游泳运动对慢性心理应激大鼠延髓内皮素及其受体的影响   总被引：1，自引：0，他引：1  

于新凯  左群  赛因贺西格  孙庆文  陆爱云 《上海体育学院学报》2008,32(1):39-43

目的:研究运动对慢性心理应激大鼠延髓内皮素(ET)及其受体的影响,探讨延髓心血管中枢———头端腹外侧区和孤束核中内皮素及其受体在慢性心理应激过程中变化的意义和机制。方法:将雄性SD大鼠随机分为C组(对照组)、C S组(对照加游泳运动组)、R组(规则光—电刺激组)、I组(不规则刺激组,)、I S组(不规则光—电刺激加游泳运动组),建立运动对光—电刺激大鼠慢性心理应激影响模型。结果:慢性心理应激过程中,随着应激程度的提高,延髓心血管中枢的头端腹外侧区及孤束核ET含量逐渐下降,ETmRNA的表达变化方向与ET一致,提示慢性心理应激可导致中枢内相关部位ET表达的下调;与ET的变化趋势不同,应激程度的提高可使延髓心血管中枢的头端腹外侧区及孤束核ET受体ETR—A含量逐渐提高,游泳运动使受体的含量与ET含量更趋于合理,可防止在慢性心理应激过程中枢相关部位的过度兴奋或抑制,维持其调节心血管活动的正常功能。  相似文献   

跳远助跑最后1O米分段速度的研究     

赵国雄 《中国体育科技》1997,(Z1)

本文根据鲍威尔、刘易斯等优秀跳远运动员助跑最后10米分段速度的变化，指出最后5米助跑速度比第一段5米助跑速度快，它与快速起跳结合的技术，是当今跳远训练的发展方向。  相似文献   

Physical Inactivity,Obesity, and Type 2 Diabetes: An Evolutionary Perspective     

S. Boyd Eaton  Stanley B. Eaton 《Research quarterly for exercise and sport》2017,88(1):1-8

Physical inactivity (and unhealthy nutrition) has distorted body composition and, in turn, reordered the proportions of myocyte and adipocyte insulin receptors. Insulin acting on adipocyte receptors produces less glucose uptake than does comparable interaction with myocyte receptors. Accordingly, in individuals with disproportionate muscle/fat composition, any given glucose load requires greater-than-normal pancreatic insulin secretion for adequate disposal. This hyperinsulinemia then becomes the leading cause of type 2 diabetes (T2DM) as insulin-sensitive tissues become desensitized. Because T2DM is rooted in potentially reversible lifestyle factors, rather than focusing on the intricacies of glucoregulation at the molecular level and on testing new drugs to control blood sugar, this article calls for a new prevention and treatment paradigm, in which exercise and weight control are essential and for which an inexpensive and acceptably accurate measure of body muscle and fat proportions is needed.  相似文献   

Ⅴ型胶原蛋白ａ1链基因多态性与有氧耐力表型的关联性     

邓潇潇  杨贤罡  李燕春 《北京体育大学学报》2017,40(2):45-50

摘要：目的：通过分析Ⅴ型胶原蛋白ａ1链（COL5A1）基因多态性与60名中国北方汉族女子专业长跑运动员机能指标的关联性,探寻预测有氧耐力表型的分子标记。方法：采用联合测试法测得无氧阈和最大摄氧量相关指标,肺功仪测得肺功相关指标。用PCR-RFLP分析COL5A1基因的rs13946、rs12722多态性。结果：1）rs12722位点：不同基因型运动员之间无氧阈摄氧量、无氧阈摄氧量相对值有显著性差异（P<0.05）,TT型运动员显著大于CC和CT型。2）rs13946位点：该位点与有氧耐力表型以及肺功之间无关联（P<0.05）。3）rs13946-rs12722单体型：携带TC单体型运动员的无氧阈摄氧量和无氧阈摄氧量相对值指标均显著高于非TC单体型运动员（P<0.025）。结论：1）COL5A1 rs12722 TT基因型可作为预测中国北方汉族女子长跑运动员无氧阈强度下机体氧耗量的分子遗传学标记。2）TC单体型可作为预测北方汉族女子长跑运动员无氧阈摄氧量及其相对值指标的分子遗传学标记。  相似文献   

