共查询到19条相似文献，搜索用时 109 毫秒
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针对合成类固醇类药物在体育运动中被大量运用的现象，本文从类固醇激素的生理学、临床应用及可能产生的毒副作用三方面阐述了其在人体中的作用。并建议在体育界对滥用合成类固醇事件一定要严肃处理。 相似文献
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合成类固醇制剂的使用及其对人体机能能力的影响 总被引：2，自引：0，他引：2
郑陆 《山东体育学院学报》1997,(1)
合成类固醇是一类拟雄性激素的人工合成药物。由于其对人体机能能力具有特殊的影响作用，一直是体育界最普遍使用的兴奋剂之一。本文对近年来运动员使用合成类固醇以及其对人体器官系统机能能力影响的有关研究进展加以综述讨论，指出合成类固醇对人体具有正反两方面的影响作用，应予以正确对待 相似文献
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合成类固醇作为兴奋剂，在体育界被广泛使用，各国都有服用兴奋剂被查住的先例。合成类固醇又称蛋白同化制剂，是合成代谢类药物，包括合成代谢雄性激素类类固醇和β2激动剂。它们的结构与活性类似于人体雄性激素睾酮的化学合成衍生物，所有的合成雄性激素类类固醇都有与睾酮相似的化学结构。 相似文献
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程宇镳 《体育科技文献通报》2005,13(9)
兴奋剂对于体育界甚至普通人群,都不是一个陌生的名词。但说起内源性兴奋剂和外源性兴奋剂,大家可能就有些模糊了。国际反兴奋剂组织把“内源性”定义为指体内自然生成的,“外源性”定义为人体不能自然生成的。也就是说,合成类固醇属于人类自身可以分泌的叫内源性的,反之,就叫外源性的。内源性合成类固醇比外源性合成类固醇更难检测。在早期使用合成类固醇时,外源性物质使用较多。外源性合成类固醇是一个庞大的家族,据不完全统计,该类物质有44种之多,这还不包括其一些结构类似的化合物。上世纪70年代东欧国家广泛使用的兴奋剂主要就是这类物… 相似文献
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有关药物专家在对这种名为tetrahydrogestrinone(THG)的类固醇的化学成分和作用进行检测分析后,做出了如下公告:1、THG是一种特别研制的合成类固醇,由于化学家已对其做了手脚,使得常规药物检测检查不出来。不久前,一位教练将一支留存有THG的注射器寄给了美国反兴奋剂局(USADA),这才帮助USADA研究出了检测这种药物的方法。2、合成类固醇具有刺激肌肉和骨细胞产生新的蛋白质的作用。它可以增强肌肉力量、促进肌纤维的生长,可成倍增强雄性激素睾酮的作用,因此能使运动员进行强度更大和时间更长的训练。合成类固醇还可使运动员更具攻击… 相似文献
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滥用合成类固醇对运动员肌体的影响和危害 总被引：1，自引：0，他引：1
近几年内,许多世界一流运动员的尿样中被发现有合成类固醇类药物或者其代谢产物,非法出售该类药物的商人从中获得了数百万美元的高额利润。本文将从生理学和医学的角度阐述合成类固醇对人体机能影响及服用后易产生的副作用等人们普遍关心的问题。 相似文献
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田径作为体能主导类项群,生理机能、力量、耐力、速度等运动素质起决定性作用,对大运动负荷后快速恢复有极高的要求。这也是田径运动员服用合成类固醇兴奋剂多的一个原因。甚至有人声称:合成类固醇是田径冠军的早点。而体内原有的高雄激素水平无疑使田径运动员占绝对的竞技优势。 相似文献
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袁飚 《天津体育学院学报》2007,22(5):422-425
目的:针对设计类固醇兴奋剂,分析并探讨其设计特点和发展趋势。方法:文献资料法和理论分析法。结论:设计类固醇兴奋剂是一些没有纳入世界反兴奋剂条例禁用物质清单的类固醇药物,或者是利用兴奋剂检测方法存在的不足为逃脱药检而专门设计的类固醇药物,其未来的主要趋势是制造现今例行的运动兴奋剂控制尿样筛选、检测中容易分解的类固醇兴奋剂;另一个重要的趋势是从现有商品流通渠道和世界反兴奋剂条例禁用物质清单之外寻找或直接开发合成代谢活性高的合成类固醇药物。 相似文献
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从五十年代中期开始,不同类型的蛋白同化激素(或称合成类固醇)如大力补、诺龙等问世,运动员使用和滥用蛋白同化激素类药物逐步成为一个严重的问题。到1960年已经是所有项目都有人使用合成类同醇,以增大肌肉和增强力量。为此,1968年蛋白同化激素被列入国际奥委会禁用的药物之列。一、蛋白同化激素的分类及其在运动员中的滥用情况第二次大战期间德军部队使用蛋白同化激素以增加其攻击性,是使用蛋白同化激素的最早报导。用于运动员则在五十年代初期。早在1954年苏联就有使用合成类固醇的报导。正常男子,特别是力量和体能决定成败关键的运动项目,使用合成类固醇的运动员逐年增加。最初仅限于举重和投掷运动 相似文献
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Marije N. Boks Anton T. Tiebosch Laurens A. van der Waaij 《Journal of sports sciences》2017,35(22):2262-2264
The use of anabolic steroids is prevalent in recreational athletes. This case report describes a young amateur bodybuilder who was referred to our outpatient clinic with jaundice and loss of appetite due to cholestatic hepatitis. Additional tests including a liver biopsy made it likely that the hepatitis was caused by the injectable anabolic steroid trenbolone enanthate. Cholestatic hepatitis may not be limited to the use of oral anabolic–androgenic steroids, as is widely assumed. Therefore, and because of other side effects, the recreational use of all forms of anabolic steroids should be discouraged. 相似文献
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《Sport in History》2013,33(3):434-451
The use of drugs to enhance performance has been a feature of athletic competition since ancient times. This review discusses the use of anabolic steroids and stimulants by athletes to improve performance during the later half of the nineteenth century and during most of the twentieth century. Included are discussions of the development and medical background of testosterone and anabolic steroids, how the use of steroids progressed from medical use to use in sport and, with the rapid expansion of testosterone and steroid use in sport during the 1960s and 1970s, the emergence of adverse health effects that lead to the initial banning of steroids in sports and the development of drug testing programmes. Links between stimulant use, war and sport during the 1930s and 1940s, the impact of stimulant use on post-war sport, and the prevalence of stimulant use in North American society and sport prior to 1970, including the deaths of several elite cyclists, are discussed in the second part of this review. 相似文献
