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1.
潘科 《襄樊职业技术学院学报》2014,(3):51-52
目的 总结高血压患者在全身麻醉下手术期间的麻醉及相关处理方法.方法 选择2012年襄阳职业技术学院附属医院平诊全麻手术（均为高血压患者）25例,对患者在手术期间的麻醉处理及使用相关药物后血流动力学变化进行分析.结果 其中5例患者在全麻术中血压大致正常,与基础血压相比波动在20％以内,未做特殊处理;另外20例患者全麻术中血压升高,用药（硝酸甘油、乌拉地尔）控制后降至正常或接近全麻前水平.25例高血压患者全部未出现心、脑、肾重要脏器并发症.结论 全身麻醉下行各类手术的高血压患者只要麻醉管理得当,适度控制血压,就能安全平稳渡过手术期. 相似文献
2.
目的：探讨血管内皮生长因子（VEGF）在膀胱移行细胞癌中的表达及临床意义。方法：采用免疫组化、ELISA方法对45例膀胱移行细胞癌组织、血浆和10例正常膀胱黏膜组织、30例正常成人血浆中VEGF进行检测分析。结果：VEGF在膀胱移行细胞癌患者中呈高表达，且随分期、分级的增高而增高；膀胱癌手术前患者血浆中VEGF的浓度高于手术后。结论：1．VEGF的表达与膀胱移行细胞癌的病理分级、临床分期及生物学行为有密切关系；2．血浆中VEGF水平可有助于预测膀胱癌患者手术疗效。 相似文献
3.
Xiao-jing Zhao Zhuo Pen Ping Li Er-xiu Chen Jian Liu Yan-xia Gao Yun-xia Ren Li-jun Li 《Journal of Zhejiang University. Science. B》2013,14(6):505-510
Objective
We investigated the influence of β-receptor blocker metoprolol on return of spontaneous circulation (ROSC) during cardiopulmonary resuscitation (CPR) in rats with induced myocardial infarction (MI).Methods
Male Sprague-Dawley rats were randomly divided into three groups: the sham-operated group, the MI group without metoprolol, which was fed the vehicle, and the MI+metoprolol group receiving intragastric metoprolol. Each group was further divided randomly into three subgroups, depending on the dosage of epinephrine administered during subsequent CPR applied after the induction of asphyxial cardiac arrest.Results
The ROSC rate was significantly decreased in the low dose subgroup of MI group, unchanged in the medium dose subgroup of MI group, and significantly decreased in the high dose subgroup of MI group, compared with the same dose subgroup of sham-operated group. MI+metoprolol group had a lower ROSC rate than MI group in the medium dose subgroup, and a higher ROSC rate than MI group in the high dose subgroup. There was no difference in blood K+ values of successful rats between MI group and MI+metoprolol group. The rats with successful CPR had lower blood K+ values than rats with unsuccessful CPR in each of the three treatment groups.Conclusions
Metoprolol administered to MI rats over a long period significantly improved ROSC rates under an appropriate dose of epinephrine during CPR. An increasing high blood K+ value would attenuate the rate of a successful CPR. 相似文献4.
AMI患者PCI术对血浆BNP水平变化的初步临床观察 总被引：1，自引：0，他引：1
目的:观察PCI术对AMI患者血浆中BNP的水平变化,初步探讨PCI对AMI患者预后的影响.方法:采用快速荧光免疫测定法对20例AMI患者PCI治疗前后和20例对照组血浆BNP水平进行检测.结果:AMI患者血浆BNP在AMI患者PCI术与对照组比较有显著性差异(P＜0.05),PCI治疗后呈明显下降趋势.结论:AMI患者PCI治疗血浆BNP水平变化说明PCI术能对改善AMI患者的预后有重要意义. 相似文献
5.
目的:探讨门脉高压症门奇静脉断流失败的原因及防治措施.方法:回顾分析1995.1～2003.2月65例肝硬化门脉高压症患者,行门奇静脉断流术后,5例发生消化道再出血.结果:65例患者再出血发生率7.7%(5/65).1例胃底静脉曲张破裂出血;2例胃黏膜广泛充血、糜烂、渗血;2例出血与胃及食道无关.结论:术中规范操作,术后综合治疗可有效防止术后再出血. 相似文献
6.
