共查询到20条相似文献，搜索用时 250 毫秒
1.
雌激素(estrogen,E)是维持女性第二性征最主要的甾体物质,其在神经系统也发挥广泛的药理作用,如抗脑缺血再灌注损伤减少梗死面积,抗自由基形成,调节兴奋性氨基酸释放等.雌激素自身作为一种抗氧化剂能够通过调节体内氧化还原平衡发挥神经保护作用.另外,雌激素在神经系统药理作用的发挥与其受体密不可分,经典的雌激素受体(estrogen receptor, ER)主要位于细胞核内,包括ER-α和ER-β两种亚型,二者均可在大脑皮质和海马表达:卵巢切除大鼠学习记忆能力降低的同时,ER-α在大脑皮质区和海马区表达也显著减少;ER-β基因敲除能够严重影响学习记忆行为、长时程增强(long term potentiation,LTP)和突触强度,该受体可能参与了高级脑功能的调节.N-甲基-D-天冬氨酸(N-methyl-D-aspartic acid,NMDA)受体作为与学习记忆密切相关的受体,与雌激素受体在海马区存在共表达.雌激素可能通过膜相关的雌激素受体快速激活ERK1/2信号转导通路,进一步诱导NMDA受体NR2B亚基磷酸化,激活NMDA受体,三者均会影响突触可塑性.本文就雌激素及其受体和Glu-NMDA受体通路与学习记忆的相关性进行综述. 相似文献
2.
3.
4.
5.
目的:探讨2型糖尿病病人内脏型肥胖和血管并发症的关系.方法:采用CT影像学检查方法对50例2型糖尿病病人进行内脏脂肪测定,根据有无内脏型肥胖将病人分为内脏肥胖组和非内脏肥胖组,观察两组血管并发症危险因子情况(血压、血脂).结果:内脏肥胖组的内脏脂肪平均值为127.12cm,非内脏肥胖组为7O.21cm;内脏肥胖组比非肥胖型组有更高的甘油三酯、血压(P<0.01).结论:内脏脂肪肥胖和心血管危险因子密切相关,是引起2型糖尿病血管并发症的重要危险因素. 相似文献
6.
婴儿期是个体情绪调节发展的起点,也是最关键的时期之一.看护者对婴儿的情绪调节发展有着重要影响,各个理论模型从不同角度阐述了看护者在婴儿情绪调节发展中的作用及其机制:依恋系统激活和动力模型强调看护者的可得性对婴儿情绪调节的影响,自我决定理论强调看护者的敏感性对婴儿情绪调节的影响,社会学习理论强调看护者的回应策略对婴儿情绪调节的影响,共同调节模型理论强调看护者的依随行为对婴儿情绪调节的影响.文章着重梳理了四大理论模型,并提出了未来研究应进一步探讨的问题. 相似文献
7.
高中生物教材"生命活动的调节"部分介绍了与人类乳腺的生长发育有关的雌激素、孕激素和催乳素,但对它们之间的关系及其在乳腺的生长发育中的作用却没有涉及.下面主要介绍的是直接影响人类乳腺的生长发育和各种生理功能的三种激素及其相互之间的关系,同时也介绍了与乳腺发育间接有关的人体内各种内分泌激素. 相似文献
8.
论运动时人体生理功能活动的整体性 总被引：1，自引：0，他引：1
董静梅 《西北成人教育学报》2005,(1):47-49
本文从系统学原理和控制论的观点出发,以运动生理学、生化学为基础,论述了运动时人体各肌群之间、肌痤活动与内脏活动以及各系统之间的协调配合在内分泌系统的调节和神经系统的整和控制下,以运动系统为主体性活动。 相似文献
9.
