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BackgroudBlood flow restriction (BFR) with low-intensity resistance training has been shown to result in hypertrophy of skeletal muscle. In this study, we tested the hypothesis that BFR during the rest periods between acute, high-intensity resistance exercise sessions (70% of 1 repetition maximum, 7 sets with 10 repetitions) enhances the effects of the resistance training.MethodsA total of 7 healthy young men performed squats, and between sets BFR was carried out on one leg while the other leg served as a control. Because BFR was applied during rest periods, even severe occlusion pressure (approximately 230 mmHg), which almost completely blocked blood flow, was well-tolerated by the participants. Five muscle-specific microRNAs were measured from the biopsy samples, which were taken 2 h after the acute training.ResultsDoppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR. microRNA-206 levels significantly decreased in the BFR leg compared to the control. The mRNA levels of RAC-β serine/threonine-protein kinase v22, nuclear respiratory factor 1, vascular endothelial growth factor, lupus Ku autoantigen protein p70 genes (p < 0.05), and paired box 7 (p < 0.01) increased in the BFR leg. The protein levels of paired box 7, nuclear respiratory factor 1, and peroxisome proliferator-activated receptor γ coactivator 1α did not differ between the BFR leg and the control leg.ConclusionBFR, during the rest periods of high-load resistance training, could lead to mRNA elevation of those proteins that regulate angiogenesis, mitochondrial biogenesis, and muscle hypertrophy and repair. However, BFR also can cause DNA damage, judging from the increase in mRNA levels of lupus Ku autoantigen protein p70.  相似文献   
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The way of life of top athletes imposes a burden exceeding the average not only on the biological but also on the psychological level. Apart from somatic problems, this may result in psychological disturbances which necessitate psychotherapeutic treatment. To achieve peak performance, both somatically and mentally superior levels of health and strength are needed. On the basis of this conviction, 50 first class young sportsmen were prepared over a period of 6–8 months, using procedures such as autogenic training, imaginative psychotherapy, imaginative mental training and training on altered states of consciousness.‐Results indicated that these athletes suffered fewer injuries, were less often absentfrom training, obtainedfewer competition results below their training performance and showed more frequent improvement of performance. These findings show that psychotherapeutic work with top athletes can be a useful part of their preparation.  相似文献   
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It has been proposed that sensitivity to the parameters underlying speech rhythm may be important in setting up well-specified phonological representations in the mental lexicon. However, different acoustic parameters may contribute differentially to rhythm and stress in different languages. Here we contrast sensitivity to one such cue, amplitude envelope onset (rise time), in dyslexic and normally-developing children in two languages, Hungarian and English, ages from 7 to 11. Dyslexic and control children received phonological tasks, reading and spelling tasks and auditory processing tasks. While sensitivity to rise time was related to phonological representation in both languages, clear differences were found between languages. It is suggested that these differences may reflect differential language-specific weighting of different acoustic cues to rhythm and stress.
Valéria CsépeEmail:
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The restructuring of Hungarian higher education according to European expectations has resulted in fundamental changes. Due to the intensifying market and the decreasing number of applicants, institutions are interested in ensuring the necessary number of students. The objective of the study is to identify those schools where the greatest interest in the courses offered by the University of Szeged can be expected. The selection was based on spatial and temporal analysis of submitted applications using geographical information system methods. The results can contribute to attracting the necessary number of students and to developing a sound basis for future educational planning.  相似文献   
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In the beginning of the German occupation of Poland in 1939, press censorship and a strict ban on radio listening were imposed. Poles and ghettos-imprisoned Jews could obtain international information by reading German-controlled newspapers or, alternatively, by reading the clandestine press or listen to rumours. This article stresses the significance of information distributed by activists of Hashomer Hatzair, Zionist, leftist youth movement, who conducted radio monitoring and prepared daily news bulletins distributed in Warsaw ghetto. The article describes their monitoring practices and shows how news extracted from broadcasts was later used in the press. It also engages with the question as to why foreign news was so important to Jews struggling to survive in terrible conditions of the ghetto. It also identifies motivations for conducting radio monitoring during the Holocaust and compares it with those of people listening to foreign radio stations in other contexts and with different intentions.  相似文献   
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Changing social needs, and especially the rate of change itself, demand a fresh approach to educational theory and practice. Just as theory must draw on the findings of a wide range of sciences, so must practice ensure activity by the student and a reliable system of assessing attainment. Given the constraints to educational development, whether economic or behavioural, the author sees the introduction of educational technology as the only course for improving conditions. He adopts a wide definition of educational technology, to embrace a new applied pedagogical science and conceives it systemically.On the basis of this analysis, he describes as a practical example the creation of the Hungarian National Centre for Educational Technology in the 70's. With its main function in the area of research and development, the Centre carries out wide-ranging studies, ensures the collaboration of the specialists concerned in development of curricula, and then proceeds to the preparation of learning packages with a multi-media composition. After testing, the new materials and methods are disseminated, and here the Centre also plays an active role. It has promoted courses on educational technology at the pre-service and in-service teacher education levels, and carries out follow-up studies on the extent of application of the innovations it launches.