Balachandar V Lakshman Kumar B Sasikala K Manikantan P Sangeetha R Mohana Devi S 《Journal of Zhejiang University. Science. B》2007,8(9):638-646
The aim of the present investigation was to study the major chromosomal aberrations （CA） like deletion, translocation, inversion and mosaic in prostate cancer patients of Tamilnadu, Southern India. Totally 45 blood samples were collected from various hospitals in Tamilnadu, Southern India. Equal numbers of normal healthy subjects were chosen after signing a consent form. Volunteers provided blood samples （5 ml） to establish leukocyte cultures. Cytogenetic studies were performed by using Giemsaanding technique and finally the results were ensured by spectral karyotyping （SKY） technique. In the present investigation, major CA like deletion, translocation, inversion and mosaic were identifed in experimental subjects. Results showed frequent CA in chromosomes 1, 3, 5, 6, 7, 9, 13, 16, 18 and X. In comparison with experimental subjects, the control subjects exhibited very low levels of major CA （P〈0.05）. In the present study, the high frequency of centromeric rearrangements indicates a potential role for mitotic irregularities associated with the centromere in prostate cancer tumorigenesis. Identification of chromosome alterations may be helpful in understanding the molecular basis of the disease in better manner. 相似文献
7.
研究内镜黏膜下剥离术(ESD)治疗早期食管癌及食管癌前病变的治疗价值。对25例早期食管癌及食管癌前病变在确定病变范围及浸润深度后行黏膜下剥离术。先超声内镜判断浸润深度及利用Lugol液染色确定病灶范围,后采用术中标记、粘膜下注射、边缘粘膜切开、剥离及创面处理等方法。结果显示,病灶完整切除,术中无穿孔、出血;术后3、6、12月常规随访,均无复发。1例术后3个月出现食管狭窄,给予扩张后狭窄缓解。结果表明,对早期食管癌及食管癌前病变,内镜黏膜下剥离术是一种安全的内镜下治疗方法。 相似文献
8.
Joe Ayres Tanichya K. Wongprasert John Silva Traci Story Chia‐Fang Sandy Hsu Darshan Sawant D. 《Communication quarterly》2013,61(2):160-171
Two studies were undertaken to assess the value of exposing people to performance visualization in order to help them cope with communication apprehension (CA) in employment interviews. The first study, which took place in a laboratory, employed a pre/post‐test experimental design. Seniors who were preparing to enter the job market took part in mock interviews, completed a state communication apprehension (CA) measure, a trait CA measure, and a scale designed to measure negative thinking. Participants were then assigned to performance visualization, placebo, or control conditions. After exposure to the requisite treatment, they participated in another mock interview and completed the same battery of measures. The second study took place in the field. In this study, participants, who were about to undergo a screening interview for a job, completed state and trait CA measures, were exposed to performance visualization, and completed the state and trait CA measures the second time. These studies indicated that exposure to performance visualization related negatively to CA and negative thoughts, as well as positively to being offered a job. It showed no relationship to being asked back for a second interview. The implications of these findings are discussed in the conclusion of this report. 相似文献
9.
川崎病合并支原体感染14例诊治体会 总被引：1，自引：0，他引：1
目的探讨小儿川崎病合并支原体感染的临床特征及诊治体会。方法对临床诊断为川崎病合并支原体感染的患儿进行回顾性分析。结果 14例患儿均有发热;球结合膜充血13例,皮疹8例,口腔粘膜改变14例,手足硬性水肿、指（趾）脱皮14例,颈部淋巴结肿大12例,卡痕、肛周粘膜潮红5例。白细胞增高、血C R P增高9例,心脏彩超示冠状动脉病变（C AL）2例。所有患儿均用阿奇霉素序贯治疗,并早期大剂量人血丙种球蛋白（IVIG）及阿司匹林、潘生丁治疗,13例治愈,1例呈IVIG不反应,再次予以IVIG后痊愈。结论肺炎支原体可能参与川崎病的发病。 相似文献
10.
目的:分析检验科血液标本出现误差的原因及探讨应对措施。方法:从我院2018年1月-2020年2月所进行过血液生化检验的血样中随机选取165例血液标本作为研究对象。将检验结果进行回顾性分析,研究探讨检验科血液标本出现误差的原因及应对措施。结果:165例血液标本中有23例标本不合格,不合格率为13.9%,导致血液标本不合格的最主要因素是采集操作不当,总共11例,在不合格血液标本中的占比为47.8%,其次为抗凝剂与血液量比例不当,例数为5例,在不合格血液标本中的占比为21.7%,数据差异具有统计学意义(P<0.05)。结论:检验科血液标本出现误差的原因主要有采集操作不当、保存时间过长、抗凝剂与血液量比例不当等,而血液检验在临床具有重要意义。因此,应加强注意影响检验结果准确性的相关因素,提高检验正确率,使患者能够及时得到正确的治疗方式。 相似文献
11.
