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Bhaskar Upadhyay Geoffrey Maruyama Nancy Albrecht 《International Journal of Science Education》2013,35(18):2528-2547
ABSTRACTIn this interpretive case study, we draw from sociocultural theory of learning and culturally relevant pedagogy to understand how urban students from nondominant groups leverage their sociocultural experiences. These experiences allow them to gain an empowering voice in influencing science content and activities and to work towards self-determining the sciences that are personally meaningful. Furthermore, tying sociocultural experiences with science learning helps generate sociopolitical awareness among students. We collected interview and observation data in an urban elementary classroom over one academic year to understand the value of urban students’ sociocultural experiences in learning science and choosing science activities. 相似文献
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Bhaskar Upadhyay 《Cultural Studies of Science Education》2009,4(3):601-610
As we contemplate on teacher identity research, there is a need to place a teacher’s narratives or story-lines at the center of that work. In this forum, in response to the insightful commentary from Stephen Ritchie and Maria Iñez Mafra Goulart and Eduardo Soares, I place a greater emphasis on understanding Daisy’s narratives from an existing social identity framework. Narratives tell us intricate and complex actions that a teacher has taken both personally and professionally. Additionally, narratives help us see implicit nature of identity explicitly. Therefore, a greater focus has to be placed on interactions and utterances of a teacher to make sense of who they are and what they do as expressed by their own words (identity and action). Finally, I join with Ritchie and Goulart and Soares to advocate that identity research needs to include participants as co-researchers and co-authors as identities are very personal and complex to be fully understood by the outsiders (researchers). 相似文献
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I. Rahman A. Upadhyay V. Tule N. Nath 《Indian journal of clinical biochemistry : IJCB》1993,8(1):29-32
We studied the membrane potentials of normal, essential hypertensive, diabetes mellitus and rheumatoid arthritic polymorphonuclear leukocytes (PMNL). It was found that diabetic PMNL were grossly hyperpolarized as compared to normal. On the other hand hypertensive and arthritic PMNL elicited a significant depolarization. The PMNL obtained from treated hypertensive patients showed considerable recovery where as partial recovery was evidenced in membrane potentials in diabetic and arthritic PMNL. The implications are discussed. 相似文献
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Jigna Joshi Apexa Raval Urja Desai Vinal Upadhyay Mansi Bhavsar Kanisha Shah Rakesh Rawal Harsha Panchal Franky Shah 《Indian journal of clinical biochemistry : IJCB》2021,36(1):51
In the era of the targeted therapy identification of EGFR mutation detection in lung cancer is extremely helpful to predict the treatment efficacy of EGFR tyrosine kinase inhibitors (TKIs). Unfortunately, the inadequacy and quality of the biopsy samples are the major obstacles in molecular testing of EGFR mutation in lung cancer. To address this issue, the present study intended to use liquid biopsy as the non-invasive method for EGFR mutation detection. A total of 31 patients with an advanced stage of lung cancer were enrolled in the study from which cell-free DNA (cfDNA) and FFPE tissue DNA was extracted. Extracted DNA samples were analyzed for further EGFR exon specific mutation analysis by ARMS-PCR. Data were analyzed statistically using SPSS software. In cfDNA samples, the prevalence of wild type EGFR was 48% while the prevalence of TKI resistant and TKI sensitive mutations were 3%. Conversely, in tissue DNA samples, the prevalence of wild type, TKI sensitive and TKI resistant mutations were 48%, 19%, and 3%, respectively. The overall concordance of EGFR mutation between cfDNA and tissue DNA was 83%. McNemar’s test revealed that there was no significant difference between EGFR expression of cfDNA and tissue DNA samples. Additionally, the significant-high incidence of TKI resistant mutations was observed in tobacco habituates, indicating the role of carcinogens present in the tobacco in developing resistant mutations. In conclusion, our data suggest that evaluation of EGFR mutation from cfDNA samples is practicable as a non-invasive tool in patients with advanced-stage of lung cancer. 相似文献
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In this paper a population based evolutionary optimization methodology called Opposition based Harmony Search Algorithm (OHS) is applied for the optimization of system coefficients of adaptive infinite impulse response (IIR) system identification problem. The original Harmony Search (HS) algorithm is chosen as the parent one and opposition based approach is applied to it with an intention to exhibit accelerated near global convergence profile. During the initialization, for choosing the randomly generated population/solution opposite solutions are also considered and the fitter one is selected as apriori guess for having faster convergence profile. Each solution in Harmony Memory (HM) is generated on the basis of memory consideration rule, a pitch adjustment rule and a re-initialization process which gives the optimum result corresponding to the least error fitness in multidimensional search space. Incorporation of different control parameters in basic HS algorithm results in balancing of exploration and exploitation of search space. The proposed OHS based system identification approach has alleviated from inherent drawbacks of premature convergence and stagnation, unlike Genetic Algorithm (GA), Particle Swarm Optimization (PSO) and Differential Evolution (DE). The simulation results obtained for some well known benchmark examples justify the efficacy of the proposed OHS based system identification approach over GA, PSO and DE in terms of convergence speed, identifying the system plant coefficients and mean square error (MSE) fitness values produced for both same order and reduced order models of adaptive IIR filters. 相似文献
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This paper examines the perceptions of three Somali mothers on science, science topics taught in urban US schools and the challenges that they encountered in dealing with science and their own social and cultural practices. The article focuses on Somali mothers, who were highly interested in articulating how science and science professions could be a path to both the personal and community successes and how science could positively affect Somali girls in the areas of women’s health. As an exploratory case study research, we used grounded theory approach to understand Somali mothers’ perceptions of science. We interviewed the mothers over a year and analyzed data as an iterative and systematic process. The findings of the study show that the Somali mothers perceived science from everyday usefulness points of view rather than science knowledge alone, thus home-science connections were critical to them as Somali mothers. They perceived science as an empowering tool for girls so they could make important decisions about women’s reproductive health issues. A broader implication of this study could be for urban science teachers and educators to modify their science instructional and curricular decisions so science learning is connected to Somali students’ culture and empowers girls. 相似文献
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Cultural Studies of Science Education - In this conceptual paper, we argue that social justice, morality, and healing must be at the core of an equity agenda for science education. When we view... 相似文献
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Fortney Brian S. Morrison Deb Rodriguez Alberto J. Upadhyay Bhaskar 《Cultural Studies of Science Education》2019,14(2):259-263
Cultural Studies of Science Education - 相似文献