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BackgroundOne-hour postprandial hyperglycemia is associated with increased risk of type 2 diabetes and cardiovascular disease. Physical activity (PA) has short-term beneficial effects on post-meal glucose response. This study compared the oral glucose tolerance test results of 3 groups of people with habitually different levels of PA.MethodsThirty-one adults without diabetes (age 25.9 ± 6.6 years; body mass index 23.8 ± 3.8 kg/m2; mean ± SD) were recruited and divided into 3 groups based on self-reported PA volume and intensity: low activity < 30 min/day of moderate-intensity activity (n = 11), moderately active ≥ 30 min/day of moderate-intensity PA (n = 10), and very active ≥ 60 min/day of PA at high intensity (n = 10). Participants completed an oral glucose tolerance test (50 g glucose) with capillary blood samples obtained at baseline, 15 min, 30 min, 45 min, 60 min, 90 min, and 120 min post-ingestion.ResultsThere were no significant differences between groups for age or body fat percentage or glycated hemoglobin (p > 0.05). The groups were significantly different in terms of baseline glucose level (p = 0.003) and, marginally, for gender (p = 0.053) and BMI (p = 0.050). There was a statistically significant effect of PA on the 1-h postprandial glucose results (p = 0.029), with differences between very active and low activity groups (p = 0.008) but not between the moderately active and low activity groups (p = 0.360), even when baseline glucose level and gender differences were accounted for. For incremental area under the curve there was no significant effect of activity group once gender and body fat percentage had been accounted for (p = 0.401). Those in the low activity group took 15 min longer to reach peak glucose level than those in the very active group (p = 0.012).ConclusionThe results suggest that high levels of PA have a beneficial effect on postprandial blood glucose profiles when compared to low and moderate levels of activity.  相似文献   
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Morris Teubal 《Research Policy》1997,25(8):1161-1188
This paper presents an evolutionary framework for horizontal technology policies (HTPs) especially market-friendly ones involving project-based incentives (e.g. R&D project based grants rather than tax-based incentives to yearly expenditures on R&D). HTPs are a category of technological policies whose objective is to promote technological development per se, and associated management and organizational routines, irrespective of industrial branch or technological area. They are being increasingly adopted by both advanced countries and newly industrialized countries in response to the new opportunities and threats opened up by the technological revolution and by the processes of liberalization and globalization; and they complement the more specific and well-known selective and vertical policies aimed at individual sectors and technologies. The analysis is conducted within a learning-to-innovate framework with emphasis on collective, organizational learning; search; and market-building. The outcome is a technology policy cycle with distinct infant, growth, and mature phases. Proactive ‘generation’ of a critical mass of projects for efficient learning and diffusion of innovation routines becomes the aim of the infant phase; while the mature phase of the policy should focus on policy restructuring including drastic reductions in the support of routi projects and enhanced support of more complex types of innovation. The paper also emphasizes the importance of a neutrality component in incentives in the infant phase of increasing selectivity; and of building policy capabilities for efficient policy design and implementation.  相似文献   
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This introductory essay reviews the key contributions of David Teece's landmark paper “Profiting from Innovation” published in research policy in 1986. It summarises the contributions of each of the papers in the special issue. It then offers some perspectives on the key themes emerging from these papers, and on the broader challenges facing researchers, strategists and policymakers in the field of technology innovation today.  相似文献   
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Toys can be used to promote children's cognitive, physical, motor, language, social, and emotional development. Safety and developmental appropriateness are of the utmost importance when selecting children's toys. Parents and teachers and other helping professionals need to teach children the safe use of toys to prevent toy-related accidents. Obtain additional information regarding toy safety by calling the U.S. Consumer Product Safety Commission at 1(800)638-CPSC.  相似文献   
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当前教育信息化蓬勃发展,在备受赞赏的同时也屡被质疑。至于原因,恐怕还是“人究竟是怎么学习的,怎样才能促进有效学习?”这一根本性问题依然未得到彻底解决。该文从教育信息化的发展现状谈起,剖析目前存在的问题及解决方法,然后仔细梳理了学习科学的发生、发展和研究现状,指出脑科学与学习、基于大数据的学习分析和技术增强的学习等学习科学研究将有助于推动教育从更深的层面发生变革。  相似文献   
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Over a decade after Napster’s introduction, file sharing programs still shoulder much of the blame for music and other media’s declining sales. Although labels and industry associations point their fingers at the harm digital piracy and file-sharing cause, they are less likely to admit the extent to which these anti-markets inform everyday decisions. File-sharing technologies create networks of users that serve as profitable data for ratings and metrics agencies. Using a case study of BigChampagne and its relationship to Napster, this article considers how the look, structure, and function of file-sharing software helped turn an economically threatening community into a commodity and how piracy’s disruptive potential is always in tension with processes of commodification.  相似文献   
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