Cheryl A. Young-Pelton Samantha L. Bushman 《Emotional and Behavioural Difficulties》2013,18(3):277-288
Effectiveness of a video self-modelling (VSM) intervention was examined with primary schoolchildren who attended a full-time special education programme for pupils with social emotional and behavioural difficulties and who exhibited inappropriate behaviour during small-group reading instruction. A randomised multiple-probe baseline design was used in this study in four subjects with a follow-up phase 6 weeks after intervention. Four children aged 10 were videotaped during reading instruction to determine levels of active learning and behavioural difficulties. Intervention took place at the teacher’s desk or table 3–5 minutes immediately before the child’s designated time for reading group instruction. During intervention, the children were shown carefully selected brief segments of their own video that had been recorded during the previous session. Results indicated VSM was an effective intervention for increasing active learning responses and for reducing behavioural difficulties during reading instruction. Optimum results were maintained for more than 8 weeks after intervention. These results support VSM as an effective antecedent intervention and add to the growing body of evidence-based practices for elementary school pupils who have social emotional and mental health difficulties. 相似文献
12.
目的 :研究盐性高血压大鼠血管平滑肌CaN活性变化。方法 :应用酶活性测定方法 ,对SD大鼠和盐性高血压大鼠的A、CA、MA血管平滑肌CaN进行活性比较。结果 :盐性高血压大鼠其不同血管CaN活性与其对照组相应血管酶活性变化无显著差异。而二组中CA活性明显低于A的活性 ,阻力血管MA活性却无明显降低。结论 :阻力血管平滑肌的CaN酶活性变化并非导致盐性高血压的直接原因。 相似文献
13.
本文回顾性研究和分析1991年1月至1997年5月经CT平扫证实的42例无偏瘫型脑出血患者．其结果表示：在42例病例中,对例（78.6％）大于60岁活动中起病35例（83.3％）．临床表现多种多样．38例入院时神志清醒,入院前与入院后CT平扫发现出血位于脑的不同部位,且量较少,约0．5～60ml（平均79±11.5ml,出血破入脑室10例（23.8％）本文显示：无偏瘫型脑出血临床症状多种多样,典型的症状不是很明显,所以给诊断带来困难．放对此类病人应尽早行头CT平扫,同时应详细采集病史和进行神经系统查体,以助确诊和避免误诊． 相似文献
14.
Di JZ Han XD Gu WY Wang Y Zheng Q Zhang P Wu HM Zhu ZZ 《Journal of Zhejiang University. Science. B》2011,12(10):805-811
Global DNA hypomethylation has been associated with increased risk for cancers of the colorectum, bladder, breast, head and
neck, and testicular germ cells. The aim of this study was to examine whether global hypomethylation in blood leukocyte DNA
is associated with the risk of hepatocellular carcinoma (HCC). A total of 315 HCC cases and 356 age-, sex- and HBsAg status-matched
controls were included. Global methylation in blood leukocyte DNA was estimated by analyzing long interspersed element-1 (LINE-1)
repeats using bisulfite-polymerase chain reaction (PCR) and pyrosequencing. We observed that the median methylation level
in HCC cases (percentage of 5-methylcytosine (5mC)=77.7%) was significantly lower than that in controls (79.5% 5mC) (P=0.004, Wilcoxon rank-sum test). The odds ratios (ORs) of HCC for individuals in the third, second, and first (lowest) quartiles
of LINE-1 methylation were 1.1 (95% confidence interval (CI) 0.7–1.8), 1.4 (95% CI 0.8–2.2), and 2.6 (95% CI 1.7–4.1) (P for trend <0.001), respectively, compared to individuals in the fourth (highest) quartile. A 1.9-fold (95% CI 1.4–2.6) increased
risk of HCC was observed among individuals with LINE-1 methylation below the median compared to individuals with higher (>median)
LINE-1 methylation. Our results demonstrate for the first time that individuals with global hypomethylation measured in LINE-1
repeats in blood leukocyte DNA have an increased risk for HCC. Our data provide the evidence that global hypomethylation detected
in the easily obtainable DNA source of blood leukocytes may help identify individuals at risk of HCC. 相似文献
15.
Automatic segmentation of bladder in CT images 总被引：1，自引：0，他引：1
Segmentation of the bladder in computerized tomography （CT） images is an important step in radiation therapy planning of prostate cancer. We present a new segmentation scheme to automatically delineate the bladder contour in CT images with three major steps. First, we use the mean shift algorithm to obtain a clustered image containing the rough contour of the bladder, which is then extracted in the second step by applying a region-growing algorithm with the initial seed point selected from a line-by-line scanning process. The third step is to refine the bladder contour more accurately using the rolling-ball algorithm. These steps are then extended to segment the bladder volume in a slice-by-slice manner. The obtained results were compared to manual segmentation by radiation oncologists. The average values of sensitivity, specificity, positive predictive value, negative predictive value, and Hausdorffdistance are 86.5%, 96.3%, 90.5%, 96.5%, and 2.8 pixels, respectively. The results show that the bladder can be accurately segmented. 相似文献
16.