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This essay demonstrates that certain fears in North America and Western Europe over steroid and other banned substance use in sport can be tied to three post-WWII events: reports that the Nazis had abused steroids to increase troop aggressiveness during WWII; claims during the cold war that Communist countries' athletes were utilizing steroids for purposes of totalitarian regime building similar to the manner in which the Nazis had allegedly used them; and allegations that east bloc female athletes were being used to further the cause of Communist regimes by being forced to accept the androgenizing effects of anabolic steroids and other hormone treatments. It is only with a full understanding of the repressed anxieties engendered by these events that the status of current banned substance policies can be fully and accurately evaluated. 相似文献
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Alexander A. Mikheev 《中国体育科技》2009,45(1)
The article presents the most important results of metabolic (hormonal) study of dosed vibration training (DVT).The author presents vibrating training as an alternative to anabolic steroids on the basis of a comparison of the effectiveness of two types of stimulants - forbidden (doping) and non-medicinal non-invasive, relating to permitted physical means.The study shows that the level of androgens (testosterone),corticosteroids (cortisol), thyroid hormones (thyroxine,triiodothyronine),hormones of adenohypophysis (prolactin) increased under the effect of dosed vibration training.At the same time the level of hormones have no changes under traditional strength training with the use of a synthetic anabolic steroid (retabolil).For the duration of a limited period of time (1 microcycles) dosed vibrotraining causes a more powerful secretion of testosterone than the traditional strength training with the use of anabolic steroids. In this case,the overall time spent on the performance of the DVT training program comprises not more than 15% of the time spent on the traditional training exercises. 相似文献
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Thevis M Sauer M Geyer H Sigmund G Mareck U Schänzer W 《Journal of sports sciences》2008,26(10):1059-1065
Drug abuse by adolescents has been investigated in various surveys that reported correlations between age, gender, and activity. However, none of these studies included chemical analyses to help substantiate the statements of participants. In the present study, the urine specimens of 964 students (439 females, 525 males; mean age 22.1 years, s = 1.7), who applied to study sports sciences at university, were assessed for anabolic steroids, stimulants, and selected drugs prohibited in sports. In total, 11.2% of the urine specimens provided contained drugs covered by doping controls. The most frequently detected compound was the major metabolite of tetrahydrocannabinol (9.8%) followed by various stimulants related to amphetamine and cocaine (1.0%). Indications of anabolic steroid use were found in 0.4% of urine samples but originated from contraceptives containing norethisterone. The present study provided unambiguous data on the status quo of drug (ab)use by adolescents hoping for a career related to elite sport or sports sciences. No use of anabolic steroids was detected. However, evidence for stimulants and tetrahydrocannabinol administration was obtained, although not reported by any participant, which highlights the issue of under-reporting in surveys based solely on questionnaires. 相似文献
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Mario Thevis Michael Sauer Hans Geyer Gerd Sigmund Ute Mareck Wilhelm Schänzer 《Journal of sports sciences》2013,31(10):1059-1065
Abstract Drug abuse by adolescents has been investigated in various surveys that reported correlations between age, gender, and activity. However, none of these studies included chemical analyses to help substantiate the statements of participants. In the present study, the urine specimens of 964 students (439 females, 525 males; mean age 22.1 years, s = 1.7), who applied to study sports sciences at university, were assessed for anabolic steroids, stimulants, and selected drugs prohibited in sports. In total, 11.2% of the urine specimens provided contained drugs covered by doping controls. The most frequently detected compound was the major metabolite of tetrahydrocannabinol (9.8%) followed by various stimulants related to amphetamine and cocaine (1.0%). Indications of anabolic steroid use were found in 0.4% of urine samples but originated from contraceptives containing norethisterone. The present study provided unambiguous data on the status quo of drug (ab)use by adolescents hoping for a career related to elite sport or sports sciences. No use of anabolic steroids was detected. However, evidence for stimulants and tetrahydrocannabinol administration was obtained, although not reported by any participant, which highlights the issue of under-reporting in surveys based solely on questionnaires. 相似文献
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