Potential Effect of <Emphasis Type="Italic">Bacopa monnieri</Emphasis> on Nitrobenzene Induced Liver Damage in Rats     

Menon BR  Rathi MA  Thirumoorthi L  Gopalakrishnan VK 《Indian journal of clinical biochemistry : IJCB》2010,25(4):401-404

The study was designed to evaluate the hepatoprotective activity of ethanolic extract of Bacopa monnieri in acute experimental liver injury induced by Nitrobenzene in rats. The extract at the dose of 200 mg/kg body weight was administered orally once every day for 10 days. The increased serum marker enzymes, Aspartate transaminase, Alanine transaminase and alkaline phosphatase were restored towards normalization significantly by the extract. Significant increase in SOD, CAT and GPx was observed in extract treated liver injured experimental rats. Histopathological examination of the liver tissues supported the hepatoprotection. It is concluded that the ethanolic extract of Bacopa monieri plant possess good hepatoprotective activity.  相似文献   

人称代词的虚化及其语法化解释     

曾卫军 《湖南城市学院学报》2007,28(2):81-83

人称代词“你”、“他”的虚化可按其虚化程度分为三类:“你”、“他”的活用;“你”、“他”的虚指和“他”成为指称标记。这实际上是一个由实词到虚词再到只有语用功能的附着形式的语法化过程。它遵循语法化的渐变性、单向性、并存性原则,体现了现代汉语口语中人称代词发展的趋向。  相似文献   

Word-Decoding Deficits in Norwegian: The Impact of Psycholinguistic Marker Effects     

T. Nergård-Nilssen 《Reading and writing》2006,19(3):265-290

The effects of regularity, frequency, lexicality, and granularity on single word reading in Norwegian children with dyslexia and control children matched for age and reading level were examined. The reading impaired children showed the same pattern of performance as younger children matched for reading level on most tasks except for the fact that they worse at nonword reading. The findings are discussed against different theoretical models of reading.  相似文献   

金融监管法制化试析     

陈金威 《黔南民族师范学院学报》2002,22(1):51-55

针对当前世界经济和金融大势，紧密结合亚洲金融危机和中国金融体制改革的现状，金融监管法制化已被提升到确立、完善和保障金融监管制度平稳、有效运行，促进经济金融协调发展的重要地位。现阶段我国金融监管法制化的主旨宜为促进竞争、加强调控、保障安全。各国金融法律制度一般从市场准入、业务经营、市场退出三方面加以规范和调节，并着力避免两种不应有的趋向。最后对金融监管法制化的国际进程作了分析展望。  相似文献   

"是"标记一般主语位置上的施事性对比焦点的限制条件     

张道俊 《海南师范大学学报(社会科学版)》2007,20(1):116-121

在肯定性陈述结构中,一般主语位置上的施事成为对比焦点且受“是”标记是有一些限制条件的。如果焦点标记词“是”与范围副词“都/就”都针对某个施事,则“是”与“都/就”只能分现,不能同现,因为一个施事只能允许被凸显或强调“量性”和“施者”这两个信息成分中的一个。对比焦点标记词“是”与“连”在同一句子里不能共现,其原因在于违背了“单一强式焦点原则”。在变式句中,一般主语位置上的施事(话题)都不能接受“是”的标记而成为对比焦点,因为话题与焦点在本质上是对立的。  相似文献   

Diagnostic and prognostic value of the urinary excretion of beta-aminoisobutyric acid in patients with urinary bladder cancer     

R. L. Gupta  K. Ramachandran  Monika  J. S. Chowhan 《Indian journal of clinical biochemistry : IJCB》1996,11(1):59-61

Urinary excretion of beta-aminoisobutyric acid (BAIB), was determined in 28 active and 12 inactive bladder cancer patients. Mean excretion of BAIB was higher in active cancer patients-187.8 mg/24 hours whereas it was 120.4 mg/24 hours in inactive cancer patients. The increased BAIB excretion in both disease groups was independent of tumour stage. BAIB appears to be a useful diagnositic aid in the assessment of bladder cancer patients.  相似文献   