运动对RBP4诱导的脂代谢异常鼠肝脏ACC1 表达和脂肪合成的影响          下载免费PDF全文

张明军 《河北体育学院学报》2017,31(1):54-59

目的:研究运动对RBP4诱导的脂代谢异常鼠肝脏ACC1表达和脂肪合成的影响.方法:重组人RBP4注射建立脂代谢异常鼠模型.设一次性运动组(RBP4 One-time exercise group,ROE 组)、8周有氧运动组(RBP4 aerobic exercise group,RAE组)和安静对照组(RBP4 control group,RC组).结果:ROE组血清RBP4水平与RC组相比显著降低(P＜0.05),血清TG和肝脏TG含量无显著改变(P＞0.05).RAE组血清RBP4、TG和肝脏TG含量与RC组和ROE组相比均显著降低(P＜0.01).与RC组相比,ROE组和RAE组肝脏ACC1mRNA表达均显著降低(P＜0.01).与RC组相比,ROE组ACC1蛋白表达无显著改变(P＞0.05).与RC组和ROE组相比,RAE组ACC1蛋白表达均显著降低(P＜0.01).结论:高RBP4显著增加小鼠肝脏ACC1基因和蛋白表达增加,促进肝脏脂肪合成.8周有氧运动抑制了RBP4在肝脏的脂肪合成促进作用,改善脂代谢,机制涉及降低RBP4水平、减少肝脏ACC1基因和蛋白表达以及TG的合成.  相似文献   

The Saljuq Turks’ Conversion to Islam: The Crusading Sources     

Nicholas Morton 《Al-Masaq: Islam & the Medieval Mediterranean》2015,27(2):109-118

This article contributes to the important debate over the conversion of the Turks to Islam. Previously, it was thought that the Turks abandoned their former steppe faith and customs very swiftly to become staunch Sunni Muslims, but this view has recently been challenged by a number of studies. The current consensus seems to be that the Turks’ adoption of Islam was a process of far longer duration, spanning many decades. This article broadens this discussion by demonstrating that the chronicles written by the First Crusaders contain much useful information that is pertinent to this question. It works through these texts, showing that they can shed new light on this point.  相似文献   

8周间歇运动激活LIF-LIFR-STAT3信号和诱导骨骼肌细胞增殖     

贾单单  田振军  Shaojun Du 《北京体育大学学报》2017,40(10):44-49

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基于负样本多通道优化SSD网络的钢铁厂提取     

卢凯旋  李国清  陈正超  昝露洋  李柏鹏  高建威 《中国科学院大学学报》2020,37(3):352-359

准确提取钢铁厂对去产能监测和环境保护具有重要意义。传统的人工目视解译方法效率低、成本高,无法满足开展大区域钢铁厂监测的需求。以深度学习目标检测网络SSD为基础,构建面向遥感影像钢铁厂提取的深度学习目标检测网络,提出maxout模块,将负样本通路优化为多分支结构,突出难分负样本特征并提升网络对无用特征的抵制效果。利用国产GF-1数据对京津冀地区的钢铁厂进行快速自动提取实验。与人工解译的钢铁厂点位数据的对比表明,该目标检测方法的提取精度达到80%以上。  相似文献   

Why super sandstorm 2021 in North China?     

Zhicong Yin  Yu Wan  Yijia Zhang  Huijun Wang 《国家科学评论(英文版)》2022,9(3)

Severe sandstorms reoccurred in the spring of 2021 after an absence for more than 10 years in North China. The dust source area, located in Mongolia, suffered destructive cooling and warming in early and late winter, which loosened the land. A lack of precipitation, excessive snow melt and strong evaporation resulted in dry soil and exiguous spring vegetation. A super-strong Mongolian cyclone developed on the bare and loose ground, and easily blew and transported large amounts of sand particles into North China. Furthermore, top-ranking anomalies (sea ice shift in the Barents and Kara Sea, and sea surface temperatures in the east Pacific and northwest Atlantic) were found to induce the aforementioned tremendous climate anomalies in the dust source area. Analyses, based on large-ensemble Coupled Model Intercomparison Project Phase 6, yield results identical to the reanalysis data. Thus, the climate variabilities at different latitudes and synoptic disturbances jointly facilitated the strongest spring sandstorm over the last decade.  相似文献   

Transition of autophagy and apoptosis in fibroblasts depends on dominant expression of HIF-1α or p53     

Min LI  Yidan SU  Xiaoyuan GAO  Jiarong YU  Zhiyong WANG  Xiqiao WANG 《Journal of Zhejiang University. Science. B》2022,23(3):204

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