Carnosine in health and disease     

Guilherme Giannini Artioli  Craig Sale  Rebecca Louise Jones 《European Journal of Sport Science》2019,19(1):30-39

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   

In search of human uniqueness     

Elsa Addessi 《Metascience》2011,20(3):533-536

  相似文献   

Resting Bradycardia,Enhanced Postexercise Heart Rate Recovery and Cardiorespiratory Fitness in Recreational Ballroom Dancers     

Carlos Janssen Gomes da Cruz  Guilherme Eckhardt Molina  Luiz Guilherme Grossi Porto  Luiz Fernando Junqueira Jr 《Research quarterly for exercise and sport》2017,88(3):371-376

Purpose: In a cross-sectional study design, we evaluated the resting heart rate (HR_baseline) and exercise and postexercise stress test-related chronotropic responses in male practitioners of recreational ballroom dancing (BD; n = 25, M_age = 26.6 ± 6.1 years) compared to a control group of insufficiently active nondancers (CG; n = 25, M_age = 25.9 ± 4.5 years). Method: All participants underwent a submaximal exercise test. At 85% of the maximal predicted HR, the recovery protocol was started, and heart rate recovery (HRR) was recorded during 1-min intervals for 5 min. Results: Compared with CG, BD showed lower HR_baseline (70 beats per minute [bpm] vs. 62 bpm, respectively, U = 143, p < .05, ES = .46), lower preexercise HR (94 bpm vs. 86 bpm, U = 157, p < .05, ES = .42), longer exercise test duration (346 s vs. 420 s, U = 95.5, p < .05, ES = .59), and higher HRR for 5 min postexercise (U = 1.29–1.89, p < .05, ES = .33–.50) as follows: 1st min (32 bpm vs. 40 bpm), 2nd min (45 bpm vs. 53 bpm), 3rd min (51 bpm vs. 58 bpm), 4th min (55 bpm vs. 59 bpm), and 5th min (59 bpm vs. 63 bpm). The coefficient of HRR from the 1st min to the 5th min postexercise was similar in both groups (U = 229–311, p > .05, ES = < .10–.22). Conclusion: Heightened cardiovascular functional status characterized by favorable enhanced chronotropic dynamics appears to occur in practitioners of recreational ballroom dancing, which suggests that this modality of exercise may result in health benefits.  相似文献   

Ideology or reality? The awareness of educational aims and activities amongst German and Norwegian participants of the first summer and winter Youth Olympic Games     

Jörg Krieger  Elsa Kristiansen 《Sport in Society》2016,19(10):1503-1517

This paper explores the awareness of the young German and Norwegian participants in the Youth Olympic Games (YOG) of the additional educational mission of this new event, implemented by the International Olympic Committee. Among the questions considered are whether the nature of the event contradicts its claimed intention to focus on both competition and education. Data were collected through a set of interviews with young German and Norwegian athletes at the Singapore YOG in the summer of 2010 and the Innsbruck YOG in the winter of 2012. The findings revealed (1) a focus on elite sport by athletes and their coaches, while the educational aims were considered secondary; (2) that it was problematic for the young participants to focus on education in a high-performance event. The overall conclusion was that the YOG have had only limited success in achieving the educational ambitions of the Olympic Movement.  相似文献   

Paving the Olympic Dream: The Politics of the 2007 Pan-American Games in Rio de Janeiro     

Guilherme Nothen 《国际体育史杂志》2016,33(1-2):203-216

Abstract

The making of the 2007 Pan-American Games, held in the city of Rio de Janeiro, marked the beginning of the long transformation that this city would undergo in connection to sports mega-events. This paper revisits how the 2007 Pan-American Games were largely produced under the promise that its legacies, particularly the infrastructural ones, could be effectively mobilized in order to strengthen the chances of bringing the Olympics to Brazil for the first time. Whereas this rhetoric has proven somewhat successful in helping the city to secure the right to host the 2016 Olympics, the alleged connection between both events has shown to be much more limited than its proponents had initially advertized. In reality, most of the venues constructed for the Pan-American Games had to be thoroughly renovated for the Olympics, while some of them presented structural problems and/or failed to meet the standards imposed by international sports federations.  相似文献   

Winning the Battle,Losing the War: Bilingual Teachers and Post-Proposition 227     

Valdez  Elsa O. 《The Urban Review》2001,33(3):237-253

The implementation of Proposition 227 has created chaos, uncertainty, and a hostile environment for bilingual education teachers. This study describes the experiences of 20 bilingual education teachers in Southern California. In in-depth interviews, teachers speak out about the challenges, frustrations, fears, and the increasing animosity they face on a daily basis, and how they resist and contest the language enforcer role in various ways. Out of the chaos that has been created by Proposition 227, these bilingual teachers have emerged as the language civil rights activists of the new millennium.  相似文献   