Zusammenfassung Sich ändernde soziale Bedürfnisse und insbesondere das Tempo der Veränderung selbst erfordern einen neuen Ansatz in Theorie und Praxis des Bildungswesens. Genau wie die Theorie auf den Ergebnissen einer ganzen Reihe Wissenschaften aufgebaut werden muß, hat die Praxis die Aktivität der Studenten zu gewährleisten sowie ein zuverlässiges System zur Evaluation des Erreichten. In Anbetracht der wirtschaftlichen oder durch Verhaltensweisen bedingten Beschränkungen einer Bildungsentwicklung sieht der Verfasser in der Einführung einer Bildungstechnologie den einzigen Weg zur Verbesserung der Bedingungen. Er definiert den Begriff Bildungstechnologie in sehr weitgefaßtem Sinn, so daß er eine neue angewandte Erziehungswissenschaft umfaßt und diese als System versteht.Aufgrund dieser Analyse schildert er als praktisches Beispiel die Schaffung des Ungarischen Nationalen Zentrums für Bildungstechnologie in den 70er Jahren. Während seine Hauptaufgaben im Bereich der Forschung und Entwicklung liegen, führt das Zentrum weitgehende Studien durch, sichert die Mitarbeit von Spezialisten auf dem Gebiet der Curriculum-Entwicklung und befaßt sich dann weiter mit der Vorbereitung von Lernmaterial in multi-medialer Zusammensetzung. Nach entsprechenden Tests werden die neuen Materialien un Methoden verbreitet, und auch dabei spielt das Zentrum eine aktive Rolle. Es hat Lehrgänge über Bildungstechnologie auf der Ebene der Vor- und Weiterbildung von Lehrern gefördert und führt danach Untersuchungen darüber durch, wie weit die von ihm in Gang gesetzten Neuerungen angewandt werden.

Résumé L'évolution des besoins sociaux et particulièrement la rapidité de cette évolution, exige une approche nouvelle de la théorie et de la pratique de l'éducation. Tout comme la théorie doit exploiter les découvertes d'un large éventail de sciences, la pratique doit assurer l'activité de l'étudiant et fournir un système éprouvé d'estimation des connaissances acquises. Etant donné les contraintes qui brident le développement de l'éducation — qu'elles soient provoquées par l'économie ou par le comportement — l'auteur estime que l'introduction d'une technologie de l'éducation est le seul moyen d'améliorer les conditions. Il définit largement la technologie de l'éducation comme une nouvelle science pédagogique appliquée et la conçoit de façon systématique.Se basant sur cette analyse, il donne en exemple la création, dans les années 70, du Centre National Hongrois de Technologie de l'Education. Ce Centre, dont les activités s'appliquent principalement au domaine de la recherche et du développement, et embrassent un champ très étendue d'études, s'assure la collaboration de spécialistes du développement des curricula puis procède à la préparation de packages avec un ensemble de moyens d'enseignement. Après expérimentation, les nouveaux matériels et les nouvelles méthodes sont disséminés et, à ce stade encore, le Centre joue à nouveau un rôle actif. Il crée et développe des cours de technologie de l'éducation aux niveaux de la formation professionnelle initiale ou en cours d'emploi des enseignants, et il organise des études longitudinales afin d'évaluer l'application des innovations apportées.
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