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1.
Abstract

Supporting global health priorities through the development of robust health science librarianship partnerships is of significant importance. Increased demand for synthesizing evidence-based information, collating quality resources, and increasing research productivity to improve human health requires integration of library and information science skills and expertise. The Health Sciences Library (HSL) at the University of North Carolina at Chapel Hill (UNC), exists to be an indispensable partner in health information and knowledge, teaching and learning, and research. As global efforts at UNC expanded, the HSL sought to ensure that our global engagement strategy and integration were aligned with campus priorities and partner needs. The HSL created a global research partnership plan: identify resources that improve efficiency, increase access to information, build in-country capacity and expertise—all while strengthening collaborations across multiple countries. Creating a meaningful and sustainable engagement strategy was central to envisioning our path forward and can be used as a framework for consideration by librarians in similar settings.  相似文献   
2.
目的:探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法:将雄性Wistar大鼠50只随机均分为5组:安静对照组(C)、低负荷运动训练组(LT)、中等负荷运动训练组(MT)、高负荷运动训练组(HT)和极高负荷运动训练组(ST),每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后,取腓肠肌样本,提取线粒体,测定线粒体柠檬酸合成酶(CS)、异柠檬酸脱氢酶(ICD)和α-酮戊二酸脱氢酶(α-KGDHC)活性;线粒体Ga2+含量、胞浆NADH、NAD+、ATP和ADP含量,以及ICD mRNA转录水平。结果:(1)不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组(P < 0.01),且CS和ICD活性由高到低顺序均为:MT组 > HT组 > ST组 > LT组 > C组,α-KGDHC活性由高到低顺序为:HT组 > MT组 > ST组 > LT组 > C组。(2)不同负荷运动训练组线粒体Ca2+ 含量均显著高于安静对照组(P < 0.01),其含量由高到低顺序为:MT组 > HT组 > ST组 > LT组 > C组;胞浆NADH/NAD+和ATP/ADP的比值均显著低于安静对照组(P < 0.01),其比值由低到高顺序为:MT组 < ST组 < HT组 < LT组 < C组。(3)不同负荷运动训练组ICD mRNA转录水平均高于安静对照组(P < 0.01),其水平由高到低顺序为: MT组 > HT组 > ST组 > LT组 > C组。结论:低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能,且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD+和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。  相似文献   
3.
ABSTRACT

News nonprofits in the U.S. have been proliferating over 15 years as a way of addressing troubles in the business model for news. For these newsrooms, collaboration, with each other and with mainstream news, has emerged as a key way to build readership and attain relevance in a crowded media space. Still, past research has told us that the strong connection to mainstream news has constrained these organizations’ critique of journalism. In Europe, nonprofit news remains nascent and represents a response to declining trust in and engagement with journalism, and rising populism across the continent. Against this very different context, this study examines two players at the forefront of the European news nonprofit movement. It demonstrates the path dependency inherent in the origins of these organizations: In Europe, they are a response to a different societal change, and thus developed rather differently than did their peers in the United States, with a focus on redefining the idea of collaboration and the role of their audiences by seeing citizens as collaborators, both in the creation and in the dissemination of news. By seeing citizens as collaborators, not just readers, they work to empower and build news audiences as well as participants.  相似文献   
4.
Although there has been a great deal of research into Collaborative Information Retrieval (CIR) and Collaborative Information Seeking (CIS), the majority has assumed that team members have the same level of unrestricted access to underlying information. However, observations from different domains (e.g. healthcare, business, etc.) have suggested that collaboration sometimes involves people with differing levels of access to underlying information. This type of scenario has been referred to as Multi-Level Collaborative Information Retrieval (MLCIR). To the best of our knowledge, no studies have been conducted to investigate the effect of awareness, an existing CIR/CIS concept, on MLCIR. To address this gap in current knowledge, we conducted two separate user studies using a total of 5 different collaborative search interfaces and 3 information access scenarios. A number of Information Retrieval (IR), CIS and CIR evaluation metrics, as well as questionnaires were used to compare the interfaces. Design interviews were also conducted after evaluations to obtain qualitative feedback from participants. Results suggested that query properties such as time spent on query, query popularity and query effectiveness could allow users to obtain information about team's search performance and implicitly suggest better queries without disclosing sensitive data. Besides, having access to a history of intersecting viewed, relevant and bookmarked documents could provide similar positive effect as query properties. Also, it was found that being able to easily identify different team members and their actions is important for users in MLCIR. Based on our findings, we provide important design recommendations to help develop new CIR and MLCIR interfaces.  相似文献   
5.
Abstract

This paper provides a methodology to study the characteristics of the research output from a university department. The faculty publications and their cited references over a 10-year period were used as the basis for this study to identify their publishing patterns and the types of material they are publishing; a core set of journals and other resources they are publishing in and citing over this period; the characteristics of the journals in which they publish and cite; the degree of openness of their publications and their citation advantage; and the age of resources that are referenced.  相似文献   
6.
略论现代体育教学过程中学生创新能力的培养   总被引:2,自引:0,他引:2  
体育与健康课程教学以“健康第一”为核心,以全面提高学生素质为目标,是培养学生创新能力的重要环节。创设体育课堂教学的民主协作氛围,保障学生心理的自由和安全,构建以人为本,以动机、兴趣、情感、意志为基本内容的激励体系,为培养和发展学生的创新能力提供良好的心理环境。  相似文献   
7.
校园网络系统在学校的教学和管理工作中发挥着越来越重要的作用,本文从当前Internet/Intranet及MIS系统的发展出发,在比较当前流行的数据存取及信息处理技术基础上,阐述TASP的作用与优点及其在校园网信息处理中的应用。  相似文献   
8.
邢傲伟跳马侧手翻直体侧空翻转体810°的运动学分析   总被引:7,自引:3,他引:4  
通过运动学等研究方法,揭示了我国优秀运动员邢傲伟完成的跳马侧手翻直体侧空翻转体810°的运动学规律与技术特点,对于进一步发展笠松类高难动作,提高我国男女跳马技术水平有促进作用.  相似文献   
9.
10.
根据工况将不同的设备组合成不同的工作流程,以集散控制技术为基础,应用PLC网络实现了对输煤设备的现场控制、电控室控制和中控室控制。并以FIX软件为工具,通过定义PLC的I/O端口映射表方法,以时间、事件、故障为触发手段,设计了实时监控软件,并实现了输煤量与数据库系统的数据接口。  相似文献   
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