Gender,Science and Technology in Brazil     

Plonski GA  Saidel RG 《Minerva》2001,39(2):217-238

This essay considers gender in relation toBrazilian science and technology. It reviewsleading studies in the field, and offers briefbiographies of pioneering women in science.While there is still much room for improvement,the essay suggests that the situation of womenin science experienced significant progressduring the closing decades of the twentiethcentury.  相似文献   

Effectiveness of Spanish intervention for first-grade English language learners at risk for reading difficulties   总被引：1，自引：0，他引：1  

Vaughn S  Linan-Thompson S  Mathes PG  Cirino PT  Carlson CD  Pollard-Durodola SD  Cardenas-Hagan E  Francis DJ 《Journal of learning disabilities》2006,39(1):56-73

The effectiveness of an explicit, systematic reading intervention for first-grade students whose home language was Spanish and who were at risk for reading difficulties was examined. Participants were 69 students in 20 classrooms in 7 schools from 3 districts who initially did not pass the screening in Spanish and were randomly assigned within schools to a treatment or comparison group; after 7 months, 64 students remained in the study. The intervention matched the language of instruction of their core reading program (Spanish). Treatment groups of 3 to 5 students met daily for 50 min and were provided systematic and explicit instruction in oral language and reading by trained bilingual intervention teachers. Comparison students received the school's standard intervention for struggling readers. Observations during core reading instruction provided information about the reading instruction and language use of the teachers. There were no differences between the treatment and comparison groups in either Spanish or English on any measures at pretest, but there were significant posttest differences in favor of the treatment group for the following outcomes in Spanish: Letter-Sound Identification (d = 0.72), Phonological Awareness composite (d = 0.73), Woodcock Language Proficiency Battery-Revised Oral Language composite (d = 0.35), Word Attack (d = 0.85), Passage Comprehension (d = 0.55), and two measures of reading fluency (d = 0.58-0.75).  相似文献   

The ‘invention’ of FIFA history: João Havelange’s election to FIFA presidency as a historic event     

Luiz Guilherme Burlamaqui 《Soccer & Society》2019,20(7-8):1056-1070

ABSTRACT

In 1974, the Brazilian sports official João Havelange was elected FIFA’s president in a two-round election, defeating the incumbent Stanley Rous. The upset, often attributed to a successful alliance with Asia, the Middle East and Africa, what at the time was referred to as the Third World – surprised observers everywhere. Here, the election can be analysed as a historically relevant event of social significance. It can be thought of as a political window by means of which the international dynamic of a specific moment in the Cold War can be perceived, especially the limitations and potentialities of the agency available to periphery countries at that time. In this article, I intend to discuss the narratives that forged the history of FIFA, which take this political ‘event’ as a key in the institution’s own historical transformation. The sources analysed will be mainly FIFA official histories, such as the FIFA News, FIFA historical books and movies about the history of FIFA.  相似文献   

Effects of Different Chair-Based Exercises on Salivary Biomarkers and Functional Autonomy in Institutionalized Older Women     

Taís Rieping  Guilherme Eustáquio Furtado  Matheus Uba Chupel  Juan C. Colado  Eef Hogervorst 《Research quarterly for exercise and sport》2019,90(1):36-45

Purpose: The aim of this study was to test the effects of chair-based exercise programs on salivary stress hormones, physical fitness, and functional autonomy of institutionalized older women. Method: In total, 47 participants (80 ± 8.04 years old) were recruited and allocated into three groups: chair-based aerobic exercises (CAE, n = 19), chair-based elastic-band strength exercises (CSE, n = 15), and a control group (CG, n = 13). A 14-week exercise intervention was done for the CAE and CSE groups, two times per week, in no consecutive days. Members of the CG did not participate in any type of exercise but kept their regular lifestyle. Fear of falling, autonomy, physical fitness, salivary cortisol, and alpha-amylase levels were assessed before and after the intervention. Results: The CAE group improved upper and lower body strength, agility–dynamic balance, and autonomy, with fear of falling decreasing significantly (p < .05, moderate effect size). Both exercise groups showed a trend toward an increase in salivary alpha-amylase levels (CAE = 43%, d = .31, and CSE = 44%, d = .41). Conclusion: Both exercise programs were able to improve functional autonomy, even in elders older than 80 years of age. It might be interesting to investigate the effectiveness of combining both aerobic and strength exercises in a unique protocol. The modulation effect of exercise in the hormonal responses needs to be further explored.  相似文献