The largest and oldest living organism     

Ramesh Maheshwari 《Resonance》2005,10(4):4-9

A fungus hidden beneath the soil surface in forest, estimated to be 1500–2400 years old, is the largest and oldest living organism.  相似文献   

Conservation of a room: A treatment proposal for Mark Rothko's Harvard Murals     

Jens Stenger  Narayan Khandekar  Ramesh Raskar  Santiago Cuellar  Ankit Mohan  Rudolf Gschwind 《文物保护研究》2016,61(6):348-361

A treatment with projected light for Mark Rothko's Harvard Murals (1962) is proposed. The group of five paintings on canvas has changed color due to the presence of a fugitive red pigment and excessive exposure to natural light in a room with large windows. For the conservation of Rothko's Harvard room, it is brought into context within his other commissions and environments. The original color of the works is determined by the digital restoration of contemporary photographs. With a camera projector system a compensation image is calculated that is projected onto the original canvas resulting in a restored color appearance. This approach of inpainting with light is compared with considerations of cleaning and inpainting in conventional conservation treatments. Overall lighting and architecture including the unusual wall color carefully chosen by Rothko play a key role in the treatment of the Mural cycle as an environment.  相似文献   

Antidyslipidemic and antioxidant activities of different fractions of<Emphasis Type="Italic">Terminalia arjuna</Emphasis> stem bark     

Ramesh Chander  Kavita Singh  A K Khanna  S M Kaul  Anju Puri  Rashmi Saxena  Gitika Bhatia  Farhan Rizvi  A K. Rastogi 《Indian journal of clinical biochemistry : IJCB》2004,19(2):141-148

Terminalia arjuna (T. arjuna) stem bark was successively extracted with petroleum ether (A), solvent ether (B), ethanol (C) and water (D). The lipid lowering activity of these four fractions A, B, C, and D was evaluatedin vivo in two models viz., triton WR-1339 induced hyperlipemia in rats as well as fructose rich high fat diet (HFD) fed diabetic- dyslipidemic hamsters. Hyperlipidemia induced by triton caused marked increase in the plasma levels of total cholesterol (Tc), triglyceride (Tg) and phospholipids (PL) in rats. After treament withT. arjuna fractions A, B, C, and D at the doses of 250 mg/kg per oral (p.o.),only the ethanolic fraction (C) exerted significant lipid lowering effect as assessed by reversal of plasma levels of Tc, Tg and PL in hyperlipidemic rats. In another experiment, feeding with HFD produced marked dyslipidemia as observed by increased levels of plasma Tc, Tg, glucose (Glu), glycerol (Gly) and free fatty acids (FFA) in hamsters. After treatment withT. arjuna fractions at the doses of 250 mg/kg p.o. only two fraction (B and C) could exert significant lowering in the plasma levels of lipids and Glu. in dyslipidemic hamsters.In vitro experimentT. arjuna fractions at tested concentrations (50–500 μg/ml) inhibited the oxidative degradation of lipids in human low density lipoprotein and rat liver microsomes induced by metal ions. These fractions when tested against generation of oxygen free radicals at the concentrations (50–500 μg/ml), counteracted the formation of superoxide anions (O⁻²) and hydrodyl radicals (OH) in non enzymic test systems. The efficacy ofT. arjuna fractions as antidyslipidemic and antioxidant agents was found, fraction C> fraction B> fraction A.  相似文献   

Where Information Society and Community Voice Intersect     

Ramesh Srinivasan 《The Information Society》2006,22(5):355-365

Information and communication technology (ICT) development initiatives have begun to acknowledge the power and importance of cultural and community-focused belief systems. Yet the vast majority of such initiatives tend to preidentify developmental goals that communities hold. Paulo Freire's writings have influenced development initiatives by introducing the possibility of working with communities to orient projects. While these “participatory” initiatives have involved soliciting community feedback relative to a research project whose goals were formulated in the university or development institution, they do not go far enough to harness actual visions held by communities. It is important to conceptualize a model and methodology of engaging communities to develop and articulate their own goals of information access and ultimately, an indigenous approach toward cultural, political, and economic aspects of development. This approach holds promise to sustain communities within a return on the investment and efforts of the researcher or institution. This article closes by describing a current initiative in Southern India that reflects the described methodology.  相似文献   

Optimization theory : by David L. Russell. 405 pages. New York,Benjamin, 1970. Price $7.95 (paper-back, $17.50 (hard cover) (approx. £3·15 and £6·32, respectively).     

