Robust fluidic connections to freestanding microfluidic hydrogels     

Shannon L. Faley  Bradly B. Baer  Taylor S. H. Larsen  Leon M. Bellan 《Biomicrofluidics》2015,9(3)

Biomimetic scaffolds approaching physiological scale, whose size and large cellular load far exceed the limits of diffusion, require incorporation of a fluidic means to achieve adequate nutrient/metabolite exchange. This need has driven the extension of microfluidic technologies into the area of biomaterials. While construction of perfusable scaffolds is essentially a problem of microfluidic device fabrication, functional implementation of free-standing, thick-tissue constructs depends upon successful integration of external pumping mechanisms through optimized connective assemblies. However, a critical analysis to identify optimal materials/assembly components for hydrogel substrates has received little focus to date. This investigation addresses this issue directly by evaluating the efficacy of a range of adhesive and mechanical fluidic connection methods to gelatin hydrogel constructs based upon both mechanical property analysis and cell compatibility. Results identify a novel bioadhesive, comprised of two enzymatically modified gelatin compounds, for connecting tubing to hydrogel constructs that is both structurally robust and non-cytotoxic. Furthermore, outcomes from this study provide clear evidence that fluidic interconnect success varies with substrate composition (specifically hydrogel versus polydimethylsiloxane), highlighting not only the importance of selecting the appropriately tailored components for fluidic hydrogel systems but also that of encouraging ongoing, targeted exploration of this issue. The optimization of such interconnect systems will ultimately promote exciting scientific and therapeutic developments provided by microfluidic, cell-laden scaffolds.  相似文献   

‘Pink Tea and Sissy Boys’: Digitized Fragments of Male Homosexuality,Non-Heteronormativity and Homophobia in the Australian Sporting Press, 1845–1954     

Gary Osmond 《国际体育史杂志》2015,32(13):1578-1592

Researching the gay sporting past is difficult because of the dearth of written evidence. This article employs digital history techniques, specifically the distant and close reading of newspapers, in an attempt to locate references to male homosexuality in the Australian sporting press. The focus is not on finding references to homosexual athletes, but rather on locating attitudes, innuendo and inferences concerning homosexuality, non-heteronormative masculinity and homophobia. The sophisticated search engine provided by Trove – the digitization programme of the National Library of Australia – allows for specific word searches across 170 million articles from 800 newspapers from 1803 to 1954, including a handful of sport-themed publications. This project uses a distant-reading approach to find instances of contemporaneous homosexual-related terms – colloquialism, euphemism, legal parlance and slurs – in four popular sport newspapers and to focus on two words: effeminate and sissy. Given the commonality and multiple meanings of these words, a close reading is necessary to filter these findings in order to facilitate a reading of the ‘snippets and shadows’ of homosexuality that remain.  相似文献   

Interactive Kiosk at the Texas Tech University Libraries     

Ryan Litsey  Susan Hidalgo  Kaley Daniel  Julie Barnett  Amy Kim  Shannon Jones 《Journal Of Access Services》2015,12(1-2):31-41

The academic library, given its often privileged position on campus, is the information source that can include directional as well as general campus facts among the myriad of print and e-resources for reference. Also, an academic library's audiences can be quite varied and include prospective students or parents seeking more general knowledge of the building and the campus. Many times this need for information drives patrons to the library service desks. Sometimes, especially during the high-demand seasons of new student orientation and beginning of the fall semesters, the desk is so busy that many patrons will leave because they don't have the time to wait. To address this immediate need for information, Texas Tech University Libraries developed an interactive kiosk to provide general information for frequently asked questions in a more efficient, creative, and interactive way. The kiosk provides a fun method of satisfying a patron's information needs without the requirement of a staff member or the need to wait in line for help. The kiosk is available as long as the Library is open and provides a variety of useful answers to general questions, as well as facts about the Library.  相似文献   

Into the gray: a modified approach to citation analysis to better understand research impact     

Shannon L. Sibbald  Jennifer C. D. MacGregor  Marisa Surmacz  C. Nadine Wathen 《Journal of the Medical Library Association》2015,103(1):49-54

