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Biljak VR Ozvald I Radeljak A Majdenic K Lasic B Siftar Z Lovrencic MV Flegar-Mestric Z 《Biochemia medica : ?asopis Hrvatskoga dru?tva medicinskih biokemi?ara / HDMB》2012,22(1):86-91
Introduction
The aim of the study was to present a protocol for laboratory information system (LIS) and hospital information system (HIS) validation at the Institute of Clinical Chemistry and Laboratory Medicine of the Merkur University Hospital, Zagreb, Croatia.Materials and methods:
Validity of data traceability was checked by entering all test requests for virtual patient into HIS/LIS and printing corresponding barcoded labels that provided laboratory analyzers with the information on requested tests. The original printouts of the test results from laboratory analyzer(s) were compared with the data obtained from LIS and entered into the provided template. Transfer of data from LIS to HIS was examined by requesting all tests in HIS and creating real data in a finding generated in LIS. Data obtained from LIS and HIS were entered into a corresponding template. The main outcome measure was the accuracy of transfer obtained from laboratory analyzers and results transferred from LIS and HIS expressed as percentage (%).Results:
The accuracy of data transfer from laboratory analyzers to LIS was 99.5% and of that from LIS to HIS 100%.Conclusion:
We presented our established validation protocol for laboratory information system and demonstrated that a system meets its intended purpose. 相似文献2.
Milica Pejovic Milovancevic Milica Jovicic 《Emotional and Behavioural Difficulties》2013,18(3):261-269
It has been estimated that 9 to 13% of children and adolescents have a mental disorder that causes significant functioning impairment and that only one fifth of those who need mental health services actually receive them. The majority of children and adolescents are enrolled in schools, where they spend a considerable amount of time, and this is followed by the increasing efforts to establish collaboration between mental health professionals and school personnel. The role of mental health professionals is crucial in improving children’s mental health, as well as for providing better response to parents, educational staff and other agencies. There are several ways for a child psychiatrist to reach children and adolescents in a school setting: through individual student consultations (case consultations), through consultations to schools on general mental issues (systems consultations) and through promotion of mental health by creating and demonstrating evidence-based programmes for children, parents, school staff and others who are involved in child’s care. In order to achieve these goals, we need to establish partnerships and to define roles among organisations and individuals in the wider school environment, such as schools and school management, municipal authorities and administration, media, police, social welfare centres, health centres, parents and youth associations. 相似文献
3.
Aarash Sofla Bojana Cirkovic Anne Hsieh Jason W. Miklas Nenad Filipovic Milica Radisic 《Biomicrofluidics》2013,7(1)
The majority of available cardiomyocyte markers are intercellular proteins, limiting our ability to enrich live cardiomyocytes from heterogeneous cell preparations in the absence of genetic labeling. Here, we describe enrichment of live cardiomyocytes from the hearts of adult mice in a label-free microfluidic approach. The separation device consisted of a vertical column (15 mm long, 700 μm diameter), placed between permanent magnets resulting in a field strength of 1.23 T. To concentrate the field at the column wall, the column was wrapped with 69 μm diameter nickel wire. Before passing the cells through the column, the cardiomyocytes in the cell suspension had been rendered paramagnetic by treatment of the adult mouse heart cell preparation with sodium nitrite (2.5 mM) for 20 min on ice. The cell suspension was loaded into the vertical column from the top and upon settling, the non-myocytes were removed by the upward flow from the column. The cardiomyocytes were then collected from the column by applying a higher flow rate (144 μl/min). We found that by applying a separation flow rate of 4.2 μl/min in the first step, we can enrich live adult cardiomyocytes to 93% ± 2% in a label-free manner. The cardiomyocytes maintained viability immediately after separation and upon 24 h in culture. 相似文献
4.
Slađana Popović Nikola Unković Gordana Subakov Simić Milica Ljaljević Grbić 《文物保护研究》2018,63(5):292-302
The presence of biofilms on stone monuments can lead to biodeterioration processes that significantly lower not only the aesthetic value of cultural heritage sites but also cause considerable physical and chemical damage to stone surfaces. In terrestrial environments, cyanobacteria have a significant role in biofilm formation on a variety of natural and artificial stone substrata, including granite, sandstone, limestone, lime mortar, etc. Studies on cyanobacterial diversity and estimation of biodeteriorative activity on stone cultural heritage objects can be very important for conservators and restorers, and cyanobacteria removal from stone monuments is currently a great challenge for conservation science. In that sense, the diversity of terrestrial cyanobacteria was investigated at six localities in Serbia. Samples for cyanobacterial analyses were taken from surface biofilms covering different substrata: granite and lime mortar (The Monument to the Unknown Hero), sandstone (Branko's Bridge, Eiffel’s Lock) and carbonate rock (Medieval tombstones from Mramorje and Rasti?te, Gradac Monastery). A total of 18 cyanobacterial taxa were identified. The highest diversity was found on carbonate rock, followed by sandstone. Cyanobacteria were also recorded on an artificial substratum – lime mortar, while cyanobacteria were not found on granite. All detected cyanobacteria seriously impaired the structural and aesthetic integrity of the studied monuments via mechanical and chemical actions, so their presence must not be overlooked. 相似文献
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Round or rectangular tables for collaborative problem solving? A multimodal learning analytics study
Milica Vujovic Davinia Hernández-Leo Simone Tassani Daniel Spikol 《British journal of educational technology : journal of the Council for Educational Technology》2020,51(5):1597-1614
The current knowledge of the effects of the physical environment on learners’ behaviour in collaborative problem-solving tasks is underexplored. This paper aims to critically examine the potential of multimodal learning analytics, using new data sets, in studying how the shapes of shared tables affect the learners’ behaviour when collaborating in terms of patterns of participation and indicators related to physical social interactions. The research presented in this paper investigates this question considering the potential interplay with contextual aspects (level of education) and learning design decisions (group size). Three dependent variables (distance between students, range of movement and level of participation) are tested using quantitative and qualitative analyses of data collected using a motion capture system and video recordings. Results show that the use of round tables (vs rectangular tables) leads to higher levels of on-task participation in the case of elementary school students. For university students, different table shapes seem to have a limited impact on their levels of participation in collaborative problem solving. The analysis shows significant differences regarding the relationship between group size and the distance between students, but there is no substantial evidence that group size affects the level of participation. The findings support previous research highlighting the importance of studying the role of the physical environment as an element of learning design and the potential of multimodal learning analytics in approaching these studies. 相似文献
7.
