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Study on arsenic level in public water supply of Delhi using hydride generator accessory coupled with atomic absorption spectrophotometer 总被引：1，自引：0，他引：1
Sanjeev Lalwani T. D. Dogra D. N. Bhardwaj R. K. Sharma O. P. Murty 《Indian journal of clinical biochemistry : IJCB》2006,21(1):70-76
Exposure to arsenic has been associated with several health hazards. Worldwide the main reason for chronic human intoxication
with arsenic is intake of contaminated drinking water. Air acetylene type of atomic absorption spectrophotometer in combination
with hydride generator accessory was used to analyze arsenic level in 25 water samples collected from 25 booster pumping stations
and 313 water samples collected from tap water supply of 62 areas of Delhi. Results were analyzed using SPSS and Barlett’s
Chi Square Test. Mean arsenic level detected in water samples collected from booster pumping stations was 0.00976 ppm (Range
0.000–0.017 ppm, Standard Deviation 0.006 and Standard error of Mean 0.00118). Maximum arsenic level (0.017 ppm) was found
in water samples of booster pumping stations of Mehrauli, Punjabi Bagh and Ramjas Road. Mean arsenic level detected in samples
collected from tap water supply was 0.013 ppm (Range 0–0.0430 ppm, Standard Deviation 0.00911 and Standard error of Mean 0.000515).
In water samples of 42 areas arsenic level detected was exceeding WHO/EPA permissible limit of 0.01 ppm (10 ppb). The mean
arsenic level detected in water samples of booster pumping station was within WHO/EPA permissible limit while mean arsenic
level detected in tap water samples was marginally higher. Mixing of ground water and contamination through broken or leaking
channel could be the possible reason of higher arsenic level in tap water. Continuous monitoring of quality of drinking water
is required particularly in view of water contamination caused by industrial waste and uncontrolled ground water extraction. 相似文献
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Sanjeev Shruthi Molly Mary Thabah Bobby Zachariah Vir Singh Negi 《Indian journal of clinical biochemistry : IJCB》2021,36(2):185
To study oxidative stress in systemic lupus erythematosus (SLE) by estimating serum oxidised LDL (OxLDL), 8-hydroxy-2′-deoxyguanosine (8-OHdG), malondialdehyde (MDA), and total anti-oxidant status and to correlate with SLE disease activity and disease damage. Eighty SLE patients satisfying the Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) 2012 criteria and 80 healthy controls were studied. Exclusion criteria were infections, renal insufficiency, other connective tissue diseases, drug-induced lupus, smoking, alcohol consumption. Disease activity was measured by SLE disease activity index-2 K (SLEDAI), disease damage was quantified by SLICC-Damage Index (SDI). Sera was tested for OxLDL, 8-OHdG, and total antioxidant status (TAS) by double-antibody sandwich ELISA; MDA measured by Colorimetric assay. Oxidative stress markers were compared between group1- controls, group 2-mildly active SLE (SLEDAI ≤ 5), group 3- moderate to highly active SLE (SLEDAI ≥ 6). SLE patients had significantly higher MDA, 8-OHdG and lower TAS when compared to healthy controls, while OxLDL was similar in the three groups. MDA, 8-OHdG were significantly higher, TAS lower in group 3 compared to group 2. MDA had positive correlation with SLEDAI, TAS negatively correlated with SLEDAI. SLE with neuropsychiatric manifestations, vasculitis, anti-sdDNA antibodies had higher MDA, MDA/TAS ratio. SLE patients with thrombocytopenia, and vasculitis had higher OxLDL. Only OxLDL was significantly higher in those patients who have SDI > 1. SLE patients have increased oxidative stress measured by increases in MDA, 8-OHdG, and lower total antioxidant status that was associated with disease activity and some disease manifestations. However only OxLDL was associated with damage. 相似文献
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Study on arsenic level in ground water of Delhi using hydride generator accessory coupled with atomic absorption spectrophotometer 总被引：1，自引：0，他引：1
Sanjeev Lalwani T. D. Dogra D. N. Bhardwaj R. K. Sharma O. P. Murty Aarti Vij 《Indian journal of clinical biochemistry : IJCB》2004,19(2):135-140
Surveillance of drinking water is essentially a health measure intended to protect the public from water borne diseases. Hydride
generator accessory coupled with atomic absorption spectrophotometer was used to analyze arsenic level in 49 ground water
samples collected from different areas of Delhi. Arsenic level in ground water samples was in the range of 0.0170 to 0.100
ppm (Mean-0.0431, Standard Deviation-0.0136, Std. error of Mean-0.00194) with minimum concentration at Raney Well No. 7 (0.0170
ppm) and maximum at Kotla Mubarak Pur (0.100 ppm). Arsenic containing sediments and percolation of chemicals into soil as
the result of dumping of garbage rich in chemicals into open landfills could be the possible source of arsenic in ground water