  相似文献   

It Costs a Lot to Look This Cheap: Preference for Low-Quality Graphic Design     

Shannon Zenner 《Visual Communication Quarterly》2019,26(1):22-31

Some 1,000 surveys were conducted on Amazon's MTurk, asking respondents to rate a high- and low-quality visual design, in this case a billboard ad. While most respondents preferred the high-quality ad, over a third opted for the low-quality design. Respondents who showed a preference for the low-quality design liked it for its “static” qualities, in that it was common, typical, average, and standard. Those who preferred the high-quality design liked it for its “dynamic” qualities, such that it was innovative, fascinating, novel, creative, and rich in elements. Older participants show a significant preference for the low-quality design. Implications of these findings for different types of visual communication are discussed.  相似文献   

Professor Richard Aldrich: an appreciation     

Gary McCulloch 《Journal of educational administration and history》2015,47(4):327-333

  相似文献   

Implementing a Multi-Tiered System of Support (MTSS): Collaboration Between School Psychologists and Administrators to Promote Systems-Level Change     

John W. Eagle  Shannon E. Dowd-Eagle  Andrew Snyder  Elizabeth Gibbons Holtzman 《Journal of educational and psychological consultation》2015,25(2-3):160-177

Current educational reform mandates the implementation of school-based models for early identification and intervention, progress monitoring, and data-based assessment of student progress. This article provides an overview of interdisciplinary collaboration for systems-level consultation within a Multi-Tiered System of Support (MTSS) framework. The roles of school psychologists and school-based administrators are presented in relation to the implementation of MTSS practices within an implementation science model. The training and expertise of each discipline are highlighted related to respective aspects of implementation drivers (i.e., competency, organization, leadership). Functions of principals and school psychologists during team-based, problem-solving MTSS practices are described based on a problem-solving framework consistent with school-based consultation. Future directions for graduate training of school psychologists and principals and directions for consultation research are provided.  相似文献   

Students’ Perspectives on LGBTQ-Inclusive Curriculum     

Shannon D. Snapp  Hilary Burdge  Adela C. Licona  Raymond L. Moody  Stephen T. Russell 《Equity & Excellence in Education》2015,48(2):249-265

Implementing curriculum that is inclusive of lesbian, gay, bisexual, transgender, queer, and questioning (LGBTQ) people has the potential to create an equitable learning environment. In order to learn more about students’ experiences of LGBTQ-inclusive curriculum, 26 high school students with diverse racial/ethnic, sexual, and gender identities were recruited from the Gay Straight Alliance (GSA) Network in California. Students participated in focus groups conducted by telephone by GSA staff, sharing their experiences of LGBTQ-inclusive curriculum in school. Qualitative coding methods, including grounded theory, were used to identify themes and interpret students’ responses. Data revealed that LGBTQ-inclusive curriculum was most often taught in social sciences and humanities courses as stand-alone lessons. LGBTQ-inclusive curriculum rarely met standards of social justice education, though opportunities for critical conversations about systemic oppression regularly emerged. For instance, teachers often failed to intervene in LGBTQ bullying and missed teachable moments conducive to inclusive curriculum. Some students learned positive LGBTQ lessons and highlighted the ways such curriculum reflected their identities and created a supportive school climate. Implications for equitable education are discussed.  相似文献   

Team learning in IT implementation projects: Antecedents and consequences     

Ali E. Akgün  Gary S. Lynn  Halit Keskin  Derya Dogan 《International Journal of Information Management》2014

This study investigates the antecedents and consequences of team learning, which is composed of information acquisition, dissemination, and implementation, in information technology (IT) implementation projects. By investigating 129 IT implementation project teams, we found that (1) information acquisition and information dissemination have a positive impact on project outcomes, such as speed-to-users, lower implementation cost, and operational effectiveness, and (2) team behavior and enabler variables, such as teamwork, team communication, interpersonal trust between team members, team commitment, and senior manager support, positively influence team learning. We also found that team anxiety moderates the relationship between team learning and project outcomes.  相似文献   

Student Teaching by Any Other Name: The Impact of Metaphor     

Gary Dohrer 《Teaching Education》2013,24(1):125-132

  相似文献