The neural correlates of working memory training in typically developing children     

Jonathan S. Jones  Anna-Lynne R. Adlam  Abdelmalek Benattayallah  Fraser N. Milton 《Child development》2022,93(3):815-830

Working memory training improves children's cognitive performance on untrained tasks; however, little is known about the underlying neural mechanisms. This was investigated in 32 typically developing children aged 10–14 years (19 girls and 13 boys) using a randomized controlled design and multi-modal magnetic resonance imaging (Devon, UK; 2015–2016). Training improved working memory performance and increased intrinsic functional connectivity between the bilateral intraparietal sulci. Furthermore, improvements in working memory were associated with greater recruitment of the left middle frontal gyrus on a complex span task. Repeated engagement of fronto-parietal regions during training may increase their activity and functional connectivity over time, affording greater working memory performance. The plausibility of generalizable cognitive benefits from a neurobiological perspective and implications for neurodevelopmental theory are discussed.  相似文献   

数字内容产品版权保护的演化博弈分析     

赵艳  王文举  倪渊 《图书情报工作》2019,63(2):43-51

[目的/意义]基于版权保护的演化博弈分析，有助于探究数字内容产品的原创主体对仿冒行为是否具有容忍度，以及不同仿冒水平下实施版权保护的策略选择，对规范数字内容产品市场主体行为具有一定指导意义。[方法/过程]首先借助演化博弈模型，分析原创主体与仿冒主体的利益演化过程，探究版权保护下原创主体对仿冒水平的容忍行为；然后通过细化博弈双方的利润函数模型，探究原创主体容忍度水平的决定因素。[结果/结论]原创主体对较小的仿冒水平存在一定的容忍度，对较高的仿冒水平零容忍。最大仿冒水平容忍度由仿冒交叉收益系数、收益模型常系数、产品研发成本系数和原创主体的产品研发努力水平倍数4个因素共同决定。  相似文献   

Genetic Polymorphism of Angiotensin II Type 1 Receptors and Their Effect on the Clinical Outcome of Captopril Treatment in Arab Iraqi Patients with Acute Coronary Syndrome (Mid Euphrates)     

Fadhaa A. Ghafil  Bassim I. Mohammad  Hussain S. Al-Janabi  Najah R. Hadi  Hayder A. Al-Aubaidy 《Indian journal of clinical biochemistry : IJCB》2021,36(1):81

Genetic variation in the angiotensin II type 1 receptor (AT1R) has an important effect on the outcome of acute coronary syndrome (ACS) initiated treatment with captopril. This study aims to investigate the impact of genetic polymorphism of AT1R (rs5186 and rs275651) on the ACS outcome in Iraqi patients treated with captopril. A total of 250 Iraqi individuals with ACS were included in this case—control study and they were divided into two study groups; Study group 1 included 125 participants who were prescribed captopril, 25 mg twice daily and study group 2 included 125 participants who received no captopril as part of their ACS treatment (control study). The AT1R gene (rs5186) CC genotype was found to be associated with ST-elevation myocardial infarction (STEMI) (Odd’s ratio (O.R) = 1.2, P = 0.7), while AC was associated with Non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA) (O.R = 1.2, P = 0.8). AC genotype is more prone to have Percutaneous coronary intervention (PCI) after ACS attack (O.R = 1.2, P = 0.6). CC genotype had a risk to get less improvement (O.R = 1.6, P = 0.5), so might require higher doses of captopril during acute coronary insult. The AT1R gene (rs275651) AA genotype was associated with UA (O.R = 1.3, P = 0.9). AA and AT genotypes were more prone to have PCI after ACS attack (O.R = 3.9 P = 0.2, O.R = 3.5, P = 0.3 respectively) and thus requiring higher doses of captopril. We conclude that the AT1R rs5186, rs275651 genetic polymorphisms might partially affect the clinical outcome of ACS patients treated with captopril and might have captopril resistance which requires higher doses.  相似文献   

