Carnosine in health and disease     

Guilherme Giannini Artioli  Craig Sale  Rebecca Louise Jones 《European Journal of Sport Science》2019,19(1):30-39

Abstract

Carnosine was originally discovered in skeletal muscle, where it exists in larger amounts than in other tissues. The majority of research into the physiological roles of carnosine have been conducted on skeletal muscle. Given this and the potential for muscle carnosine content to be increased with supplementation, there is now a large body of research examining the ergogenic effects (or otherwise) of carnosine. More recent research, however, points towards a potential for carnosine to exert a wider range of physiological effects in other tissues, including the brain, heart, pancreas, kidney and cancer cells. Taken together, this is suggestive of a potential for carnosine to have therapeutic benefits in health and disease, although this is by no means without complication. Herein, we will provide a review of the current literature relating to the potential therapeutic effects of carnosine in health and disease.  相似文献   

多自由度刚性杆系静平衡计算     

沈健  董达善 《上海海事大学学报》2003,24(2):146-149

介绍了多自由度刚性杆系静平衡的分析计算。通过调整初始设计中杆件的长度来优化系统。这对于大型起重机前大梁拉杆系统以及一些相关系统的设计优化有一定的实际参考及应用价值  相似文献   

对第一次世界大战时意大利中立问题的认识     

孙银钢  董大学 《首都师范大学学报(社会科学版)》2005,(Z1)

第一次世界大战时,意大利发表中立宣言,中立选择有其深刻原因:战前意大利同其两个最为重要的劲敌法奥之间的关系发生根本性转变,意法关系由高度紧张走向缓和并趋于稳定,而意奥之间暂时冷却的深刻矛盾渐渐暴露出来,意奥关系至战前已相当紧张;焦利蒂时代的“平衡政策”是中立选择的依据。战时意大利政府决策的转变,新政府期望通过战争谋求强国身份和分享战争果实,将意大利带入其难以负担的世界大战。  相似文献   

湖南省田径队男子三级跳远成功的启示     

谢朝辉  熊卫  钟大鹏 《湖北体育科技》2003,22(1):93-94,96

通过湖北省田径队优秀男子三级跳远运动员熊卫在湖南省田径队男子三级跳远组训练过程的分析，认为教练员科学的、极具鲜明特点的训练方法，以及与运动员团结协作，努力拼搏，无私奉献的敬业精神，是湖南省男子三级跳远取得成功的关键。  相似文献   

江泽民舆论监督思想初探   总被引：1，自引：1，他引：0  

田大宪 《陕西师范大学学报(哲学社会科学版)》2002,31(1):66-73

江泽民舆论监督思想是马克思主义新闻观的继承和发展。江泽民“三个代表”重要思想是舆论监督的总纲。党和人民的根本利益是舆论监督的出发点和归宿 ;正确的舆论导向是舆论监督的前提 ;遵循新闻规律是舆论监督的依据 ;发挥监督系统的整体合力是舆论监督的有效途径  相似文献   

青少年足球运动员的速度力量训练     

杨大强 《体育成人教育学刊》2002,18(3):84-85

速度力量是速度与力量的综合表现 ,它的提高受速度素质与力量素质的牵制。力量和速度是青少年足球运动员快速能力的决定因素。速度力量的典型表现形式是爆发力、起动力、反应力。提出青少年足球运动员力量素质发展的敏感期与必要性 ,对速度力量的理论与实践作了概述。  相似文献   

Mediating the Economic Pulses: The International Connection in Portuguese Higher Education     

Pedro Teixeira  Alberto Amaral  Maria João Rosa 《Higher Education Quarterly》2003,57(2):181-203

Portugal, as a small and increasingly integrated European economy, has been influenced by some of the major trends that defined the agenda of higher education policy in recent decades. Its backwardness – notably in terms of skills, education, and training – has frequently prompted a focus of attention on its international counterparts, particularly those in Europe, in search of affinities, solutions and errors to avoid. The search for guidance has also created an opportunity for the intervention of international organisations. Until Portugal joined the European Union (EU) in 1986, the Organisation for Economic Cooperation and Development (OECD) and the World Bank were the main agencies playing this role. Henceforth, those institutions lost some influence, and the European dimension gained increasing prominence. This article discusses the role of those international organisations in the definition of priorities for Portuguese higher education policy in recent decades, and provides a general overview of the outside perceptions of the Portuguese situation as understood by these international organisations. In particular, the article focuses on those interventions that promoted the influence of market mechanisms in the Portuguese higher education system by emphasising the need for higher education institutions (HEIs) to strive for increased economic responsiveness.  相似文献   

视频元数据全文检索系统的研究与实现   总被引：3，自引：0，他引：3  

陈玮  陆达 《情报学报》2004,23(1):32-35

本文阐述了采用XML文档按照MPEG 7标准描述视频数据的趋势 ,研究了适合于半结构化视频描述的全文检索索引结构。该索引保存了文档中的结构信息 ,从而可以对视频数据进行全方位多层次的查询。提出了一些缩减索引空间的策略和算法。  相似文献   

UNIMARC Format Relevance: Maintenance or Replacement?     

Rosa Maria Galvão 《Cataloging & classification quarterly》2018,56(1):62-82

This article presents an empirical study focused on a qualitative analysis of the UNIMARC format. An analysis of the structural quality of the data provided by the format is evaluated to determine its current suitability for meeting the requirements and trends in data architecture for the information network and the Semantic Web. Driven by a set of quality characteristics that identify weaknesses in the data schema that cannot be bridged by simply converting data to MARC XML or RDF/XML, we conclude that the UNIMARC format is not compliant with the current metadata schema desiderata and must be replaced.  相似文献   

EFFECTS OF TEACHER–STUDENT RELATIONSHIPS ON PEER HARASSMENT: A MULTILEVEL STUDY     

Beatriz Lucas‐Molina  Ariel A. Williamson  Rosa Pulido  Alicia Prez‐Albniz 《Psychology in the schools》2015,52(3):298-315

Peer harassment is a major social problem affecting children and adolescents internationally. Much research has focused on student‐to‐student harassment from either an individual or a multilevel perspective. There is a paucity of multilevel research on students’ relationships with the classroom teacher. The purpose of this study was to use a socioecological perspective to examine the relationships between individual student‐level characteristics, problematic teacher–student relationships, and student‐reported peer harassment. A total of 1,864 children (50.7% female) aged 8 to 13 years (M = 9.82, SD = 1.24), nested in 27 schools (58.2% public) in Spain, participated in the study. Ninety‐four homeroom teachers reported on teacher–student relationships, and students completed self‐report measures related to peer harassment and teacher–student relationships. Multilevel models showed that relationships between students and teachers exerted a varying degree of influence on classroom levels of peer harassment. Specifically, student‐reported teacher support was associated with diminished student‐reported peer victimization, whereas direct and indirect student‐reported teacher‐to‐student aggression was associated with increased peer victimization. Additionally, student‐reported student‐to‐teacher aggression and teacher‐to‐student aggression were associated with increased student‐reported peer aggression. Teacher‐reported variables at the classroom level, however, contributed little to student‐reported outcomes. Results are discussed in the context of future research on relationships between teachers and students.  相似文献