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目的:研究软肝散对慢性乙型肝炎肝纤维化的治疗效果.方法:选取180例慢性乙型肝炎患者为研究对象,随机分两组,治疗组给予益肝灵和软肝散口服,对照组给予益肝灵口服,治疗6个月后评定疗效.主要观察项目为治疗前后患者的临床症状、体征、肝功能(AST、ALT、A/G)和血清肝纤维化指标(HA、LN、PCⅢ、Ⅳ-C)的变化情况.结果:两组病例治疗后临床主要症状、体征、肝功能和肝纤维化指标较治疗治疗前均有较大改善,治疗组总有效率为91.11％,对照组总有效率为80％,治疗组效果明显好于对照组.结论:软肝散在治疗慢性乙型病毒性肝炎肝纤维化方面具有明显缓解临床症状和体征,改善肝功能及肝纤维化指标的作用,值得在临床上推广使用. 相似文献
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肝纤维化是各种原因肝损伤后引起的肝脏复杂病理变化,国内外近年来研究表明,如果积极干预,尤其是在早期介入阻断肝纤维化的进展,甚至可以在一定程度上逆转肝纤维化,因此明确肝纤维化的诱发因素、发展机制及其可逆指标的检测对治疗慢性肝病肝纤维化即预防肝纤维化进展为肝硬化有一定的意义.但是目前肝纤维化的发生进展的机制仍未有较为明确的定论.文章通过研究近年来阐述肝纤维化发生、发展机制相关的文献,并对文献中有证据支持的肝纤维化发展过程中的相关机制做总结归纳,为肝纤维化的治疗及验证肝纤维化相关实验设计提供思路及理论支持. 相似文献
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目的:探讨抗肝腹水浸膏对鼠肝纤维化及利尿作用的影响.方法:1、小鼠肝纤维化试验:采用20%、40%CCL4橄榄油溶液,皮下注射制作小鼠肝纤维化模型后给药6周,测定肝组织羟脯氨酸含量,计算肝、脾指教并作病理检查.2、大鼠利尿试验:取试验前禁食18hr大鼠,分别给大鼠灌胃用生理盐水配成的药液50ml/kg,立即放入代谢笼内,收集6hr内的尿液,观察其大鼠6hr的排尿量与灌胃量比值.结果:1、小鼠肝纤维化试验:工艺Ⅱ高、工艺Ⅲ中、Ⅲ高和马洛替酯组小鼠肝组织羟脯氨酸含量下降,工艺Ⅱ中、工艺Ⅲ低和马洛替酯组小鼠血清透明质酸含量下降,工艺Ⅰ高、工艺Ⅱ中和马洛替酯组小鼠脾指数下降,与模型组比较,差异有显著和非常显著性意义(p＜0.05和p＜0.01).病理组织学检查:工艺Ⅰ低、工艺Ⅱ高、工艺Ⅲ低、Ⅲ中、复方鳖甲软肝片组和马洛替酯片组炎症细胞逐渐减少,点状坏死和交性范围缩小,有明显的纤维组织增生,与模型组比较,差异有显著和非常显著性意义(p＜0.05和p＜0.01).2、从大鼠利尿试验:工艺Ⅰ低、工艺Ⅱ低、工艺Ⅲ低、呋塞米片组在2hr的排尿量和排尿量与灌胃量比值均增;工艺Ⅰ低、工艺Ⅱ低、呋塞米片组在6hr的排尿量和排尿量与灌胃量比值均增加,但与空白组比较,均无显著性差异(p＞0.05).结论:工艺Ⅱ供试品,具有抑制肝纤维化及利尿作用. 相似文献
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用热激放电电流技术研究了具有微相分离结构的聚乙二醇型多嵌段聚醚氨酯脲的驰豫行为，通过浇铸ＰＥＵＵ的Ｎ，Ｎ－二甲基乙酰胺溶液所得的ＰＥＵＵ薄膜，其ＴＳＤＣ谱显示４个峰发现这些峰与软段的分子运动即氧亚乙基序列的局部运动、微布朗运动引起的玻璃化转变，Ｍａｘｗｅｌｌ－Ｗａｇｎｅｒ－Ｓｉｌｌａｒｓ界面极化以及各种带电离子的迁移密切相关，这些．实验结果已经证明，ＴＳＤＣ分析是研究高分子固态离子导体的一种有价值 相似文献
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肝纤维化是各种慢性肝病向肝硬化发展的必经途径。中医药对肝纤维化的理论及治疗有独到见解。目前中医药抗肝纤维化的研究取得了丰硕成果。 相似文献
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宋代儿科名医钱仲阳，取张仲景肾气丸(八味地黄丸)减去附子、桂枝，以熟地黄易干地黄，成为六味地黄丸，用治小儿多种疾病。后世常用于成人，每作煎剂，每为六味地黄汤。该方善治肝肾阴亏，精血不足，虚火上炎诸症，如腰痛足酸、骨热跟痛(足跟痛)、头晕、眼花、耳鸣、耳聋、遗精、咽干喉痛、潮热盗汗、五心烦热、牙齿动摇，舌红苔少，脉象细数或虚大。小儿行迟、齿迟、肢软、囟开、阴虚发热等症。现仅就个人的体会举例如下。 相似文献
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本文通过对西藏地区近五年来，１８０余例肝包囊虫病的手术配合，从而提出术中几方面的体会。首先，从术前准备到手术体位和麻醉以及术中配合的具体方法，包囊液及包囊壁的处理；术中、术后的注意事项，通过进行简单介绍，说明对特殊感染手术，应严格执行手术操作规程和无菌技术，是手术成功的先决条件；同时，也是预防交叉感染及术中意外的可靠保障。以便在今后的肝包囊虫病的手术过程中，进一步的探索，以至更加完善。 相似文献
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磁化防垢机理及适用界限研究 总被引：5，自引：0，他引：5
通过水垢的能谱分析、Ｘ射线粉晶分析和染色等实验及结晶学中的配位数理论，研究了磁化水的防垢机理及其适用界限．实验表明，水经磁化后，化学性质未变但原水垢与磁水垢的晶体结构却有明显差异．可见水的磁化处理是一种物理方法．磁化防垢效果与原水水质有关．水被加热后，只有水中的Ｃａ（ＨＣＯ３）２暂时硬度会生成具有“同质二象”特性的ＣａＣＯ３水垢，因此该水处理方法仅适用于Ｃａ盐占优势的暂硬水． 相似文献
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Marjorie Armstrong-Stassen Margaret Landstrom Ramona Lumpkin 《The Information Society》1998,14(2):153-164
This study examined how students who had no prior experience with videoconferencing would react to the use of videoconferencing as an instructional medium. Students enrolled in seven different courses completed a questionnaire at the beginning of the semester and again at the end of the semester. Students at the origination and remote sites did not differ in their reactions toward videoconferencing but there was a significant difference for gender. Women reacted less favorably to videoconferencing. Compared to the beginning of the semester, students reported significantly less positive attitudes toward taking a course through videoconferencing at the end of the semester. There were no significant differences in students' attitudes toward videoconferencing across courses at the beginning of the semester but there were significant differences across the courses at the end of the semester. The results suggest the need for better preparation for both students and instructors. 相似文献
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A joint study by Prof. ZHANG Zhibin from the CAS Institute of Zoology his co-workers from Norway US Swiss have indicated that historical outbreaks of migratory locusts in China were associated with cold spells suggesting that China's projected climate warming could decrease the pest's numbers. The study was published in Proceedings of the National Academy of Sciences on September .…… 《中国科学院院刊(英文版)》2008,22(1):6-7