Bayesian methods have the potential for increasing power in mediation analysis (Koopman, Howe, Hollenbeck, & Sin, 2015; Yuan & MacKinnon, 2009). This article compares the power of Bayesian credibility intervals for the mediated effect to the power of normal theory, distribution of the product, percentile, and bias-corrected bootstrap confidence intervals at N ≤ 200. Bayesian methods with diffuse priors have power comparable to the distribution of the product and bootstrap methods, and Bayesian methods with informative priors had the most power. Varying degrees of precision of prior distributions were also examined. Increased precision led to greater power only when N ≥ 100 and the effects were small, N < 60 and the effects were large, and N < 200 and the effects were medium. An empirical example from psychology illustrated a Bayesian analysis of the single mediator model from prior selection to interpreting results. 相似文献
8.
Marc Beardsley Judit Martínez Moreno Milica Vujovic Patricia Santos Davinia Hernández-Leo 《British journal of educational technology : journal of the Council for Educational Technology》2020,51(5):1631-1652
Advances in the field of multimodal learning analytics (MMLA) research is often accomplished by actively exploring new technologies and techniques related to the collection and analysis of data. Exploration of ethical principles and procedures for governing the use of new technologies and techniques, however, is not as readily pursued. As collected data grow in complexity and invasiveness, potentially, a growing need is arising to scrutinize ethical aspects of MMLA research. In our study, we introduce an informed consent comprehension test for educational technology research and assess the effects of enhancing MMLA consent forms on comprehension of informed consent and on rates of enrollment in a MMLA study. One form is written from a researcher perspective and the other from a participant perspective. Results of the study involving first-year undergraduate students suggest that the overall level of comprehension did not differ between conditions. Yet, the participant-oriented consent form resulted in significantly lower rates of enrollment. Implications for MMLA researchers are discussed. 相似文献
9.
Studying the effects of pharmacological agents on human endothelium includes the routine use of cell monolayers cultivated in multi-well plates. This configuration fails to recapitulate the complex architecture of vascular networks in vivo and does not capture the relationship between shear stress (i.e. flow) experienced by the cells and dose of the applied pharmacological agents. Microfluidic platforms have been applied extensively to create vascular systems in vitro; however, they rely on bulky external hardware to operate, which hinders the wide application of microfluidic chips by non-microfluidic experts. Here, we have developed a standalone perfusion platform where multiple devices were perfused at a time with a single miniaturized peristaltic pump. Using the platform, multiple micro-vessel networks, that contained three levels of branching structures, were created by culturing endothelial cells within circular micro-channel networks mimicking the geometrical configuration of natural blood vessels. To demonstrate the feasibility of our platform for drug testing and validation assays, a drug induced nitric oxide assay was performed on the engineered micro-vessel network using a panel of vaso-active drugs (acetylcholine, phenylephrine, atorvastatin, and sildenafil), showing both flow and drug dose dependent responses. The interactive effects between flow and drug dose for sildenafil could not be captured by a simple straight rectangular channel coated with endothelial cells, but it was captured in a more physiological branching circular network. A monocyte adhesion assay was also demonstrated with and without stimulation by an inflammatory cytokine, tumor necrosis factor-α. 相似文献
10.
Dario SAMBUNJAK Mirjana HUIĆ Darko HREN Milica KATIĆ Ana MARUŠIĆ Matko MARUŠIĆ 《Learned Publishing》2009,22(1):57-70
Scholarly journals, especially in non‐English‐speaking countries, may perform very different functions depending on whether they are published for national or international audiences. Four hundred and sixty‐six academic physicians and non‐academic general practitioners in Croatia were surveyed on their knowledge about two Croatian medical journals: Lije?ni?ki vjesnik (published in Croatian) and Croatian Medical Journal (published in English). The physicians were also surveyed about the importance of all national and international journals published in Croatia, and the types of articles they thought should be published in these journals. More respondents rated national (n = 329, 72.6%) than international journals (n = 275, 63.5%, P < 0.001, Wilcoxon test) as very important for the medical profession. On the other hand, publishing in international journals was more often rated as important than publishing in national journals (n = 184, 42.5% vs. n = 125, 27.8%; P < 0.001, Wilcoxon test). Guidelines for clinical practice were rated as the most important publication item in national journals, and original scientific articles in international journals. 相似文献