Modellierung und kartographische Visualisierung von Geodaten mit XML-basierten Sprachen     

Brigitte Mathiak  Andreas Kupfer und Karl Neumann 《Informatik - Forschung und Entwicklung》2005,20(1-2):24-32

Zusammenfassung Mit den XML-basierten Sprachen GML, XSLT und SVG lassen sich Geodaten nicht nur anwendungsorientiert modellieren, sondern auch karten?hnlich visualisieren. In dieser Fallstudie zeigen wir das, indem wir realistische Geodatenbest?nde der Landesvermessungs?mter zun?chst mit der Geography Markup Language (GML) nachmodellieren. So mit GML strukturierte Daten werden dann mit der Extensible Stylesheet Language for Transformation (XSLT) auf Elemente der Sprache Scalable Vector Graphics (SVG) abgebildet. Dabei wird der Prozess der kartografischen Visualisierung durch XSLT-Konstrukte modelliert und auch gleichzeitig implementiert. Als Ergebnis erhalten wir Grafiken, die den entsprechenden Karten der Landes?mter zumindest nicht un?hnlich sind.

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Using the XML-based languages GML, XSLT and SVG, we modeled German geo data and also visualized it in map-like graphics. This case study shows the feasibility of that approach, by modelling the data with the Geography Markup Language (GML). Then, the GML-structured data is mapped with the Extensible Stylesheet Language for Transformation (XSLT) to elements of the language Scalable Vector Graphics (SVG). The process of cartographical visualization is thus modelled through XSLT-constructs and at same time also implemented. The results are graphics, which share close ressemblance to the corresponding maps of the official offices.

CR Subject Classification I.3.3,I.3.5,I.6.5,I.7.2,J.2  相似文献   

Long-term endurance training increases serum cathepsin S and decreases IL-6 and hsCRP levels     

Michael Sponder  Ioana-Alexandra Campean  Michael Emich  Monika Fritzer-Szekeres  Brigitte Litschauer  Jutta Bergler-Klein 《Journal of sports sciences》2017,35(21):2129-2134

Cathepsin S (CS) was shown to play a key role in cancer progression, atherosclerosis, heart valve disease, insulin resistance and diabetes mellitus. The present prospective study aimed to investigate the influence of sports on CS, interleukin-6 (Il-6) and high-sensitivity C-reactive protein (hsCRP) levels.

Ninety-eight of 109 participants completed the study. Ergometries were performed at baseline and after 8 months to evaluate/quantify the performance gain. Blood samples were taken at baseline and every 2 months. CS was measured by ELISA (enzyme-linked immunosorbent assay). Compared to the control group (mean performance gain ?3.41 ± 4.62%) we observed a significant physical-activity-induced increase of CS levels (3.45–3.73 ng · ml^?1; P = 0.027) and a significant decrease of Il-6 (2.43–1.91 pg · ml^?1; P = 0.031) and hsCRP-levels (0.11–0.09 mg · dl^?1; P = 0.001) in the intervention group (mean performance gain: 12.13 ± 6.32%). Furthermore, the tendency of the progression was significant for CS and Il-6 (P = 0.002/0.033).

We could show a significant sports-induced decrease of the classic inflammation parameters hsCRP/Il-6, probably expressing a downregulation of permanently prevalent inflammation processes. Simultaneously CS levels increased significantly. Our results show that increasing CS amounts are not simply to equal with an enhanced inflammation status and might even have beneficial effects on inflammation and angiogenesis.  相似文献   

WIDENING ACCESS TO UNIVERSITIES WHILE IMPROVING THE QUALITY OF TEACHING?     

Brigitte Berendt 《Higher Education in Europe》1993,18(1):48-57

After the Federal Constitutional Court, in 1976, had confirmed the personal right of access to universities, political discussions to “open up Higher Education” (Öffnung der Hochschulen)intensified. Specific laws and regulations were passed relative to the mobilization of all capacities. During the following years, the number of first‐year students grew in an unforeseen way, but the percentage of graduates decreased. In 1986, intensive activities for analyzing the situation and for developing solutions for numerous problems began; however, an anticipated “Educational Summit conference” has been postponed by the Chancellor of the Federal Republic of Germany to the summer of 1993. The interests which are in conflict concern mainly the democratization of higher education (including the individual right of access), responses to future needs, budget cuts, and the improvement of the quality of teaching. This article surveys the development of the problem, describes activities for analyzing the situation and the development of solutions, and suggests perspectives for future developments.  相似文献   