of Delhi. Extensive survey and continuous monitoring is required to be made to assess the magnitude of problem and earlier
intervention. 相似文献
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Pradeep Sharma Neelima Singh Vinod Singh Sanjeev Singh Harsh vardhan Singh Sameer Gupta 《Indian journal of clinical biochemistry : IJCB》2006,21(1):205-207
Osteoarthritis of knee joints is a disease of old age in both sex. It is very common after the age of 40 years in elderly
females or in postmenopausal phase of females. It is characterized by narrowing of space in joints due to inflammation. The
exact mechanism of inflammation in this disease is not yet clear. Tumor necrosis factor alpha (TNF-α) may involve in onset
of disease. The present study is being carried out in 130 female subject of age group 40–60 years suffering from osteoarthritis
of knee joints and 50 normal healthy control female subjects. A correlation is made between TNF-α and estrogen and found significant
inverse correlation (r<0.001), between TNF-α and estrogen hormone in osteoarthritic female patients as compared to normal
healthy control female group. 相似文献
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Jyoti Aggarwal Akansha Singh Sanjeev Gupta Rajendra Prasad 《Indian journal of clinical biochemistry : IJCB》2021,36(1):120
Psoriasis is a common and an inflammatory skin disease. Trace elements play an important role in the skin metabolism such as keratinisation and melanin formation as well as immunological and inflammatory reactions. Henceforth, the present study was aimed to evaluate the essential metals with special reference to Cu and Zn. In this study, 72 psoriatic patients and 50 controls were enrolled. On the basis of PASI score psoriatic group comprising of 48 mild and 24 severe psoriatic patients were grouped. The serum trace elements analysis in the subjects revealed that serum Cu levels and Cu/Zn ratio was significantly higher in the psoriatic patients as compared to controls. Interestingly, severity of the psoriasis was well correlated with the serum Cu levels. Taking together, all these findings suggest that Cu may be a major culprit in the pathogenesis as well as in the severity of the disease. 相似文献
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Colloids play an important role in our modern lives. In this article, we briefly discuss various forces that are known to operate between colloidal particles and then take the reader through the discovery of a new, strong and long ranged force operating between hydrophobic particles/surfaces. Characteristics of the new force and some promising theories proposed in the literature to explain its origin are also discussed; the origin of the new force is not yet resolved, however. 相似文献
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Attitudes and concerns of pre-service teachers regarding inclusion of students with disabilities into regular schools in Pune,India 总被引：1，自引：1，他引：0
Umesh Sharma Dennis Moore Sanjeev Sonawane 《Asia-Pacific Journal of Teacher Education》2009,37(3):319-331
Attitudes and concerns of pre-service teachers regarding implementation of inclusive education were examined. The participants consisted of 480 pre-service teachers enrolled in a one year Bachelor of Education (B.Ed) program at Pune University, in the state of Maharashtra. The results of the study showed that participants had somewhat negative attitudes and a moderate degree of concern regarding the inclusion of students with disabilities in their classes. Participants with higher level of education (i.e. postgraduate degrees) were found to have significantly more positive attitudes compared to their counterparts. Perceived level of confidence in teaching students with disabilities was also associated with lower degree of concerns amongst participants. The results are discussed with possible implications for university educators and policy makers. 相似文献
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Abbas Ali Mahdi Anu Chandra Raj Kumar Singh Sanjeev Shukla L. C. Mishra Sohail Ahmad 《Indian journal of clinical biochemistry : IJCB》2003,18(2):8-15
In the present study the antioxidative potential ofMomordica charantia, Azadirachta indica, Allium sativum andOcimum sanctum was assessed in streptozotocin induced diabetic rats. Lipid peroxide levels were also measured in normal, diabetic and treated
animals. Malondialdehyde (MDA) levels were significantly higher and antioxidant activity was found low in diabetic groups
as compared to the control groups, and significant alteration in both the MDA levels and antioxidant activity was also observed
when the above herbal hypoglycemic agents were given to diabetic rats. On the basis of our results we conclude thatM. charantia, A. indica, A. sativum andO. sanctum are not only useful in controlling the lipid peroxide levels but are also helpful in further strengthening the antioxidant
potential. 相似文献