Digital Module 16: Longitudinal Data Analysis     

Jeffrey R. Harring  Tessa L. Johnson 《Educational Measurement》2020,39(3):137-138

In this digital ITEMS module, Dr. Jeffrey Harring and Ms. Tessa Johnson introduce the linear mixed effects (LME) model as a flexible general framework for simultaneously modeling continuous repeated measures data with a scientifically defensible function that adequately summarizes both individual change as well as the average response. The module begins with a nontechnical overview of longitudinal data analyses drawing distinctions with cross-sectional analyses in terms of research questions to be addressed. Nuances of longitudinal designs, timing of measurements, and the real possibility of missing data are then discussed. The three interconnected components of the LME model—(1) a model for individual and mean response profiles, (2) a model to characterize the covariation among the time-specific residuals, and (3) a set of models that summarize the extent that individual coefficients vary—are discussed in the context of the set of activities comprising an analysis. Finally, they demonstrate how to estimate the linear mixed effects model within an open-source environment (R). The digital module contains sample R code, diagnostic quiz questions, hands-on activities in R, curated resources, and a glossary.  相似文献   

多旋翼无人机微多普勒特性分析与特征提取     

马娇  董勇伟  李原  李凌霄  杨杰芳 《中国科学院大学学报》2019,36(2):235-243

针对多旋翼无人机目标的识别问题，提出一种基于伽柏（Gabor）变换的瞬时频率估计与快速傅里叶变换（FFT）相结合的微多普勒特征提取算法。首先建立多旋翼无人机旋翼回波模型，并通过仿真分析叶片数目、旋翼转速和初始相位等参数对微多普勒特征的影响，利用Gabor变换得到时频特征。在此基础上通过瞬时频率极大值法提取微多普勒频率，并对瞬时频率采用FFT提取旋翼数和转动频率，从而获得叶片长度估计值。实测数据验证了该算法较为准确地提取无人机的微多普勒参数。  相似文献   

Food (in)security communication: a Journal of Applied Communication Research forum addressing current challenges and future possibilities     

Megan K. Schraedley  Hamilton Bean  Sarah E. Dempsey  Mohan J. Dutta  Kathleen P. Hunt  Sonia R. Ivancic 《Journal of Applied Communication Research》2020,48(2):166-185

ABSTRACT

This forum brings together food, (in)security, and communication. The authors participating in this forum center communication as both process and tool for understanding, mitigating, and making meaning of food (in)security. The nine authors together discuss the role of communication in food (in)security, the central challenges for scholars and practitioners working on food (in)security, and the creative possibilities and impacts influencing the future of food (in)security. The forum produces a call for applied scholars to re-imagine communication frameworks in order to make meaningful differences in their communities.  相似文献   

供给侧视阈下分级诊疗制度的研究     

吴尔  袁德娟 《呼伦贝尔学院学报》2020,28(1):29-34

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试论大学体育宽口径教学     

龚元方 《湖北体育科技》2003,22(1):110-111

大学生良好的身体状况对提高他们的工作效率是非常有益的。良好的身体状况需要通过体育锻炼来实现。但是，由于学生的运动能力不足和体育知识不够丰富，影响了参与体育活动的积极性。而高校体育设施完备、师资力量雄厚，可以保证体育教学多项目地开展，从而保证体育宽口径教学的实施。  相似文献   

Voice: the search for a feminist rhetoric for educational studies∗     

Madeleine R. Grumet 《Cambridge Journal of Education》1990,20(3):277-282

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论高校体育教学中的德育教育   总被引：1，自引：0，他引：1  

程禹  原立仁 《吉林体育学院学报》2006,22(2):5-6

随着社会的变革和发展，给德育赋予以新的内容、新的思想。在市场经济迅速发展、大力提倡素质教育的今天．整个教育面临着新的问题。通过对高校体育教学特点的分析，以及对高校体育教学中德育内容的探讨，提出在高校体育教学中进行德育渗透的途径与方法。  相似文献