Studienförderung für Auslandsstudien     

Brigitte Kofler 《Zeitschrift für Hochschulrecht, Hochschulmanagement und Hochschulpolitik: zfhr》2008,7(3):81-90

In der Entscheidung Morgan und Bucher hat der Europäische Gerichtshof zwei Regelungen des deutschen Bundesausbildungsförderungsgesetzes zur Ausbildungsförderung für Auslandsstudien als gegen die Freizügigkeit der Unionsbürger nach Art 18 EGV verstoßend und somit gemeinschaftsrechtswidrig angesehen. Das Urteil unterstreicht die Bedeutung, die der Gerichtshof der Freizügigkeit und der Gleichbehandlung von Unionsbürgern im Bildungsbereich zuerkennt. Dies wird von Österreich auch bei Klärung der Hochschulzugangsproblematik zu berücksichtigen sein. Das durch eine Novelle zum österreichischen Studienförderungsgesetz eingeführte Mobilitätsstipendium ist entsprechend den vom Europäischen Gerichtshof in Morgan und Bucher entwickelten Grundsätzen am Gemeinschaftsrecht zu messen.  相似文献   

A Report on the Further Training of Teachers in Media Education     

Brigitte Hipfl  W. Schludermann 《Learning, Media and Technology》1985,11(1):23-31

Because of media developments discernible in recent years and those foreseeable in the future, media education has to be looked upon as an absolute necessity. To be able to make media education a reality in schools (which, in this field, are undeniably the most important social institution for young people), the lack of training of teachers in that field has to be remedied. The continued training of teachers in media education described in this contribution must be seen against this background. Within limitations as to region and school levels it was directed at a group of schoolteachers in the province of Carinthia. After some general remarks on media education, the aims and contents as well as the organisation of the course are described.  相似文献   

Small and big publishers in France: Is literature a rare species?     

Brigitte?Ouvry-VialEmail author 《Publishing Research Quarterly》2003,19(1):31-44

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The argument for the self-government and public support of science in Weimar Germany     

Brigitte Schroeder-Gudehus 《Minerva》1972,10(4):537-570

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Preface to Special Topic: Microfluidics in Drug Delivery     

Brigitte Stadler 《Biomicrofluidics》2015,9(5)

