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11.
Peganum harmala L. (Zygophyllaceae) is a traditional medicine used for the treatment of variety of human ailments, including antidepression, hallucination, antileishmaniasis etc. We report for first time the hypoglycemic activity of the ethanolic extract of this plant at two dose levels of 150 and 250mg/kg bw in sucrose challenged normal as well as in rats with streptozotocin induced diabetes. The oral administration of ethanolic extract causes maximum fall of blood glucose level to 22.9% (p<0.05) and 29.4% (p<0.01) respectively with the two doses in normal and 30.3% (p<0.01) and 48.4% (p<0.001) in diabetic rats. The standard drug metformin treated group showed 28.0% (p<0.01) and 45.5% (p<0.001) respectively in normal and diabetic rats. The above results show that the ethanolic extract of P. harmala is as effective as metformin in reducing the blood glucose levels of normoglycemic and streptozotocin-induced diabetic rats.  相似文献   
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The present article investigates the Chinese peoples’ interdependent and independent self‐construals, including how these self‐construals are influenced by socio‐demographic factors such as age, gender, and rural‐urban residence. A modified version of Singelis’ (1994) self construal scale was administered to 237 Chinese respondents’ in an urban and a rural area of Shandong Province, China, and qualitative data (focus group and in‐depth interviews) were collected to enrich the quantitative findings. Our results suggest that the Chinese self‐construal varies across age, gender, and urban‐rural residence, and is also influenced by the changing political, economic, and socio‐cultural context in China. The theoretical and practical implications for the field of intercultural communication are outlined in the discussion section.  相似文献   
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TV evening news coverage of the 2008 presidential election by broadcast, cable, and public networks was predominately male and Caucasian in terms of reporters and sources. However, according to our content analysis of 888 campaign stories, viewers saw the least amount of source diversity if they watched the evening news on broadcast networks ABC, CBS, and NBC. Cable networks FOX and CNN, and the PBS evening news had more female and non-White sources. This pattern also holds true for reporter use of nonpartisan sources. Findings on the 2008 election for the traditional broadcast networks are not consistent with those for the 2000 and 2004 elections, when female reporters at these networks had more female and nonpartisan sources in their election coverage than did their male colleagues. Reporters at PBS provided the greatest overall source diversity, regardless of their race or gender, compared to what was observed on broadcast and cable networks. Differences in the way reporters used women and non-White sources to cover the 2008 presidential race may be attributable to organizational factors.  相似文献   
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We examine the incident known as “Climategate” in which emails and other documents relating to climate scientists and their work were illegitimately accessed and posted to the Internet. The contents of the files prompted questions about the credibility of climate science and the legitimacy of some of the climate scientists’ practices. Multiple investigations unfolded to repair the boundary that had been breached. While exonerating the scientists of wrongdoing and endorsing the legitimacy of the consensus opinion, the investigating committees suggested revisions to some scientific practices. Despite this boundary repair work, the credibility and legitimacy of the scientific enterprise were not fully restored in the eyes of several stakeholders. We explore why this is the case, identify boundary bridging approaches to address these issues, and highlight policy implications.  相似文献   
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A total of 172 first degree relatives (FDRs) and 178 controls were included in this study. All the cases and controls were subjected to various anthropometric measurements, fasting and postprandial glucose estimation, fasting insulin measurement and fasting lipid profile. Results revealed the prevalence of Impaired Fasting Glucose (IFG) (cases 37% Vs controls 11.6%), Impaired Glucose Tolerance (IGT) (cases 34.3% Vs controls 11.2%) and diabetes (cases 11.05% controls 3.37%) was significantly higher in first degree relatives. Insulin resistance was measured using various methods, which included fasting plasma insulin (FPI), Homeostasis Model Assessment for Insulin Resistance (HOMAIR), insulin sensitivity index (ISI) (Mffm/l). Prevalence of insulin resistance (Insulin Resistance) as observed comparing FPI and HOMAIR in cases and controls was 43.6% and 11.24% (P=0.005) and 37.8% and 12.47% (P=0.000) respectively. Prevalence of IR (Insulin Resistance) observed in cases having Normal Glucose Tolerance (NGT), Impaired Fasting Glucose (IFG), Impaired Glucose Tolerance (IGT) and diabetes mellitus measuring FPI Vs HOMAIR was 37.5% vs 30.2%, 45% vs 40%, 38.98% vs 37.28% and 36.84% vs 31.57% as accordingly. However, ISI (Mffm/l) was not found to be a promising index for IR due to its poor specificity. Though HOMA is taken as gold standard for measurement of IR globally, our study observed fasting plasma insulin representing high sensitivity (89.7%) and specificity (93.3%) as compared to HOMA. Thus FPI had emerged in this work as a simple and reliable test for diagnosing insulin resistance across the population susceptible to develop diabetes including FDRs.  相似文献   
16.