Ramesh C. Jain 《Journal of The Franklin Institute》1973,296(3):222-223

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Role of bilirubin, vitamin C and ceruloplasmin as antioxidants in coronary artery disease [CAD]     

V. K. Verma  V. Ramesh  Satyendra Tewari  R. K. Gupta  Nakul Sinha  C. M. Pandey 《Indian journal of clinical biochemistry : IJCB》2005,20(2):68-74

A study has been carried out on 250 CAD patients to see how the serum levels of three antioxidants i.e., Vitamin C, Bilirubin and Ceruloplasmin are related to the CAD risk factors and characteristics in these patients. The number of severe category CAD patients declined by 7–18% with increasing serum levels of the three antioxidants and, triple vessel disease declined by 14–20%. A decline of 39% in Myocardial Infarction (MI) occurred with increasing serum Ceruloplasmin. Serum Ceruloplasmin was significantly lower in the MI group compared to the non MI group CAD patients. There was a steady and a significant decline in the mean values of serum levels of cholesterol, Triglyceride, VLDL cholesterol along with BMI with increasing serum level. The study indicates that with increasing serum levels of the three antioxidants studied, the % MI along with % Triple vessel disease and severity of CAD goes down suggesting that the modifiable risk factors have to be suitably modified in order to maintain a reasonably high level of these antioxidants, as the risk factors are inversely related to the serum antioxidant levels.  相似文献   

Hypoglycemic, lipid lowering and antioxidant activities in root extract of Anthocephalus indicus in alloxan induced diabetic rats     

Vishnu Kumar  A. K. Khanna  M. M. Khan  Ranjana Singh  Sushma Singh  Ramesh Chander  Farzana Mahdi  J. K. Saxena  Shweta Saxena  V. K. Singh  R. K. Singh 《Indian journal of clinical biochemistry : IJCB》2009,24(1):65-69

The present study was carried out to evaluate the hypoglycemic, lipid lowering and antioxidant activities in root extract of Anthocephalus indicus (A indicus) in alloxan inducd diabetic rats. Oral administration of ethanol extract of root (500mg/ kg body weight) for 21 days resulted in significant decrease in the levels of blood glucose, triglycerides, total cholesterol, phospholipid and free fatty acids. Furthermore, the root extract (100–400μg) inhibited the generation of superoxide anions and hydroxyl radicals, in both enzymic and non-enzymic systems, in vitro. The result of the present study demonstrated hypoglycemic, lipid lowering and antioxidant activities in root extract of A indicus, which could help in prevention of diabetic dyslipidemia and related diseases.  相似文献   

An opium alkaloid-papaverine ameliorates ethanol-induced hepatotoxicity: Diminution of oxidative stress     

Ramesh Chandra  Ritu Aneja  Charu Rewal  Rama Konduri  Sujaka K. Dass  Shefali Agarwal 《Indian journal of clinical biochemistry : IJCB》2000,15(2):155-160

In this communication, we show the modulatory potential of papaverine, an opium alkaloid and a well known vasodilator agent on the ethanol-induced hepatic oxidative stress in male Wistar rats. Ethanol treatment (50% v/v) enhanced lipid peroxidation significantly accompanied by a decline in the activities of glutathione peroxidase (G-Px), glutathione reductase (GR) and depletion in levels of hepatic glutathione (GSH). Ethanol administration increased hepatic glutathione-s-transferases (GST). Enhanced lipid peroxidation induced by ethanol was significantly reduced when papverine was coadministered (P<0.05). In addition, the depleted levels of glutathione and inhibited activities of G-Px and GR recovered significantly (P<0.05) levelling off to control values on co-exposure. Papaverine (200 mg/kg bw) effectively antagonised the ethanol-induced lipid peroxidation and impaired glutathione levels and glutathione dependent enzyme systems. Our results suggest that papaverine is an effective chemopreventive agent in the liver and may suppress the ethanol-induced hepatotoxicity.  相似文献   

Predictive value of serum thyroglobulin in treated patients with differentiated thyroid carcinoma     

D. Charles Stephen  M. S. Seshadri  Regi Oommen  Aravindan Nair  S. Swaminathan  A. S. Kanagasabapathy 《Indian journal of clinical biochemistry : IJCB》1999,14(1):26-32

An in-house radioimmuno assay for serum thyroglobulin was developed in our laboratory and compared its relative sensitivity with that of whole body scan in the detection of residual tumour or metastases and evaluated the predictive value of serum thyroglobulin in the clinical course of the disease. Ninety six patients after thyroidectomy were followed up for a maximum period of five years in this study. The sensitivity and specificity of serum thyroglobulin were found to be close to that of whole body scan (85% and 94% respectively). According to this study, a serum thyroglobulin >40 ng/ml can differentiate between patients with metastases and those in remission. Serum thyroglobulin can replace whole body scan during the subsequent follow-up if the patient had concordant whole body scan and serum thyroglobulin during initial assessment.  相似文献   

The riddle of theapparently hollow Himalaya     

Ramesh Chander 《Resonance》1998,3(1):21-26

We recall here an application of Newton’s law of gravitation which suggested prima facie that the Himalaya may be hollow inside  相似文献