In this special topic of Biomicrofluidics, the importance of microfluidics in the field of drug delivery is highlighted. Different aspects from cell-drug carrier interactions, delivery vehicle assembly to novel drug delivery devices are considered. The contributing reviews and original articles illustrate the synergistic outcomes between these two areas of research with the aim to have a positive impact on biomedical applications.Microfluidics is certainly one of the huge success stories when it comes to anticipated impact and fulfilled promises in academic research environments. Microfluidic approaches are game changers in many disciplines in natural science, including (bio)medical science. In the latter case, the fields of biosensing/diagnostics, tissue engineering, and drug discovery/delivery have benefited from concepts which allow for the fast throughput manipulation of fluids at the submillimeter length scale.A key aim in microfluidic-assisted drug discovery is the development of strategies which will facilitate the identification of potential “hits”—new drugs with the anticipated therapeutic benefit. In this context, “organ(disease)-on-chips” are considered as highly sophisticated in vitro models with lower cost and less ethical issues compared to extensive testing in animals. This technology is still very young with countless research challenges to be addressed and eventually overcome, but the few current reports are promising, and include “gut-on-chip,” “cancer-on-chip,” or “blood vessel-on-chip.” Additionally, intravenously injected drug delivery vehicles are exposed to the blood stream and the induced mechanical forces which are likely to affect their interaction with cells and tissue. Therefore, understanding the diffusion phenomena of biomolecules in microfluidic devices as reviewed by Yesil-Celiktas and coworkers in the current special content is crucial.¹ What is more, the contribution by Hosta-Rigau and colleagues provides a comprehensive overview over the interaction of drug carriers and cells in microfluidic-based systems which deliver a simple, but yet more realistic model of the dynamic in vivo situation.² Further, to illustrate the relevance of shear stress when assessing the potential of nanocarriers for drug delivery applications, we assembled novel block copolymers consisting of poly(cholesteryl acrylate) as the hydrophobic core and poly(N-isopropylacrylamide) as the hydrophilic extensions together with lipids into vesicles using the evaporation-rehydration method.³ Following on, we biologically evaluated the assemblies with applied shear stress using macrophages. In a related report by the Chakraborty group, a biocompatible acoustic microfluidic system was outlined including the effect of microbubbles with the applied acoustic field on biological cells.⁴From a different perspective, droplet microfluidics has become a popular method to assemble a huge diversity of particles of different size, shape, and morphology equipped with options for active or passive drug release. Microfluidics provides unique opportunities and flexibility to fabricate decent amounts of mono-disperse drug carriers using monomers, polymers, lipids, or inorganic precursor materials as building blocks. The assembly of size-tunable polymer/lipid particles by Sun et al.,⁵ and the fabrication of poly (lactic-co-glycolic acid) nanoparticles incorporated within poly (ethylene glycol) (PEG) microgels by the Chen group,⁶ provide interesting examples in this context. Further, artefacts associated with this technique have to be addressed and understood to avoid inaccurate and misleading data as reported by Litten et al.⁷ Microfluidic techniques can also be employed for cell encapsulation. Fan et al. demonstrated the trapping of human colon cancer cells in hydrogel particles with preserved viability and response to inflammatory stimuli.⁸Novel drug delivery devices which consider microfluidic concepts and set-ups are an interesting addition to traditional approaches. Implantable drug delivery systems provide an alternative to ensure constant drug level in blood without relying on the compliance of the patient while circumventing challenges involved in oral drug delivery coming from drug instability or limited absorbance among others. Yi and coworkers propose a reservoir approach in combination with a heat responsive valve towards the long term delivery of solid drugs.⁹ What is more, nebulizers, as alternative to inhalers for pulmonary drug delivery, suffer from miniaturization and drug degradation issues. Cortez-Jugo et al. report on a novel portable acoustomicrofluidic device, which successfully nebulized monoclonal antibodies into a fine aerosol mist including the first positive biological evaluation.¹⁰Further, combining microfluidics with sensing concepts as illustrated by Knoll and coworker¹¹ is of importance, since the design of drug delivery vehicles strongly relies on the fundamental understanding of the interaction between biomolecules, cells, and tissue.Taken together, these articles give an overview over the use of microfluidics in the area of drug delivery, which goes beyond the assembly of drug carries, but also provides a platform for their biological evaluation or the design of entirely new drug delivery devices. I hope that this collection of articles will stimulate new ideas and future collaborations between engineers/chemists/physicist and biologists towards the common goal to provide solutions for biomedical challenges. Finally, I would like to thank Professor Leslie Yeo for the invitation to be the guest editor for this special topic, and Christine Urso and other editorial and production staffs of Biomicrofluidics for making it a reality.  相似文献   

IMPROVING TEACHING AND LEARNING IN AFRICAN UNIVERSITIES ‐‐ STAFF (FACULTY) DEVELOPMENT PROGRAMMES AS A FIELD OF CO‐OPERATION BETWEEN EUROPEAN AND AFRICAN UNIVERSITIES     

Brigitte Berendt 《Higher Education in Europe》1989,14(2):69-75

In virtually all the countries of the world, the need for staff‐development programmes for university and other higher education teachers has been recognized. Because the developed countries of Europe and of North America have a head start in the domain, specialists from these countries have frequently been called upon to create and to offer staff‐development programmes in the universities of developing countries. This article discusses the appropriateness of European conceptions of staff‐development for African universities. Concluding that Euro‐centric staff‐developers and pre‐packaged European programmes are not appropriate, that they run the risk of becoming a form of cultural neo‐colonialism, the author considers ways in which European specialists can collaborate with their African colleagues in the structuring of staff‐development programmes that are not only African‐centred but are geared to the real needs of African universities as they are perceived by Africans themselves. If the author's suggestions are accepted, African universities will be able to make use of those aspects of European staff‐development concepts and programmes which have universal value without having to accept European cultural tutelage along with them.  相似文献   

National Assessments: Underlying Cultural Values Revealed by Comparing English and French National Tests     

Claire Planel  Patricia Broadfoot  Marilyn Osborn  Keith Sharpe  & Brigitte Ward 《European Journal of Education》2000,35(3):361-374

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