The root of Glycyrrhiza glabra is a traditional medicine used mainly for the treatment of peptic ulcer, hepatitis C, pulmonary and skin diseases, although clinical and experimental studies suggest that it has several other useful pharmacological properties such as antiinflammatory, antiviral, antimicrobial, antioxidative, anticancer activities, immunomodulatory, hepatoprotective and cardioprotective effects. Glycyrrhizinic acid, a major component of licorice, has antiulcer effect by raising the local concentration of prostaglandins that promote mucous secretion and cell proliferation in the stomach. Glycyrrhizin shows hepatoprotective effect by preventing changes in cell membrane permeability, inhibiting phospholipase A2 (PLA2) and increasing survival rate of hepatocytes. Glabridin has effect in melanogenesis and inflammation by inhibiting the tyrosinase activity of melanocytes. α-glycyhrritinic acid exhibits anti-inflammatory activity by inhibiting glucocorticoid metabolism. In present study ethanolic (95%) extract of root of Glycyrrhiza glabra and its fractions were investigated for its antidyslipidaemic activity on HFD induced dyslipidaemic hamsters. Ethanolic extract and its ethyl acetate soluble, water soluble and hexane soluble fractions decreased serum level of total cholesterol by 25.9, 38.0, 39.0 and 26.3%, respectively. On the other hand ethanolic extract, ethyl acetate soluble, water soluble and hexane soluble fraction increased the serum HDL-cholesterol level by 14.8, 34.3, 27.3 and 17.2%, respectively. Ethanolic extract, ethyl acetate fraction, aqueous fraction and hexane fraction decreased triglyceride level by 31.3, 37.2, 41.2 and 28.9%, respectively. The reduction in LDL-cholesterol level by ethanolic extract, ethyl acetate soluble fraction and water soluble fraction were 43.9, 31.0, 33.4 and 24.6%, respectively.  相似文献   
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This study examined how race and gender of reporters and community diversity influenced use of women and minority sources in local television coverage of the 2002 governor's race in Michigan. Content analysis of campaign stories broadcasted by four local television stations revealed that women reporters were more likely than their male colleagues to use women and nonpartisan sources such as experts and ordinary citizens. But minority journalists were only slightly more likely to use minority sources and were less likely than nonminorities to use nonpartisan sources.  相似文献   
20.

This concluding part of a study on Galilean relativity focuses on students’ notions with regard to the inertial and non‐inertial character of frames of reference. (See Panse et al. 1994, Ramadas et al. 1996). The results show that students: adopt kinematic criteria for deciding the inertial or non‐inertial character of frames; consider this character to be a ‘relative’ property of two frames rather than an intrinsic property of a given frame; and equate pseudo‐forces to ‘imaginary’ forces. Centrifugal force is associated with rotating objects rather than with rotating frames; the latter are localized by the finite extension of their associated objects. Anthropomorphic criteria are invoked to judge the existence of centrifugal force, which is regarded as a reaction (in the sense of Newton's third law) to the centripetal force on a rotating object.  相似文献   
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