Connecting inside out: Development of the social brain in infants and toddlers with a focus on myelination as a marker of brain maturation     

Nora Schneider  Elizabeth Greenstreet  Sean C. L. Deoni 《Child development》2022,93(2):359-371

Early childhood is a sensitive period for learning and social skill development. The maturation of cerebral regions underlying social processing lays the foundation for later social-emotional competence. This study explored myelin changes in social brain regions and their association with changes in parent-rated social-emotional development in a cohort of 129 children (64 females, 0–36 months, 77 White). Results reveal a steep increase in myelination throughout the social brain in the first 3 years of life that is significantly associated with social-emotional development scores. These findings add knowledge to the emerging picture of social brain development by describing neural underpinnings of human social behavior. They can contribute to identifying age-/stage-appropriate early life factors in this developmental domain.  相似文献   

数字内容产品版权保护的演化博弈分析     

赵艳  王文举  倪渊 《图书情报工作》2019,63(2):43-51

[目的/意义]基于版权保护的演化博弈分析，有助于探究数字内容产品的原创主体对仿冒行为是否具有容忍度，以及不同仿冒水平下实施版权保护的策略选择，对规范数字内容产品市场主体行为具有一定指导意义。[方法/过程]首先借助演化博弈模型，分析原创主体与仿冒主体的利益演化过程，探究版权保护下原创主体对仿冒水平的容忍行为；然后通过细化博弈双方的利润函数模型，探究原创主体容忍度水平的决定因素。[结果/结论]原创主体对较小的仿冒水平存在一定的容忍度，对较高的仿冒水平零容忍。最大仿冒水平容忍度由仿冒交叉收益系数、收益模型常系数、产品研发成本系数和原创主体的产品研发努力水平倍数4个因素共同决定。  相似文献   

Does modality matter? A latent profile and transition analysis of sedentary behaviours among school-aged youth: The UP&DOWN study     

David Sánchez-Oliva  Rebecca M. Leech  Alberto Grao-Cruces  Irene Esteban-Cornejo  Carmen Padilla-Moledo  Oscar L. Veiga 《Journal of sports sciences》2020,38(9):1062-1069

ABSTRACT

The aims of this study were to identify profiles of sedentary behaviour (SB) patterns, based on leisure-time self-reported SB modalities (screen, educative, social, and relaxing) and to evaluate changes in these profiles over 2 years among Spanish youth aged 8–18 years. Latent profile analysis (LPA), a data-driven analytic approach, was used to identify groups of boys and girls (n = 1553; 48% girls; mean±SD age: 12.56 ± 2.49 y) with distinct SB profiles using the SB modalities (time/d) as input variables. Latent transition analysis, an extension of LPA that uses longitudinal data, was used to analyse 2-year changes in these profiles. At baseline, four and three SB profiles were found among boys (labelled: screen, educative, social, and relaxing) and girls (labelled: screen/social, educative, and relaxing), respectively. Overall, more girls (range: 48%-67%) had the same profile over time, than boys (40%-52%). Participants with a screen or relaxing SB profile at baseline were more likely to have an educative profile after 2 years. Youth with a social and an educative SB profile at baseline were more likely to transition to profiles characterized by higher screen and social SB, respectively. Using a novel and person-centered approach, this study identified gender-specific SB profiles that were moderately stable over time.  相似文献   

‘Just stick to the science’ is not enough     

Peterson  Erik L. 《Metascience》2019,28(1):147-150

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图书流通数据分析的H类指数遴选及应用——以西北农林科技大学图书馆为例     

净玲娣  王立宏  王芹  李雅 《图书情报工作》2020,64(9):65-72

[目的/意义] 优化藏书采访工作和流通管理，实现对藏书采访、藏书总量和结构等状况适时监测、评估、调控等的标准化管理。[方法/过程] 通过对H类指数中的H指数、A指数和G指数相关性、变异性和适应性分析，遴选适用于图书流通数据分析的A指数，并根据帕累托定律采用A指数对西北农林科技大学图书馆2014-2018年的前20%的图书流通数据分别进行统计分析。[结果/结论] 研究结果表明：平均A指数对中图法一级类目与读者性别、读者专业、读者年级以及图书出版社、图书出版年、单位等数据统计分析具有较理想的表现，能够更全面、准确地遴选核心读者群、核心出版者和核心出版年；同时发现，布拉德福定律不仅能够应用于期刊管理，而且能够应用于藏书管理。本文研究能够为探索H类指数分析高校图书馆藏书流通数据提供参考依据。  相似文献   