袁小明 《泰州职业技术学院学报》2012,12(6):119-121
目的分析高血压治疗费用对高血压治疗控制率的影响,以提高高血压的控制率。方法以内科门诊近一年半以来高血压病患者看病就诊未能很好的控制血压的526例作为随访对象,按照临床高血压的治疗原则,根据患者的个体差异,血压未能控制者,适当增加原来口服药物的剂量或加服另一种降压药。结果265例患者经再次调整价格便宜的降压药物利血平后,部分患者下降明显,血压可以得到较好的控制。其中根据患者体质差异血压完全有效者达到156例,占总数的58．9％。结论针对经济困难的高血压患者,做出相应的对策将明显提高高血压患者的控制率。 相似文献
17.
目的探讨普通型2019冠状病毒病(COVID-19)患者的临床表现与高分辨率CT(HRCT)的影像特征。方法回顾性分析我院收治的25例COVID-19确诊患者的临床资料及胸部CT检查,进一步分析其临床特征、实验室指标及HRCT影像学特征。结果我院收治的25例COVID-19患者均为普通型,发热(19/25,76%),干咳(18/25,72%);所有患者白细胞计数均正常,淋巴细胞计数不同程度减少(15/25,60%),血沉增快(12/25,48%),C反应蛋白升高(10/25,40%),出现降钙素原降低(2/25,8%);平均住院日为19.8±3.9天,从出现临床症状到CT检查阳性平均时间为4.9±2.7天。首次胸部HRCT病灶分布为单侧9例(36%,左肺4/25,16%;右肺5/25,20%),双侧16例(64%);20例(80%)病灶分布位于周边,5例(20%)位于周边为主及中心同时受累。HRCT表现中单纯磨玻璃影(GGO)为25例(100%),GGO伴局灶性实变为5例(20%),4例(16%)伴片状实变影。在第二次HRCT检查中,大部分患者病灶增多、范围变广,局部病灶融合,并见支气管充气征。结论普通型COVID-19患者临床表现相对较轻,HRCT是其诊断和评估的重要手段。 相似文献
18.
目的探讨内镜粘膜下剥离术治疗食管病变的护理配合。方法护士负责术中器械传递和设备调节,配合医生进行内镜下黏膜剥离术。结果30例病灶病变均达到完全剥离,所有患者术中均未出现大出血及穿孔等严重并发症,其中1例患者出现迟发性出血,于内镜下再次止血。结论医护的良好配合,可以缩短检查治疗时间,减少并发症,提高手术成功率。 相似文献
19.
天麻钩藤饮对高血压病肝阳上亢证患者超氧化物歧化酶的影响 总被引：4，自引：0，他引：4
目的：观察天麻钩藤饮对高血压病（肝阳上亢型）患者血浆超氧化物歧化酶（SOD）的影响。方法：采用随机对照方法，观察天麻钩藤饮组（30例）和对照组（30例）治疗前后血压水平及血浆超氧化物歧化酶的变化。结果：两组治疗后血压明显降低，超氧化物歧化酶明显增高（P〈0．01，P〈0．05），组间比较无显著差异（P〉0．05）。结论：天麻钩藤饮能显著升高高血压病患者血浆超氧化物歧化酶的水平。 相似文献
20.
Stephen Houghton Nikki Milner John West Graham Douglas Vivienne Lawrence Ken Whiting Rosemary Tannock Kevin Durkin 《British journal of educational technology : journal of the Council for Educational Technology》2004,35(1):21-34
The motor control of 49 unmedicated boys clinically diagnosed with ADHD, case‐matched with 49 non‐ADHD boys, was assessed while playing Crash Bandicoot I, a SonyTM Playstation platform computer video game. In Crash Bandicoot participants control the movements of a small‐animated figure through a hazardous jungle environment. Operationally defined measures of motor control were designated by (1) the stage of the game completed (ie, the number of obstacles successfully passed) before losing the figure's ‘life’, (2) the level of complexity that the stage represented and (3) the time taken to get to that point during the video game play. These measures were assessed under contrasting conditions of low or high working memory and distracter loads. Four tasks were administered (totalling 12 trials), incorporating both with and without distracter conditions. For those trials with the distracter, a segment of the television show The Simpsons was simultaneously played on a television screen adjacent to the computer game monitor. A 5‐way MANOVA revealed that ADHD boys took less time to complete their trials under the direct condition (ie, no working memory load) on Crash Bandicoot, compared to their matched non‐ADHD peers. When the task required additional working memory, however, the ADHD boys took significantly longer. Cumulative frequency plots of game performance revealed that in terms of the number of obstacles completed, the control participants successfully navigated more obstacles on the low working memory load task than the ADHD participants, but that the performance of the two groups was less distinguishable on the high working memory load task. The findings have implications for assessment and management of children with ADHD. 相似文献