核指标体系,从思想品德,工作能力,工作态度,工作成果,自我改进5个方面作为评价指标,对研发人员进行综合评价,同时打分填写5个评级指标子集的权数,并排出重要程度的顺序,得出研发人员绩效评价状况所达到的等级。所得结论能为研究院所的考核提供借鉴。  相似文献   

11.
表层嵌贴FRP加固RC梁新技术   总被引:5,自引:2,他引:3  
王韬  姚谏 《科技通报》2005,21(6):735-740
最近几年来,国外对表层嵌贴FRP复合材料加固混凝土结构这一新技术进行了一系列的试验和理论研究。本文简要论述这一新技术的研究进展,着重论述钢筋混凝土梁加固后的破坏形式和承载力计算方法。供实际工程应用参考。  相似文献   

12.
In this paper, a novel oscillating flow polymerase chain reaction (PCR) device was designed and fabricated to amplify SPPS150 and salmonella typhi. In this new design, the samples are shuttled (oscillating flow) inside a microfluidic chip to three different temperature zones required for DNA amplification. The amplification cycle time has markedly been reduced as the reagent volume used was only about 25% of that used in conventional PCRs. Bubble formation and adsorption issues commonly associated to chip based PCR were also eliminated. Based on the performance evaluated, it is demonstrated that this oscillating flow PCR has the advantages of both the stationary chamber and continuous flow PCR devices.  相似文献   

13.
The paper provides practical means for selecting the optimum parameters for the design of a lossless coupling network that equalizes the parallel RC load to resistive generator and to achieve the nth-order elliptic transducer power-gain characteristic. Fundamental gain-bandwidth limitation and other restrictions are established in their full generality.  相似文献   

14.
Aspect mining, which aims to extract ad hoc aspects from online reviews and predict rating or opinion on each aspect, can satisfy the personalized needs for evaluation of specific aspect on product quality. Recently, with the increase of related research, how to effectively integrate rating and review information has become the key issue for addressing this problem. Considering that matrix factorization is an effective tool for rating prediction and topic modeling is widely used for review processing, it is a natural idea to combine matrix factorization and topic modeling for aspect mining (or called aspect rating prediction). However, this idea faces several challenges on how to address suitable sharing factors, scale mismatch, and dependency relation of rating and review information. In this paper, we propose a novel model to effectively integrate Matrix factorization and Topic modeling for Aspect rating prediction (MaToAsp). To overcome the above challenges and ensure the performance, MaToAsp employs items as the sharing factors to combine matrix factorization and topic modeling, and introduces an interpretive preference probability to eliminate scale mismatch. In the hybrid model, we establish a dependency relation from ratings to sentiment terms in phrases. The experiments on two real datasets including Chinese Dianping and English Tripadvisor prove that MaToAsp not only obtains reasonable aspect identification but also achieves the best aspect rating prediction performance, compared to recent representative baselines.  相似文献   

15.
This paper presents an easy-to-use, power-free, and modular pump for portable microfluidic applications. The pump module is a degassed particle desorption polydimethylsiloxane (PDMS) slab with an integrated mesh-shaped chamber, which can be attached on the outlet port of microfluidic device to absorb the air in the microfluidic system and then to create a negative pressure for driving fluid. Different from the existing monolithic degassed PDMS pumps that are generally restricted to limited pumping capacity and are only compatible with PDMS-based microfluidic devices, this pump can offer various possible configures of pumping power by varying the geometries of the pump or by combining different pump modules and can also be employed in any material microfluidic devices. The key advantage of this pump is that its operation only requires the user to place the degassed PDMS slab on the outlet ports of microfluidic devices. To help design pumps with a suitable pumping performance, the effect of pump module geometry on its pumping capacity is also investigated. The results indicate that the performance of the degassed PDMS pump is strongly dependent on the surface area of the pump chamber, the exposure area and the volume of the PDMS pump slab. In addition, the initial volume of air in the closed microfluidic system and the cross-linking degree of PDMS also affect the performance of the degassed PDMS pump. Finally, we demonstrated the utility of this modular pumping method by applying it to a glass-based microfluidic device and a PDMS-based protein crystallization microfluidic device.  相似文献   