Application of tumor markers in ovarian malignancies     

T. Malati  G. Rajani Kumari  B. Yadagiri 《Indian journal of clinical biochemistry : IJCB》2001,16(2):224-233

Ovarian cancer is the fifth leading cause of death in women. The incidence of this malignancy increases in women over the age of 40. The overall five years survival is less than 30%, as most women present with advanced stage disease. Until recently, detection of early stage ovarian cancer has been difficult since it is usually nonpalpable and asymptomatic. The definitive diagnosis of an ovarian mass is a common problem in gynecologic patients with adnexal mass. The routine standard evaluation for adnexal masses includes patient's history, physical examination, ultrasound and histopathological examination. These parameters individually or in combination have little predictive value. The accuracy of diagnostic tools are of immense value and great concern to practicsing Gynecologists and Oncologists. The clinical application of serum concentration of CA 125, AFP and hCG is of great help not only as diagnostic aid but also in monitoring efficacy of any treatment modality like chemotherapy, radiotherapy or surgical resection. Additionally, evaluation of tumor marker concentration helps in predicting early biochemical recurrence and in prognostication in different types of ovarian malignancies. The ability to differentiate a malignant mass from a benign pelvic mass pretherapeutically could be enhanced optimally by additional use of tumor markers such as cancer antigen CA-125, alphafetoprotein and human chorionic gonadotrophin in pre-and postmenopausal women.  相似文献   

BMD and Serum Intact Osteocalcin in Postmenopausal Osteoporosis Women     

Jagtap VR  Ganu JV  Nagane NS 《Indian journal of clinical biochemistry : IJCB》2011,26(1):70-73

India seems to have the highest prevalence of osteoporosis. With growing awareness of osteoporosis and its impact on life span especially in India, special attention is being paid to early detection, management and treatment of postmenopausal osteoporosis in women. Measurement of BMD and osteocalcin are of value in estimating bone turnover rates. The aim of this study is (1) to measure the specific, sensitive bone formation marker such as osteocalcin and BMD in postmenopausal osteoporosis women and postmenopausal non-osteoporosis women; (2) the follow up study to evaluate the impact of specific antiresorptive therapy (alendronate + calcium + vitamin D) regimen in postmenopausal osteoporosis by assaying osteocalcin and BMD. Sixty clinically diagnosed postmenopausal osteoporosis patients and 60 normal subjects (postmenopausal non-osteoporosis women) were recruited as control. Mean bone mineral density T score and Z score was significantly decreased (P < 0.001) in postmenopausal osteoporosis patients as compared to controls. Highly significant increase in the mean score of BMD—T score and Z score from baseline to post therapy of 3 months was observed in postmenopausal osteoporosis women. Serum osteocalcin levels were significantly increased (P < 0.001) as compared to control group. Serum osteocalcin levels were decreased significantly (P < 0.001) from baseline to post therapy of 3 months in postmenopausal osteoporosis women. BMD is the best quantifiable predictor of osteoporotic fracture and osteocalcin is specific, sensitive, promising, currently used marker for better prognosis of osteoporosis and for monitoring responses to antiresorptive therapy.  相似文献   

Effect of arogh—A polyherbal formulation on the marker enzymes in isoproterenol induced myocardial injury     

S. Suchalatha  C. S. Shyamala Devi 《Indian journal of clinical biochemistry : IJCB》2004,19(2):184-189

To study the protective role of Arogh on isoproterenol induced myocardial damage in rats. The effect of Arogh pretreatment on isoproterenol induced myocardial damage was assessed by studying the levels of lipid peroxides and changes in the activity of marker enzymes such as creatine kinase, lactate dehydrogenase and transaminases in serum and heart tissue. In isoproterenol administered rats, a significant decrease was observed in the activity of marker enzymes in the heart with a corresponding increase in their levels in serum. Lipid peroxide levels increased significantly in the serum and heart. In rats pretreated with arogh, the level of lipid peroxides and the activity of marker enzymes were maintained at near normal values. Pretreatment with Arogh offered a protective effect against isoproterenol induced myocardial damage in rats as evidenced by LDH isoenzyme patterm and histopathological studies of heart tissue.  相似文献   

谈话语体中“你比如说”的话语功能探析     

邓瑶 《云南师范大学学报(教育科学版)》2011,(4):63-67

谈话语体中语用标记＂你比如说＂具有语篇组织功能和交际互动功能。其语篇组织功能主要由＂比如说＂来实现,首先体现为用作举例标记,后来发展为两个方向：第一,举例标记兼话题标记;第二,假设标记。其交际互动功能主要由＂你＂来承担。＂你比如说＂是谈话中发话者采取两种积极的言语策略而形成的话语功能的组合,是谈话语体中一个凝固化的习语。  相似文献