Ajoint study by Prof. ZHANG Zhibin from the CAS Institute of Zoology and his co-workers from Norway, US and Swiss have indicated that historical outbreaks of migratory locusts in China were associated with cold spells, suggesting that China＇s projected climate warming could decrease the pest＇s numbers. The study was published in Proceedings of theNational Academy of Sciences on 17 September, 2007. 相似文献
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Caroline Haythornthwaite 《The Information Society》2001,17(3):211-226
A computer-mediated group is a complex entity whose members exchange many types of information via multiple means of communication in pursuit of goals specific to their environment. Over time, they coordinate technical features of media with locally enacted use to achieve a viable working arrangement. To explore this complex interaction, a case study is presented of the social networks of interactions and media use among members of a class of computer-supported distance learners. Results show how group structures associated with project teams dominated who communicated with whom, about what, and via which media over the term, and how media came to occupy their own communication niches: Webboard for diffuse class-wide communication; Internet Relay Chat more to named others but still for general communication across the class; and e-mail primarily for intrateam communication. Face-to-face interaction, occurring only during a short on-campus session, appears to have had a catalytic effect on social and emotional exchanges. Results suggest the need to structure exchanges to balance class-wide sharing of ideas with subgroup interactions that facilitate project completion, and to provide media that support these two modes of interaction. 相似文献
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《中国科学院院刊(英文版)》2008,22(1):2-3
CAS should stick to the principle of rendering service to, and giving impetus for, the development of China＇s science enterprise by making S＆T innovations, said CAS President LU Yongxiang. The CAS president made the remarks in a recent talk to communicate the gist of the winter session of the Party＇s Leading-member Group at CAS, which was held from 7 to 11 January in Beijing. 相似文献
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Electronic data interchange (EDI) provides means for interorganizational communication, creates network externalities, requires an advanced information technology (IT) infrastructure, and relies on standards. In the diffusion of such innovations, institutional involvement is imperative. Such institutions contain governmental agencies, national and global standardization organizations, local government, and nonprofit private organizations like industry associations. The last type of organizations we call intermediating institutions. They intermediate or coordinate ("inscribe") the activities of a group of would-be adopters. Unfortunately, little is known of how these organizations shape the EDI diffusion trajectory. In this article we examine one specific type of intermediating organizations?industry associations?and how they advanced the EDI diffusion process in the grocery sectors of Hong Kong, Denmark and Finland. We identify six institutional measures, placed into a matrix formed by the mode of involvement (influence vs. regulation) and the type of diffusion force (supply push vs. demand pull), that can be mobilized to further the EDI diffusion. Industry associations were found to be active users of all these measures to varying degrees. Their role was critical especially in knowledge building, knowledge deployment, and standard setting. Furthermore, institutional involvement varied due to policy and cultural contingencies and power dependencies. 相似文献
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《中国科学院院刊(英文版)》2008,22(1)
With great care, Dr. ZHOU Zhonghe takes out a package wrapped by cotton tissue from a drawer and says: "This is the gem of our collections: the fossil of a bird that lived 125 million years ago!" Then, pointing at a tiny mound, he explains: "Look, this is the claw and that is the head. It was in the egg shell and ready to hatch ... The species fell into a family of waterside inhabitants." 相似文献
