Lipid peroxide levels and antioxidant status in alcoholic liver disease     

Seema Gupta  Rajesh Pandey  Ranjan Katyal  H. K. Aggarwal  R. P. Aggarwal  S. K. Aggarwal 《Indian journal of clinical biochemistry : IJCB》2005,20(1):67-71

The present study was conducted to evaluate some of the components of antioxidant defense system and oxidative damage in 20 male patients of alcoholic liver disease (ALD). The results were compared with 20 healthy male smokers and 20 healthy male non-smokers volunteers. Patients were subjected to detailed clinical examination and laboratory investigations. Blood samples were collected for estimating reduced glutathione (GSH), total thiols (T-SH) malondialdehyde (MDA), transaminases (AST, ALT), glutathione-S-transferease (GST) and gammaglutamyl transferase (GGT). Serum aspartate amino transferase (AST)/alanine amino transferase (ALT) ratio was significantly (p<0.01) reduced in ALD patients as compared to the controls. However, the core of utility of MDA and GST was found to be significantly (p<0.01) increased in ALD patients compared to controls. There was a significant negative correlation of MDA with both GSH and TSH. Plasma GGT levels were significantly (p<0.01) increased in alcoholics and the enzyme showed a significant positive correlation with MDA. These results give enough evidence of increased oxidative stress and compromised antioxidant defense system in patients with ALD.  相似文献   

脑科学与类脑研究概述   总被引：1，自引：0，他引：1       下载免费PDF全文

蒲慕明  徐波  谭铁牛 《中国科学院院刊》2016,31(7):725-736

脑科学和类脑智能技术是两个重要的前沿科技领域;二者相互借鉴、相互融合的发展是近年来国际科学界涌现的新趋势。脑科学研究对大脑认知神经原理的认识,提升了人类对自身的理解和脑重大疾病的诊治水平,也为发展类脑计算系统和器件、突破传统计算机架构的束缚提供了重要的依据。文章概括性地总结了国际脑科学和智能技术领域的总体进展,未来15年的发展趋势和有望解决的重大科学问题,以及我国在这两领域发展的特色和优势。  相似文献   

象山地区中国对虾白斑综合征病毒超微结构观察     

邓岳松  许梓荣  夏枚生  鲁兴萌 《科技通报》2003,19(4):327-329

从患病的中国对虾(Penaeus chinensis)头胸部分离提纯出一种杆状病毒,负染观察发现,病毒粒子的核衣壳呈杆状,大小约为(250～290) nm × (65～80) nm,每圈螺旋宽约20 nm,核衣壳的两个末端之间一般有13～15圈衣壳螺旋.个别病毒有较长的核衣壳,螺旋数达30圈,长度达到600 nm.有部分病毒核衣壳的一端有30～65 nm的凹陷.还有部分病毒核衣壳一端有30～60 nm的突出部分.  相似文献   

血浆纤维蛋白原水平升高同高血压,冠心病及卒中的联系     

袁德高  薄治仁 《科技通报》1993,9(2):108-111

选择46岁以上的高血压(HBP)、冠心病(CHD)、卒中及其它内科住院病人共140名进行了血浆纤维蛋白原(FG)、血压、甘油三酯(TG)和吸烟等因素的观察.结果表明高血压、冠心病和车中患者FG值升高,逐步回归分析看出吸烟,HBP和TG水平升高明显影响FG的含量,提示FG水平升高同HBP,CHD和年中存在着紧密的联系。  相似文献   

中国的人体组成学研究:回顾与展望          下载免费PDF全文

王自勉  李红 《体育科研》2011,32(4):42-49

人体组成学是人体生物学的分支学科之一,主要研究人体内诸多组分的含量与分布、组分之间的数量关系、在活体中测定人体组分的方法、以及体内外各种因素对组分含量的影响。研究人体组成不仅具有生物学意义,也与提高国民体质、增进健康、治疗疾病密切相关。进入21世纪以来,海峡两岸对人体组成的研究呈快速发展的态势,每年平均发表58篇论文,约占全世界此领域论文总数的3.9%。这表明两岸的人体组成学研究,已在世界上占有一席之地。中国对人体组成的研究主要集中在3个方面：对中国人群身体组成特点的研究、对运动与身体组成关系的研究、以及对疾病与身体组成关系的研究。未来,两岸的人体组成研究应该在多方位发展,特别是研究更多的身体组分（如骨骼肌与内脏脂肪组织）、应用先进的测定方法、以及探讨黄种人的身体组成特点。第9届国际人体组成学研讨会于2011年在杭州举行,这必将进一步促进海峡两岸人体组成学研究的发展。  相似文献   

