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Ferenc Torma Zoltan Gombos Marcell Fridvalszki Gergely Langmar Zsofia Tarcza Bela Merkely Hisashi Naito Noriko Ichinoseki-Sekine Masaki Takeda Zsolt Murlasits Peter Osvath Zsolt Radak 《运动与健康科学(英文)》2021,10(4):470
BackgroudBlood flow restriction (BFR) with low-intensity resistance training has been shown to result in hypertrophy of skeletal muscle. In this study, we tested the hypothesis that BFR during the rest periods between acute, high-intensity resistance exercise sessions (70% of 1 repetition maximum, 7 sets with 10 repetitions) enhances the effects of the resistance training.MethodsA total of 7 healthy young men performed squats, and between sets BFR was carried out on one leg while the other leg served as a control. Because BFR was applied during rest periods, even severe occlusion pressure (approximately 230 mmHg), which almost completely blocked blood flow, was well-tolerated by the participants. Five muscle-specific microRNAs were measured from the biopsy samples, which were taken 2 h after the acute training.ResultsDoppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR. microRNA-206 levels significantly decreased in the BFR leg compared to the control. The mRNA levels of RAC-β serine/threonine-protein kinase v22, nuclear respiratory factor 1, vascular endothelial growth factor, lupus Ku autoantigen protein p70 genes (p < 0.05), and paired box 7 (p < 0.01) increased in the BFR leg. The protein levels of paired box 7, nuclear respiratory factor 1, and peroxisome proliferator-activated receptor γ coactivator 1α did not differ between the BFR leg and the control leg.ConclusionBFR, during the rest periods of high-load resistance training, could lead to mRNA elevation of those proteins that regulate angiogenesis, mitochondrial biogenesis, and muscle hypertrophy and repair. However, BFR also can cause DNA damage, judging from the increase in mRNA levels of lupus Ku autoantigen protein p70. 相似文献
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Over the last decades more and more research has analysed relatively new or rediscovered teaching–learning concepts like blended, hybrid, multi-sensory or technologically enhanced learning. This increased interest in these educational forms can be explained by new exciting discoveries in brain research and cognitive psychology, as well as by the accelerated integration of technology (computers, intranets, internet, etc.) in education. We have investigated how the educationally valuable outcomes of these trends could be implemented in computer-programming education and in what ways this process could be catalysed by arts (dance, music, rhythm, theatrical role-playing). We present a theoretical basis for technologically and artistically enhanced multi-sensory teaching–learning strategies. This work focuses particularly on how dance can be involved in computer science classes. 相似文献
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Educational technology research and development - We proposed to investigate whether properly calibrated e-learning environments can efficiently promote computational thinking of both sciences- and... 相似文献
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Zoltan Varga Nicholas McGuinn Amanda Naylor Hege Emma Rimmereide Ghazal Kazim Syed 《Cambridge Journal of Education》2020,50(4):501-519
ABSTRACT Using William Golding’s Lord of the Flies as a stimulus, researchers from Norway, Pakistan and the United Kingdom explored the potential of a literary text to encourage intercultural dialogue. The innovative research method used was to combine Literature Circles and Google Documents to provide a platform for asynchronous online exchange between three cohorts of students in higher education. The authors’ analysis of the data suggested differences between those students who regarded the text as a living document speaking directly to their personal experiences of citizenship issues and those for whom the novel remained a historical document, removed from their lived experience. The authors contend that this research can contribute original and significant insights to the literature on teaching citizenship through literary texts such as the relationship between text choice and context, models of international collaboration at the higher education level and contrasting approaches towards citizenship and reading. 相似文献
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Zoltan P. Majdik 《Technical Communication Quarterly》2019,28(3):207-222
The goal of this paper is to consider rhetorical effects as the propagation of rhetorical expressions across large sets of texts, measured by the extent to which rhetorical expressions, structures, or practices become replicated in texts and sites of rhetorical in(ter)vention. The paper draws on lines of scholarship in the digital humanities and computational rhetoric – primarily, sequential structuring of semantic contexts, semantic parsing of unstructured text, and diachronic tracking of textual expressions – to extend their conceptual and methodological insights into a computational framework for assessing rhetorical effectiveness. It offers a test case for this concept through an analysis of how Congress has framed human agency toward addressing climate change. 相似文献
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Three studies tested the notion that rats would treat brain-stimulation reward (BSR) as a stimulus alphabet from which rules could be abstracted to learn serial patterns. In Experiment 1, rats learned to track a serial pattern of 18-10-6-3-1-0 pulses of BSR, responding fast in anticipation of large quantities of BSR and slowly or not at all in anticipation of small quantities of BSR. In Experiment 2, rats learned to track a formally simple 18-6-1-0 pattern faster than a formally complex 18-1-6-0 pattern in a within-subjects procedure, indicating that rats can learn to discriminate between simple and complex pattern structures. Finally, in Experiment 3 rats learned either a formally simple 25-18-10-3-1-0 or a formally complex 25-3-10-18-1-0 pattern whose successive elements were separated by an embedded three-element 6-6-0 subpattern. Rats learned to “chunk together” the dispersed pattern elements, and rats receiving the simple pattern learned to track their pattern, whereas rats receiving the complex pattern did not. The latter results suggest that when simple pattern structure is available, rats can simultaneously track rule structures in at least two memory locations. The results of these experiments, using a new testing procedure and, presumably, a new stimulus alphabet, generalize and extend the idea that rats can abstract relational rules to learn serial patterns. 相似文献
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This paper explores the rhetorical basis of a major paradigm change in meteorology, from a focus on inductive observation to deductive, mathematical reasoning. Analysis of Cleveland Abbe's “The Physical Basis of Long-Range Weather Forecasts” demonstrates how in his advocacy for a new paradigm, Abbe navigates the tension between piety to tradition and dissent necessary for innovation through the rhetorical imagination of and appeal to a disciplinary telos. This strategy allows him to dismiss the traditions of meteorology while simultaneously creating common ground between a new paradigm and an audience of contemporary scientists whose traditions he rejects. 相似文献
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