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41.
As one of the most popular novels in O’Connor’s works, Wise Blood is heated discussed by critics home and abroad. Wise blood, as the major image in the novel, flows in the body of both Hazel Motes and ... 相似文献
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43.
观察冰片对血脑屏障(BBB)P-糖蛋白功能的影响。取NIH小鼠,随机分为冰片高、中、低剂量组,维拉帕米组和溶剂对照组。灌胃给药,每日2次,共7次。末次给药后,分别从尾静脉和脑室注射罗丹明123(Rho-123)。注射Rho-123后取血浆和脑组织,荧光分光光度法测定血浆及脑组织中Rho-123含量。结果表明:尾静脉注射Rho-123后,冰片对小鼠血浆Rho-123含量无明显影响;5,10,20和30min冰片高、中剂量组小鼠脑组织Rho-123浓度均显著高于溶剂对照组(P0.01)。脑室注射Rho-123后5,10,20和30 min,冰片高剂量组小鼠血浆Rho-123浓度均显著低于溶剂对照组(P0.05);20,30min冰片中剂量组小鼠血浆Rho-123浓度亦显著低于溶剂对照组(P0.05);1,5,10和20 min冰片高剂量组小鼠脑组织Rho-123浓度显著高于溶剂对照组(P0.01或P0.05);5,10 min冰片中剂量组小鼠脑组织Rho-123浓度亦显著高于溶剂对照组(P0.05)。说明冰片能抑制BBB P-gp功能。 相似文献
44.
Patrick C.Y.WOO Samson S.Y.WONG Jade L.L.TENG Kit-Wah LEUNG Antonio H.Y.NGAN Herman TSE Susanna K.P.LAU Kwok-Yung YUEN 《Journal of Zhejiang University. Science. B》2010,11(6):391-401
A straight, non-sporulating, Gram-variable bacillus (HKU24T) was recovered from the blood culture of a patient with metastatic breast carcinoma. After repeated subculturing in BACTEC Plus Anaerobic/F blood culture broth, HKU24T grew on brucella agar as non-hemolytic, pinpoint colonies after 96 h of incubation at 37 °C in an anaerobic environment and aerobic environment with 5% CO2. Growth was enhanced with a streak of Staphylococcus aureus. HKU24T was non-motile and catalase-negative, but positive for alkaline phosphatase, β-glucosidase, and α-glucosidase. It hydrolyzed phenylphosphonate and reduced resazurin. 16S rRNA, groEL, gyrB, recA, and rpoB sequencing showed that HKU24T occupies a distinct phylogenetic position among the Leptotrichia species, being most closely related to Leptotrichia trevisanii. Using HKU24T groEL, gyrB, recA, and rpoB gene-specific primers, fragments of these genes were amplified from one of 20 oral specimens. Based on phenotypic and genotypic characteristics, we propose a new species, Leptotrichia hongkongensis sp. nov., to describe this bacterium. 相似文献
45.
赵汉芬 《襄樊职业技术学院学报》2010,9(3):28-29
对襄樊市区中老年人群70例的血糖进行检测,并与正常人群的血糖均值比较,50-59岁年龄组的血糖含量与全国水平相当(p〉0.05),而60岁以上年龄组血糖含量高于全国水平(p〈0.05)。提示血糖水平随着年龄增长而增高,发生糖尿病的潜在危险性较大。 相似文献
46.
Impact of Chronic Lead Exposure on Selected Biological Markers 总被引:1,自引:0,他引:1
Ambica P. Jangid P. J. John D. Yadav Sandhya Mishra Praveen Sharma 《Indian journal of clinical biochemistry : IJCB》2012,27(1):83-89
Lead poisoning remains a major problem in India due to the lack of awareness of its ill effects among the clinical community.
Blood lead, δ-aminolevulinic acid dehydratase (δ-ALAD) and zinc protoporphyrin (ZPP) concentrations are widely used as biomarkers
for lead toxicity The present study was designed to determine the impact of chronic lead exposure on selected biological markers.
