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采用白藜芦醇(Res)和富勒烯(C60)结合制备Res/C60纳米组装体并验证其安全性和抗炎性。通过扫描电子显微镜(SEM)、拉曼光谱和X射线衍射研究了纳米组装体形貌、粒径大小及波谱峰值特征。其次,通过紫外分光光度法研究了Res的药物缓释行为。最后,通过MTT法在人脐静脉内皮细胞(HUVECs)层面验证了Res/C60纳米组装体的安全性以及体外的抗炎性。研究发现,Res/C60纳米组装体呈短棒状,横截面平均直径为(379.74±33.47)nm。拉曼光谱和X射线衍射特征峰显示Res/C60纳米组装体被成功制备。Res/C60纳米组装体的聚氨酯(PU)涂层中Res药物在30 d内累积释放量可达60%左右。胆管支架涂层对HUVECs细胞毒性较低,且通过释放Res可显著抑制炎症因子的释放。 相似文献
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为了适应新形势下卫生改革的需要,推进医院各项事业的快速发展,确保医院各项任务的顺利完成,加快后勤改革已势在必行。后勤改革的目的是提高工作效率,满足临床第一线的需要,增收节支,提高经济效益,以促进医院可持续发展。医院后勤社会化是利用社会力量向医院提供后勤服务的方向,也是目前医院管理体制改革的重要内容之一,是医院后勤管理的重要方向。医院后勤社会化有利于提高后勤人员的劳动生产率,有利于提高服务质量和服务水平,更好地促进医院改革发展。 相似文献
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西藏山南人民医院创建于1956年7月,医院从无到有,从小到大,如今走过了50个春秋。50年来,在山南地委和行署的亲切关怀下,在院党委、院部正确领导下,医院在社会效益、管理体制、服务质量、经济效益等方面均发生了显著的变化,取得了辉煌的业绩,现已发展成为集医疗、保健、急救等一体的综合性医院,承担着全区33万人民的急、危、重症诊治工作. 相似文献
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临床药学专业培养的目标是既要懂医又要懂药的专门人才——临床药师。分析临床药学实验教学现状,针对临床药师的工作需要和学生的实践能力的提高,提出新型临床药学实验教学模式的构建与思考。 相似文献
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2019新冠肺炎疫情给国家系统带来灾难,却为国民体育锻炼系统摒除了阻碍因素,同时引发外部大量优质体育锻炼信息有效触达国民,成为体育锻炼系统一个有利的教育、传播和发展机遇。据此提出:认清局面,有计划、有目的地扩大优质信息资源流入,增强国民锻炼意识;通过加大教育渗透、创设时间和空间上易获得通路、丰富可参与项目群落、发挥团体互助优势、鼓励居家简易参与等方式,做好疫后锻炼意识和行为的巩固加强准备,借助突发事件推动国家全民健身事业的发展。 相似文献
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Kim Viel‐Ruma David E. Houchins Kristine Jolivette Laura D. Fredrick Robert Gama 《Learning disabilities research & practice》2010,25(2):97-108
Students with disabilities often struggle with writing tasks. In order to improve the written expression performance of high school students with deficits in written expression, a Direct Instruction writing program was implemented. The participants were six high school students in programs for individuals with learning disabilities. Three of the six students were served in programs for students who are English Language Learners. Using a multiple‐probe across‐participants design, the effect of the writing program was examined. The intervention was implemented over a 5‐week period with maintenance checks conducted 2 and 4 weeks after the termination of instruction. Results were variable, but there appeared to be a positive trend in student writing performance as measured by correct word sequence, length of text, and the TOWL‐3. Implications for practice and future directions are also provided. 相似文献
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Elizabeth M. P. Gama 《Int J Intercult Relat》1977,1(4):46-59
This is a pilot study on the readjustment problems of Brazilians returned from graduate study in the United States. Subjects were 31 former LASPAU scholars who were interviewed by the senior author after they were back in Brazil. The family and professional problems they experienced as they tried to readjust to life in their country were investigated, as well as the intensity of these problems and the adequacy of coping, as perceived by the respondent. Taped interviews were coded independently twice, over a 16-month interval. High reliability levels were obtained. Results indicated that returnees had little difficulty adjusting to life with their families except for experiencing some value conflict with them and some lack of privacy. Most of their problems were related to their professional life. In that category they reported that they found some difficulty adjusting to the system as a whole and to their role as professors. Lack of intellectual stimulation, lack of facilities and materials, excessive red tape, lack of opportunity and time to do research was fairly common for most, and they felt these were moderately serious problems. In most cases returnees felt they were coping adequately. 相似文献