田径运动消减与我国青少年体质下降的关系及对策     

肖海鹰 《湖北体育科技》2011,30(1):22-24

我国青少年体质20年持续下降是一个严重的问题,心肺血管功能差是致命的弱点,学校的应试教育是主要原因.因学生体质差怕出伤害事故而消减田径运动,因田径运动消减而造成学生心肺血管功能差,两者互为因果,形成恶性循环.将男生1 000m跑、女生800m跑直接列入中考和高考,从根本上冲破传统观念的束缚,以扭转青少年体质持续下降的状...  相似文献   

健身拳对中学生心血管系统的影响     

杨多多  任秀红  苏美华  郑锋  杨兵 《辽宁体育科技》2011,33(5):28-29,39

通过对普通中学生健身拳全套演练过程中心率和血压生理指标的动态监测,分析健身拳的运动强度和运动规律,并进行运动强度个人感觉评价指标对照,结果表明：健身拳的运动强度和运动量,符合全民健身活动的标准,中学生通过健身拳的练习对心血管系统的发育能够起到积极的促进作用,可以取得良好的健身效果。  相似文献   

Organic Acidurias: An Updated Review     

Kannan Vaidyanathan  M. P. Narayanan  D. M. Vasudevan 《Indian journal of clinical biochemistry : IJCB》2011,26(4):319-325

Organic acidurias are an important class of inherited metabolic disorders arising due to defect in intermediary metabolic pathways of carbohydrate, amino acids and fatty acid oxidation. This review summarizes the current knowledge about the important organic acidurias in the Indian population. Specifically, diagnosis and principles of treatment of organic acidurias are covered. The salient features of common organic acidurias as well as their prevalence in various parts of the world are reviewed in some detail.  相似文献   

Myeloperoxidase in Chronic Kidney Disease     

Madhusudhana Rao A  Anand U  Anand CV 《Indian journal of clinical biochemistry : IJCB》2011,26(1):28-31

Numerous lines of evidence implicate a role of myeloperoxidase (MPO) in the pathogenesis of cardiovascular disease (CVD). It is a well accepted fact that patients with chronic kidney disease (CKD) are at an increased risk for CVD. MPO is a pro-oxidant enzyme which could be involved in the increased susceptibility of these patients to CVD. Hence, the levels of plasma MPO was determined in healthy controls as well as in patients with CKD [stratified with the level of their kidney failure as CKD stages II–V (end stage renal disease)]. Plasma MPO was assayed by a spectrophotometric method. Serum urea and creatinine were estimated on a clinical chemistry analyzer using standard laboratory procedures. The mean plasma MPO levels were significantly lower with advancing stages of renal failure (P < 0.001). There was a positive correlation between MPO and GFR (r = +0.89, P < 0.001) and a negative correlation with urea (r = −0.85, P < 0.001) and creatinine (r = −0.82, P < 0.001). While an inverse association was observed between plasma MPO and urea in CKD patients, such an association was not observed in control subjects (P = 0.43). In conclusion, the decline in plasma MPO levels may be due to the inhibitory effect of uraemic toxins on the enzyme.  相似文献   

网络环境下省疾控中心图书馆工作   总被引：2，自引：0，他引：2  

张静 《中华医学图书馆杂志》2011,(10):14-15,39

网络环境下,疾控中心图书馆应围绕其职能特点提供服务,其建设目标是收集和提供信息资源、提高信息咨询能力、提供专题化信息服务和加强员工的培训,因此必须加强图书馆人才队伍建设。  相似文献