16.
Li G  Luo Y  Chen Q  Liao L  Zhao J 《Biomicrofluidics》2012,6(1):14118-1411816
This paper presents an easy-to-use, power-free, and modular pump for portable microfluidic applications. The pump module is a degassed particle desorption polydimethylsiloxane (PDMS) slab with an integrated mesh-shaped chamber, which can be attached on the outlet port of microfluidic device to absorb the air in the microfluidic system and then to create a negative pressure for driving fluid. Different from the existing monolithic degassed PDMS pumps that are generally restricted to limited pumping capacity and are only compatible with PDMS-based microfluidic devices, this pump can offer various possible configures of pumping power by varying the geometries of the pump or by combining different pump modules and can also be employed in any material microfluidic devices. The key advantage of this pump is that its operation only requires the user to place the degassed PDMS slab on the outlet ports of microfluidic devices. To help design pumps with a suitable pumping performance, the effect of pump module geometry on its pumping capacity is also investigated. The results indicate that the performance of the degassed PDMS pump is strongly dependent on the surface area of the pump chamber, the exposure area and the volume of the PDMS pump slab. In addition, the initial volume of air in the closed microfluidic system and the cross-linking degree of PDMS also affect the performance of the degassed PDMS pump. Finally, we demonstrated the utility of this modular pumping method by applying it to a glass-based microfluidic device and a PDMS-based protein crystallization microfluidic device.  相似文献   

17.
We present design, characterization, and testing of an inexpensive, sheath-flow based microfluidic device for three-dimensional (3D) hydrodynamic focusing of cells in imaging flow cytometry. In contrast to other 3D sheathing devices, our device hydrodynamically focuses the cells in a single-file near the bottom wall of the microchannel that allows imaging cells with high magnification and low working distance objectives, without the need for small device dimensions. The relatively large dimensions of the microchannels enable easy fabrication using less-precise fabrication techniques, and the simplicity of the device design avoids the need for tedious alignment of various layers. We have characterized the performance of the device with 3D numerical simulations and validated these simulations with experiments of hydrodynamic focusing of a fluorescently dyed sample fluid. The simulations show that the width and the height of the 3D focused sample stream can be controlled independently by varying the heights of main and side channels of the device, and the flow rates of sample and sheath fluids. Based on simulations, we also provide useful guidelines for choosing the device dimensions and flow rates for focusing cells of a particular size. Thereafter, we demonstrate the applicability of our device for imaging a large number of RBCs using brightfield microscopy. We also discuss the choice of the region of interest and camera frame rate so as to image each cell individually in our device. The design of our microfluidic device makes it equally applicable for imaging cells of different sizes using various other imaging techniques such as phase-contrast and fluorescence microscopy.  相似文献   

18.
We have used Brownian dynamics-finite element method (BD-FEM) to guide the optimization of a microfluidic device designed to stretch DNA for gene mapping. The original design was proposed in our previous study [C. C. Hsieh and T. H. Lin, Biomicrofluidics 5(4), 044106 (2011)] for demonstrating a new pre-conditioning strategy to facilitate DNA stretching through a microcontraction using electrophoresis. In this study, we examine the efficiency of the original device for stretching DNA with different sizes ranging from 48.5 kbp (λ-DNA) to 166 kbp (T4-DNA). The efficiency of the device is found to deteriorate with increasing DNA molecular weight. The cause of the efficiency loss is determined by BD-FEM, and a modified design is proposed by drawing an analogy between an electric field and a potential flow. The modified device does not only regain the efficiency for stretching large DNA but also outperforms the original device for stretching small DNA.  相似文献   

19.
This paper describes the design and implementation of digital controllers for a flywheel energy storage device that incorporates a radial flux hybrid permanent magnetic bearing. Although the uncontrolled device is asymptotically stable, active control is required to: (i) ensure that a finite radial air gap is maintained at all times, and (ii) attenuate the oscillations of the flywheel which reduce the efficiency of the motor generator. The paper presents the design of gain scheduled discrete time linear quadratic regulator (LQR) and linear quadratic Gaussian (LQG) controllers for this rotordynamic system. Real time experiments are conducted to investigate the performance of the controllers. The result indicates that the LQR controller with approximate system velocities is easier to implement than the LQG controller, and also provides superior performance.  相似文献   

20.
We describe a technology based on lamination that allows for the production of highly integrated 3D devices suitable for performing a wide variety of microfluidic assays. This approach uses a suite of microfluidic coupons (“microfloupons”) that are intended to be stacked as needed to produce an assay of interest. Microfloupons may be manufactured in paper, plastic, gels, or other materials, in advance, by different manufacturers, then assembled by the assay designer as needed. To demonstrate this approach, we designed, assembled, and characterized a microfloupon device that performs sodium-dodecyl-sulfate polyacrylamide gel electrophoresis on a small sample of protein. This device allowed for the manipulation and transport of small amounts of protein sample, tight injection into a thin polyacrylamide gel, electrophoretic separation of the proteins into bands, and subsequent removal of the gel from the device for imaging and further analysis. The microfloupons are rugged enough to handle and can be easily aligned and laminated, allowing for a variety of different assays to be designed and configured by selecting appropriate microfloupons. This approach provides a convenient way to perform assays that have multiple steps, relieving the need to design highly sophisticated devices that incorporate all functions in a single unit, while still achieving the benefits of small sample size, automation, and high speed operation.  相似文献   

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