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Puay Tang 《The Information Society》1998,14(1):19-31
The increasing prospects of digital piracy has prompted the perceived need by electronic publishers to adopt technical systems of protection, and governments to reform their copyright laws. This article is a preliminary study of the management of intellectual property by electronic publishers, defined as those involved in the production of online databases, and CD-ROMs. It focuses on three main issues: (1) how electronic publishers view the increasing threat of piracy; (2) the methods of protection employed to protect intellectual property in digital format; and (3) the importance of technological protection of intellectual property in electronic publications. The analysis is based on a sample of 23 UK electronic publishers. The interviews revealed an interesting assortment of protection methods and did not show that technological protection was a preferred way. Instead, the means of protection, in addition to copyright law, comprised niche markets, pricing, trust, bad publicity, and nontechnical and technical means. 相似文献
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Milton Mueller 《The Information Society》2001,17(3):151-163
Long-standing conflict between domain name registrants and trademark holders prompted the Internet Corporation for Assigned Names and Numbers (ICANN) to create a global, mandatory arbitration procedure known as the Uniform Dispute Resolution Policy (UDRP). The UDRP has been used in 2166 cases involving 3938 domain names as of 1 November 2000. The policy gives the initiator of a complaint, generally a trademark holder, the right to choose which ICANN-accredited dispute resolution service provider (RSP) will handle the case. During the preparation of the UDRP,some feared that complainant selection would lead to "forum shopping" that might bias the results. This article performs a statistical assessment of the forum-shopping thesis and finds support for it. There are statistically significant differences in the various RSPs' propensity to take away names from defendants; there are also major differences in the number of cases brought to each RSP. RSPs who take away names have the larger share of cases. The study examines other variables that might explain differences in market share, such as price, the plaintiff's nationality, or the time taken to decide a case. It finds that nationality and time also are correlated with market share. The study concludes that shopping for a favorable outcome is an important factor in the UDRP. 相似文献
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Prof. Raymond C.K. Chen a neuropsychologist with the CAS Institute of Psychology has made novel progress in his studies of schizophrenia. His work has been reported by a recent issue of Behavioural Neurology.…… 《中国科学院院刊(英文版)》2008,22(1):15-15
Prof. Raymond C.K. Chen, a neuropsychologist with the CAS Institute of Psychology, has made novel progress in his studies of schizophrenia. His work has been reported by a recent issue of Behavioural Neurology. 相似文献
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《中国科学院院刊(英文版)》2014,(3)
<正>In Xishuangbanna,one of China’s most biodiverse regions,landscape has changed dramatically during the past three decades due to the conversion of tropical rainforest to rubber plantations.In steep areas,terraces are often constructed before planting rubber trees,which causes two important changes in the soil:the destabilization of soil in the bench terraces and the increased vulnerability of unvegetated riser faces to erosion.Few studies have documented the nature and intensity of erosion on bench terraces.Prof.LIU Wenjie and his colleagues from the Xishuangbanna Tropical Botanical Garden(XTBG)conducted a study in Menglun County(21°5′39″N,101°15′55″E),Xishuangbanna to evaluate the influence 相似文献