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排序方式: 共有402条查询结果,搜索用时 15 毫秒
51.
52.
Lynne Kendall 《Education 3-13》2019,47(2):135-147
This study draws upon data gathered from five parents who have children with Down syndrome (DS), being educated in mainstream settings in England. The parental perspective of practices, both inclusive and otherwise, is explored through a qualitative lens. Findings suggest that early intervention, such as portage, is important. However, access to services varied across authorities. Additionally, some participants highlighted issues around the Education, Health Care Plan and subsequent annual reviews. Overall, this study offers examples of inclusive practice in the areas of supporting language and communication needs, parental partnership and transition between educational phases for children with DS. However, there are inconsistencies across providers and there is a need for more research into these areas in the future. 相似文献
53.
Objective: To explore the relationship between genetic polymorphisms in methylenetetrahydrofolate reductase (MTHFR), methionine synthase reductase (MTRR), the central enzymes in folate metabolism that affects DNA methylation and synthesis, and the risk of Down syndrome in China. Methods: Genomic DNA was isolated from the peripheral lymphocytes of 64 mothers of children with Down syndrome and 70 age matched control subjects. Polymerase chain reaction and restriction fragment length polymorphism were used to examine the polymorphisms of MTHFR 677C→T, MTRR 66A→G and the relationship between these genotypes and the risk of Down syndrome was analyzed. Results: The results show that the MTHFR 677C→T polymorphism is more prevalent among mothers of children with Down syndrome than among control mothers, with an odds ratio of 3.78 (95% confidence interval (CI), 1.78~8.47). In addition, the homozygous MTRR 66A→G polymorphism was independently associated with a 5.2-fold increase in estimated risk (95% CI, 1.90~14.22). The combined presence of both polymorphisms was associated with a greater risk of Down syndrome than the presence of either alone, with an odds ratio of 6.0 (95% CI, 2.058~17.496).The two polymorphisms appear to act without a multiplicative interaction. Conclusion: MTHFR and MTRR gene mutation alleles are related to Down syndrome, and CT, TT and GG gene mutation types increase the risk of Down syndrome. 相似文献
54.
高莉萍 《泰州职业技术学院学报》2004,4(1):63-64
更年期是人生的重要阶段,是生命之秋,也是多病多难之时。更年期综合征的临床常见证型有:肝肾阴虚型,脾肾阳虚型,心脾两虚型,肝郁脾虚型。准确的辨证是治疗本病的关键,治以“绝经后着重在脾”为要点, 相似文献
55.
慢性疲劳综合症的神经内分泌免疫研究进展 总被引:1,自引:0,他引:1
徐建芬 《浙江教育学院学报》2007,(2):59-61,72
慢性疲劳综合症是现代医学新认识的疾病,发病机制复杂.最近研究发现,细胞免疫功能和细胞因子表达的异常、内分泌功能的紊乱以及神经系统功能的异常可能参与该病的病理机制,因此神经内分泌免疫系统的失调是引发慢性疲劳综合症的重要因素. 相似文献
56.
《躺在黑暗中》是斯泰伦的成名作。小说通过主人公悲惨而短暂的人生记录了社会、情感和精神等方面混乱无序的状况。作者使用了多视角叙述、内心独白和并置平行等创作手法深刻地透视了小说人物,特别是悲剧主人公在面临传统道德沦丧、宗教信仰危机时,所经历的内心冲突和痛苦挣扎。 相似文献
57.
生理学中“线粒体DNA(mtDNA)”研究近年来取得重大进展 ,学者们十分关注它的突变与人类疾病的关系。本文综述了mtDNA的结构 ,遗传特点 ,突变类型和几种常见的综合症及临床症状 ,力求展示出研究的新进展 相似文献
58.
从前语言阶段、语音和词汇发展、形态句法习得和语用发展这四个方面对以英语为母语的唐氏儿童语言发展研究的现状和成果作了分析,并在此基础上提出今后的研究趋势以及在我国开展唐氏综合症儿童语言发展研究的意义和紧迫性。 相似文献
59.
Julie A. Millar Janet Thompson Dorothy Schwab Ana Hanlon‐Dearman Deborah Goodman Gal Koren Paul Masotti 《Journal of Research in Special Educational Needs》2017,17(1):3-17
Fetal alcohol spectrum disorder (FASD ) is a prevalent neurodevelopmental disability with significant implications for learning and behaviour. International research suggests that the prevalence of FASD in school‐aged children is 2.3–6.3%. In this paper, we address the questions: (1) what is FASD ; (2) what is the prevalence of FASD in schools; (3) what is the impact of FASD ; and (4) why develop special FASD education strategies and programmes? We summarise the 18‐year history of W innipeg S chool D ivision's development of its FASD P rogramme of services, describe the specialised FASD classrooms and then present the results from a consensus‐generating workshop comprised of 36 FASD education professionals, with over 209 years of collective FASD education programme experience, who were asked to identify and reach consensus on best strategies and lessons learned in FASD education programmes. We then suggest that effectively educating children with FASD is critical to get right if positive educational outcomes are to be realised. 相似文献
60.
目的 :总结严重急性呼吸综合征 (SARS)的胸部X线表现及变化规律。方法 :分析 5 1例经临床确诊的SARS患者一系列胸部X线进行统计分析。结果 :患者均以发热为最早发病症状 ,10 0 %患者在发病后 1周内X线胸片出现局灶性斑片状模糊阴影 ,2周内达到高峰 ,15 .6 %患者为双肺多肺炎性病变 ,5 2 .9%患者为左肺 ,右肺为 31.4 % ,大部分肺野受累 ,病情重 ,98%患者在 4周内肺部阴影逐渐消散。结论 :肺部病变越早 ,范围越广 ,发展越迅速 ,临床症状越重。 相似文献