A total of 250 subjects, of both sexes, ranging in age from 20 to 70 years, were recruited. On the basis of BLLs, the subjects
were categorized into four groups: Group A (BLL: 0–10 μg/dl), Group B (BLL: 10–20 μg/dl). Group C (BLL: 20–30 μg/dl) and Group
D (BLL: 30–40 μg/dl) having BLLs of 3.60 ± 2.71 μg/dl, 15.21 ± 2.65 μg/dl, 26.82 ± 2.53 μg/dl and 36.38 ± 2.83 μg/dl, respectively.
Significant changes in biological markers due to elevated BLLs were noted. The relation of BLL and biological markers to demographic
characteristics such as sex, habits, diet and substances abuse (smoking effect) were also studied in the present investigation.
Males, urban population, non-vegetarians, and smokers had higher blood lead levels. δ-ALAD activity was found to be significantly
lower with increased BLL (P < 0.001), while the ZPP level was significantly higher with increased BLL (P < 0.001). Further, BLL showed a negative correlation with δ-ALAD (r = −0.425, P < 0.001, N = 250) and a positive correlations with ZPP (r = 0.669, P < 0.001, N = 250). Chronic lead exposure affects the prooxidant-antioxidant equilibrium leading to cellular oxidative stress. 相似文献
47.
Alex Livy Sayhean Lye Chahil K. Jagdish Nurul Hanis Velapasamy Sharmila Lian Wee Ler Bagali Pramod 《Indian journal of clinical biochemistry : IJCB》2012,27(1):28-33
Buccal cell usage has been shown by many to be a cost effective and safe method to isolate DNA for various biological experiments
especially large epidemiological studies (Garcia-Closas et al. Cancer Epidemiol Biomarkers Prev 10:687–696, 2001). Non-invasive DNA collection methods are preferred over phlebotomy in order to increase study participation and compliance
in research centers and for sick patients in hospital settings. There have been conflicting reports about the methodology
and results obtained from using buccal DNA. It is not very clear if phlebotomy can be confidently replaced by buccal cell
DNA. It is often left for the user to take an intelligent decision. To address this issue, we compared the performance of
buccal and blood DNA from same subjects in a genotyping experiment and this paper reports the results. Cotton swab derived
buccal cells were scraped from the inner side of cheeks from 16 subjects, and blood was also drawn from the same 16 subjects
participating in a genotypic association study of a lipid disease. The DNA quality was assessed by resolving on agarose gels,
checking purity (A260/A280) and finally by microarray hybridization. This study showed that DNA degradation affects the total
yield and performance of the buccal DNA when compared to the blood DNA in microarray based genotyping. Genotyping results
can be seriously compromised if care is not taken to check the quality and yields of such specimens. 相似文献
48.
对运动员血红蛋白和血尿素氮测定值的分析 总被引:1,自引:0,他引:1
分析了每周训练课后的血红蛋白、血尿素氮的安静值以及一日变化幅度和冬、夏训期的变化,为今后疲劳监控提供了可行依据。 相似文献
49.
朱泳 《首都体育学院学报》2007,19(3):113-114
400m跑是一个既要求速度,又要求耐力的竞赛项目,因此,提到专项耐力,通常指的是400m跑所要求的速度耐力。速度和耐力是一对矛盾。对现代流行的400m专项耐力训练手段进行分析,用心率和血乳酸值作为监测指标,对能够有效锻炼运动员的专项耐力的训练手段进行筛选。结果表明,400m跑合100m走跑×10是有效锻炼运动员专项耐力的训练手段。同时,300m后的跑段对锻炼运动员乳酸耐受能力非常重要。 相似文献
50.
对参加全国冠军赛个人项目预决赛及接力项目预决赛的江苏省队游泳运动员血乳酸及成绩变化做了观察,发现个人项目中决赛成绩优于预赛,而血乳酸值决赛却低于预赛;接力项目随着决赛成绩的提高血乳酸值也升高。推测此现象与精神紧张有关。 相似文献