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1.
Sonika Gupta Niraj Shende Swati Banerjee Satish Kumar M. V. R. Reddy Bhaskar C. Harinath 《Indian journal of clinical biochemistry : IJCB》2002,17(1):5-8
Tuberculosis remains major health problem in India and developing countries Immunodiagnosis has important role in screening,
diagnosis and management of tuberculosis. SEVA TB ES-31 antigen has shown potential in detecting tuberculous IgG antibody
in earlier studies from our laboratory. In the present study we have analysedSEVA TB ES-31 antigen specific immunoglobulinsIgM, IgA and IgG in clinically and bacteriologically confirmed pulmonary tuberculosis cases to determine the usefulness of specific immunoglobulin
class in the diagnosis of patients attending the hospital.
Of the 30 cases of pulmonary tuberculosis 25 (83.3%) were positive for IgG, 19 (63.3%) for IgM and 16 (53.3%) for IgA. On
combining IgG and IgM positivity, sensitivity was increased to 93.3%. While combining IgG and IgA positivity, sensitivity
increased to 90%. However specificity was decreased to 66.6% and 70% for both of these combinations respectively. It could
be envisaged from this study that IgG antibody detection against ES-31 antigen showed acceptable sensitivity (83.3%) and specificity
(86.6%) compared to IgM or IgA alone or in combination. When immune responses were analysed according to degree of sputum
positivity, IgG response was observed to be predominant in all grades, compared to IgM or IgA antibody. The addition of IgM
or IgA as an adjunct test increases the sensitivity but at the cost of specificity. Hence the detection of IgG alone is more
useful compared to IgM or IgA assay, in detecting tuberculosis disease cases coming to the hospital. 相似文献
2.
International Guidelines have voted for PCR as the Gold Standard in COVID diagnosis. Nasoparyngeal swab is the preferred specimen for PCR. It has a high probability of diagnosing early infection. But the diagnostic sensitivity of nasopharyngeal PCR decreases with increase in lapse between the infection and presentation to hospital. This might lead to dire consequences of labelling these patients as false negative, though such patients have been proved to be potentially infective since viral shedding occurs through other body fluids (stools) for long. COVID infection reveals that the IgM antibodies start to appear as early as 5th day of infection and switches over to IgA within 2–3 days. The aim of the study was to see if COVID antibody testing be coupled with PCR for diagnosis especially in patients presenting late (more than 14 days) of onset of infection? And if the antibodies are giving values, hence can them be reported quantitatively rather than in qualitative fashion? The second objective was to see if the COVID antibody levels be used to monitor the disease severity? And if the antibody levels of SARS CoV 2 be used an indicator to monitor the recovery? 相似文献
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This paper presents the early investigations about the nature of sound of the Pythagoreans, and how they started a tradition
that remains valid up to present times—the use of numbers in representing natural reality. It will touch on the Pythagorean
notion of musical harmony, which was extended to the notion of universal harmony. How the Pythagorean ideas have inspired
many great works in physics, such as those of Galileo, Kepler and Newton, will also be presented. In exploring the legacy
of Pythagoras to physics and the study of the universe, some valuable insights on the nature of science that can inspire budding
physicists are extracted. 相似文献
5.
提出了一种用于三维电磁场有限元分析的数值技术,即与波阵法配合使用的目标区域定位(TRL)算子.首先对波阵法进行了分析,然后对TRL算子原理进行了详细论述,并讨论了TRL算子在非线性场合应用的可行性,指出其仍能够适用并保持原来的高效率.还介绍了TRL算子在采用矢量磁位函数有限元公式中的实现.最后给出了一个三维静磁场建模的算例,分别采用TRL算子和有限元软件FEMLAB.结果表明:与FEMLAB相比,TRL算子可以节省可观的计算机资源. 相似文献
6.
Satish Nargundkar Milind Shrikhande 《Decision Sciences Journal of Innovative Education》2014,12(1):55-72
Student Evaluations of Instruction (SEIs) from about 6,000 sections over 4 years representing over 100,000 students at the college of business at a large public university are analyzed, to study the impact of noninstructional factors on student ratings. Administrative factors like semester, time of day, location, and instructor attributes like gender and rank are studied. The combined impact of all the noninstructional factors studied is statistically significant. Our study has practical implications for administrators who use SEIs to evaluate faculty performance. SEI scores reflect some inherent biases due to noninstructional factors. Appropriate norming procedures can compensate for such biases, ensuring fair evaluations. 相似文献
7.
Yogesh Sankarasubramaniam Krishnan Ramanathan Subhankar Ghosh 《Information processing & management》2014
Automatic text summarization has been an active field of research for many years. Several approaches have been proposed, ranging from simple position and word-frequency methods, to learning and graph based algorithms. The advent of human-generated knowledge bases like Wikipedia offer a further possibility in text summarization – they can be used to understand the input text in terms of salient concepts from the knowledge base. In this paper, we study a novel approach that leverages Wikipedia in conjunction with graph-based ranking. Our approach is to first construct a bipartite sentence–concept graph, and then rank the input sentences using iterative updates on this graph. We consider several models for the bipartite graph, and derive convergence properties under each model. Then, we take up personalized and query-focused summarization, where the sentence ranks additionally depend on user interests and queries, respectively. Finally, we present a Wikipedia-based multi-document summarization algorithm. An important feature of the proposed algorithms is that they enable real-time incremental summarization – users can first view an initial summary, and then request additional content if interested. We evaluate the performance of our proposed summarizer using the ROUGE metric, and the results show that leveraging Wikipedia can significantly improve summary quality. We also present results from a user study, which suggests that using incremental summarization can help in better understanding news articles. 相似文献
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E-mail-alerting system of online databases is a new trend catching up fast with researchers. Results of auto-run set queries are informed through e-mails as ‘alerts’ to the registered user. Even though e-mail-alerting systems are quite popular amongst Internet users, their inherent advantages remain unexplored in the Indian scenario. An effort to explore all such features available in the ScienceDirect online database has been made in this paper. The process of registration for activating e-mail alerts, customizing a home page, selecting favorite journals, search alerts, journal issue alerts, citation alerts and search history are briefed with screen shot examples. The study emphasizes the fact that librarians and information Science professionals should take lead roles in unveiling all such possible features available in various online databases. They should also make efforts at informing the user community of the utility of such features in a bid to enhance the research output. 相似文献
9.
Sankaran Ramanathan 《亚洲交流杂志》2013,23(2):65-91
This article synthesizes the findings of two empirical surveys carried out in 1986 and 1990 in Malaysia. It also presents a brief historical background of the political process in the country, as well as an overview of the Malaysian media. Finally, it touches on the latest general elections in Malaysia, held in 1995, and their implications. 相似文献
10.
Harvey J. Brightman Satish Nargundkar 《Decision Sciences Journal of Innovative Education》2013,11(4):297-304
The advent of digital course offerings, the use of social media, the integration of the Khan Academy into curricula, the use of smart phones and tablets, and massive online courses place greater emphasis than ever on effective teaching. While business schools fund faculty development in teaching, too few doctoral programs offer systematic teacher training. We discuss the lack of, and the need for, comprehensive teacher‐training programs. We present the Robinson College of Business model and offer recommendations on how to get started. It is time for PhD programs to certify that their students are capable of teaching upon graduation. 相似文献