基于二模复杂网络的隐性知识发现方法研究——以潜在药物靶点挖掘为例     

李东巧  陈芳  韩涛  杨艳萍  王学昭  王燕鹏  Cynthia Liu  Yingzhu Li 《图书情报工作》2020,64(21):120-129

[目的/意义] 通过构建二模复杂网络模型，揭示隐藏在海量文献中的隐性知识。[方法/过程] 通过NetworkX复杂网络工具包，依据任意两个节点的共现关系构建二模复杂网络模型；对网络模型中节点的共现关系进行加权，计算网络的拓扑信息并进行AP聚类，提取节点间的直接关系；采用AUC方法对AA、JC、加权改进的wAA和wJC等4种链路预测算法进行评价，遴选出最合适的预测算法，并对复杂网络的隐性关系进行预测分析。[结果/结论] 以潜在药物靶点挖掘为例进行的实证研究结果表明，wAA链路预测算法为最优的链路预测算法；二模复杂网络模型、指标和方法体系在美国化学文摘社数据库中的药物靶点挖掘中具有一定的有效性。下一步计划在其他数据库中或其他研究领域中进行尝试，以进一步验证该模型的通用性和有效性。  相似文献   

教材史料应用策略刍议——以部编高中教材“辽宋夏金元的经济与社会”为例     

汪茉莉 《历史教学(高校版)》2020,(1):14-18

教材史料简言之即是教材中的史料,部编教材《中外历史纲要》的显著特点是纲要式的正文配以形式多样、种类丰富的史料。纲要式体裁决定了正文非常简练,是对历史脉络的勾画,这种勾画对于高中生学习历史来说未免枯燥、单一。好在部编教材配以丰富的史料,这些教材史料正好弥补了教材正文的简练,使历史学习变得有血有肉。  相似文献   

Digital Module 16: Longitudinal Data Analysis     

Jeffrey R. Harring  Tessa L. Johnson 《Educational Measurement》2020,39(3):137-138

In this digital ITEMS module, Dr. Jeffrey Harring and Ms. Tessa Johnson introduce the linear mixed effects (LME) model as a flexible general framework for simultaneously modeling continuous repeated measures data with a scientifically defensible function that adequately summarizes both individual change as well as the average response. The module begins with a nontechnical overview of longitudinal data analyses drawing distinctions with cross-sectional analyses in terms of research questions to be addressed. Nuances of longitudinal designs, timing of measurements, and the real possibility of missing data are then discussed. The three interconnected components of the LME model—(1) a model for individual and mean response profiles, (2) a model to characterize the covariation among the time-specific residuals, and (3) a set of models that summarize the extent that individual coefficients vary—are discussed in the context of the set of activities comprising an analysis. Finally, they demonstrate how to estimate the linear mixed effects model within an open-source environment (R). The digital module contains sample R code, diagnostic quiz questions, hands-on activities in R, curated resources, and a glossary.  相似文献   

From structure to function: unveiling the structure of the Nav channel–toxin complex     

Zhuan Zhou  Zuying Chai  Changhe Wang 《国家科学评论(英文版)》2019,6(5):859

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专题情报数据管理与智能分析平台的构建     

于倩倩  钱力  程冰  常志军  王慧丽  靳茜 《图书情报工作》2020,64(24):92-105

[目的/意义] 面对多学科领域、多类型用户的专题情报服务需求，建立专题情报数据管理与智能分析平台。实现专题情报分析的流程化和智能化，同时对融入专家智慧的专题情报分析过程数据进行管理，丰富服务模式，提升服务需求响应速度。[方法/过程] 在调研已有相关研究与实践分析基础上，提出平台设计思路、建设框架，对平台主要功能和关键技术进行剖析。[结果/结论] 专题情报数据管理与智能分析平台已建设完成。平台集成了多来源多类型数据，打通了从数据到分析的服务链条。嵌入了多种情报分析方法和深度学习算法，实现了多维多层次分析服务。能够对分析过程和情报分析人员历史积累数据进行管理，实现数据共享和重复利用。  相似文献