采用内隐联结测验(IAT)、情绪调节自我效能感量表和网络道德敏感性问卷对河南省某高校50名学生进行施测,使用SPSS进行统计分析,以研究大学生内隐网络利他行为倾向及其与情绪调节自我效能感、网络道德敏感性的关系。结果显示,网络利他行为存在显著的IAT效应,表明网络利他行为具有内隐倾向;内隐网络利他倾向高分组与低分组的得分差异显著;网络利他行为内隐倾向在性别变量上没有出现显著差异,文理科生内隐网络利他倾向差异显著;内隐网络利他倾向与情绪调节自我效能感及网络道德敏感性相关不显著;IAT可以作为测量网络利他行为内隐倾向的有效工具。 相似文献
10.
ATP敏感性钾通道是一种受细胞内ATP浓度,NDPs,KCOs,SUs等多种因素调节启闭的钾通道.在生理状态下,KATP处于关闭状态;在缺血、缺氧等病理状态下KATP通道则激活开放,并通过改变细胞兴奋性,影响细胞功能而发挥重要的调节作用. 相似文献
11.
邱崇丙 《唐山师范学院学报》2014,(1):21-23
汉字的六书,《说文》对“转注”一类,语焉不详。后世学者提及转注,也仅限于许慎所举出的例字。《汉字例说》一文,作者从转注的角度综合考虑,对部分现代常用字作了分析,跟传统的解释有所不同。希望能抛砖引玉,互相切磋,以推进学术研究。 相似文献
12.
13.
14.
《海外英语》2007,(5):10-11
Many college freshmen arrive woefully unprepared to do college work, and as disadvantaged populations continue to grow, the share of the American work force that has made it through college is expected to plummet. Many experts blame that educational failure not just on high schools but also on colleges. School & College, a special report by The Chronicle, looks at efforts to fix the system. What reforms would better prepare students for college? What should schools and colleges be doing differently? How should state and federal officials help? 相似文献
15.
Rachel Zupek 《海外英语》2007,(11):40-41
我们绝大部分人都同意一件事情——我们喜欢金钱。但是你对金钱的喜欢之情足够到让你创立一份事业么?.财富通常被人忽视,主要在于人们不能真正了 相似文献
16.
YANGShiguo 《重庆大学学报(英文版)》2004,3(1):86-88
The problem on the geometrc inequalities involving an n-dimensional simplex and its inscribed simplex is studied. Aninequality is established, which reveals that the difference between the squared circumradius of the n-dimensional simplex andthe squared distance between its circumcenter and barycenter times the squared circumradius of its inscribed simplex is not lessthan the 2(n-1)th power of n times its squared inradius, and is equal to when the simplex is regular and its inscribed siplex is atangent point one. Deduction from this inequality reaches a generalization of n-dimensional Euler inequality indicating that thecircumradius of the simplex is not less than the n-fold inradius. Another inequality is derived to present the relationship betweenthe circumradius of the n-dimensional simplex and the circumradius and inradius of its pedal simplex. 相似文献
17.
《海外英语》2007,(4):36
There are numbers of crossroads on our long and unpredictable life journey where we totally have no idea about which direction to choose. No matter what our decision is, we should not turn back, but face the music and go ahead instead. I am this kind of girl who always does try without regretting, one example is how I dealt with my love. 相似文献
18.
Migration occurs behind a variety of reasons and has a great effect on the whole world. People may migrate in order to improve their economic situation, or in order to escape civil strife, persecution, and environmental disasters. The impact of migration is complex, bringing both benefits anddisadvantages. This paper briefly talks about the causes of migration, the allocation of benefits, and the ways in which individual countries and the international community deal with this important subject. 相似文献
19.
20.
GUO Bao-feng Xiao Da-wei 《重庆大学学报(英文版)》2005,4(3):129-133
Using virtual reality for interactive design gives a designer an intuitive vision of a design and allows the designer to achieve a viable, optimal solution in a timely manner. The article discusses the process of making the Virtual Reality System of the Humble Administrator＇s Garden. Translating building data to the Virtual Reality Modeling Language （VRML） is by far unsatisfactory. This creates a challenge for computer designers to do optimization to meet requirements. Five different approaches to optimize models have been presented in this paper. The other methods are to optimize VRML and to reduce the file size. This is done by keeping polygon counts to a minimum and by applying such techniques as object culling and level-ofdetail switching. 相似文献