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1.
目的:探讨不同负荷运动训练对大鼠骨骼肌线粒体三羧酸循环的影响及其机制。方法:将雄性Wistar大鼠50只随机均分为5组:安静对照组(C)、低负荷运动训练组(LT)、中等负荷运动训练组(MT)、高负荷运动训练组(HT)和极高负荷运动训练组(ST),每组10只。各运动组分别进行6周的跑台运动训练。训练方案结束后,取腓肠肌样本,提取线粒体,测定线粒体柠檬酸合成酶(CS)、异柠檬酸脱氢酶(ICD)和α-酮戊二酸脱氢酶(α-KGDHC)活性;线粒体Ga2+含量、胞浆NADH、NAD+、ATP和ADP含量,以及ICD mRNA转录水平。结果:(1)不同负荷运动训练组线粒体CS、ICD和α-KGDHC的活性均显著高于安静对照组(P < 0.01),且CS和ICD活性由高到低顺序均为:MT组 > HT组 > ST组 > LT组 > C组,α-KGDHC活性由高到低顺序为:HT组 > MT组 > ST组 > LT组 > C组。(2)不同负荷运动训练组线粒体Ca2+ 含量均显著高于安静对照组(P < 0.01),其含量由高到低顺序为:MT组 > HT组 > ST组 > LT组 > C组;胞浆NADH/NAD+和ATP/ADP的比值均显著低于安静对照组(P < 0.01),其比值由低到高顺序为:MT组 < ST组 < HT组 < LT组 < C组。(3)不同负荷运动训练组ICD mRNA转录水平均高于安静对照组(P < 0.01),其水平由高到低顺序为: MT组 > HT组 > ST组 > LT组 > C组。结论:低负荷、中等负荷、高负荷及极高负荷运动训练均可提高大鼠骨骼肌线粒体三羧酸循环功能,且中等负荷运动训练效果最佳。其机制与胞浆NADH/NAD+和ATP/ADP比值、线粒体摄钙能力及限速酶基因的表达有关。 相似文献
2.
钴酸镍纳米材料具有良好的电催化氧析出反应(Oxygen Evolution Reaction,OER)活性,是一种很有发展潜力的非贵金属电催化材料。文章以碳纤维纸为基底,采用水热合成的方法对纳米结构钴酸镍的生长进行了系统的研究,分别考察了生长温度、前驱体浓度和配比、生长时间对产物的形貌、尺寸、物相结构、OER电化学性能的影响,通过对比分析后发现在生长温度100℃、生长时间5h、镍钴比为2:1时所获得的多孔片状钴酸镍纳米结构具有最佳的OER特性。 相似文献
3.
AbstractThe Program for Cooperative Cataloging (PCC) has formal relationships with the Library of Congress (LC), Share-VDE, and Linked Data for Production Phase 2 (LD4P2) for work on Bibliographic Framework (BIBFRAME), and PCC institutions have been very active in the exploration of MARC to BIBFRAME conversion processes. This article will review the involvement of PCC in the development of BIBFRAME and examine the work of LC, Share-VDE, and LD4P2 on MARC to BIBFRAME conversion. It will conclude with a discussion of areas for further exploration by the PCC leading up to the creation of PCC conversion specifications and PCC BIBFRAME data. 相似文献
4.
In this article, we report on the challenges entailed in the development of concepts, methods, and strategies for designing and implementing a cross-national research study of the first-years of school-mathematics teaching, including an exploration of how beginning mathematics teachers differ in their preparation, knowledge for teaching, teaching practice, working conditions, and pupil characteristics. The study was designed as a proof-of-concept for a study of teaching and teacher education to be implemented by educationalists, teacher educators, and early career teachers as an ongoing professional endeavor. Primary among the challenges was the development of the sampling design and the construction of measures. 相似文献
5.
桂维玲 《实验室研究与探索》2008,27(11)
用超顺磁性氧化铁制备磁共振造影剂的报道较多,其中的磁粒均为Fe3O4。本文提出了用Fe2O3的可行性,并根据超顺磁性理论推导出两种微粒显示超顺磁现象的临界尺寸理论值分别为24.8nm、31.6 nm,在1.5T磁共振磁场中的临界值为7.1 nm、11.1 nm;根据磁学理论,分析了磁共振造影剂稳定的机理;推导出在磁共振磁场中,两者在造影剂中稳定悬浮的极限尺寸为13.3 nm、14 nm。得出在造影剂中,两者既能稳定悬浮又具有超顺磁性的临界尺寸为7.1 nm、11.1 nm的结论。同时分析了两者用做磁共振胃肠造影剂的优劣点。 相似文献
6.
Frame skipping in low bit video coding could significantly reduce the visual quality of reconstructed video. At the same time, if the complexity of the video sequence remains high for a long period, then driving up the long term average bit rate, the only resort of MPEG-4 Q2 rate control algorithm results in using a high quantization scale, which shows a poor visual quality of the reconstructed video. This paper analyzes the main causes of frame skipping in current MPEG-4 frame rate control scheme, and presents a new rate control algorithm based on the quadratic R-D model over a CBR channel. Key features of the present work are. 1) the bits allocated to each P-frame or B-frame are in proportion to its distance from the end of this GOP, i.e. more bits are allocated to the frames that are nearer to their reference Ⅰ -frame: 2) the target buffer level is changeable in the GOP, at the end of each GOP( five P-frames or B-frames), the target buffer level is linearly reduced from 1/2 to 1/4 of buffer size, to other frames, the target buffer level is set to 1/2 of buffer size: 3 ) a selective and judicious use of the reduced resolution mode, in addition to a modulation of the quantization scale parameter, is to control the average long term bit rate. Experimental results with different video sequences of varied complexity, encoded at low bit rates show better efficacy of the proposed algorithm than MPEG-4 Q2 rate control scheme, and the experimental results also show that the improved algorithm has significantly reduced the number of frame skipping, increased the overall PSNR, and improved the perceptual quality. 相似文献
7.
The success of test reform relies considerably on how stakeholders understand and accept the revised test (Green & Andrade, 2010). This study provided an opportunity for students and teachers to share their perceptions of a recently revised English test in China, the Test for English Majors Grade Four (TEM4). In addition, this study examined how stakeholders’ perceptions of the test varied across institutions of different academic rankings. Survey data were collected from 496 students and 79 teachers, of whom 32 students and 12 teachers participated in a post-survey interview. Findings indicate that although stakeholders were overall positive about the revised TEM4, their perceptions were qualified by concerns with content representation and test difficulty. In addition, the data suggest that the revised TEM4 was associated with context-varying washback effects and negative psychological impacts. These findings highlight the important contribution that students' and teachers' perceptions may have in the test reform process. 相似文献
8.
李海斌张晓波石林爽张曼婷 《福建工程学院学报》2021,(4):360-364
采用固体渗剂包埋渗法对Ti-6Al-4V钛合金进行硼-稀土共渗处理,并利用超声振动空蚀机研究分析试样在去离子水中的空蚀性能。结果表明,硼-稀土共渗在Ti-6Al-4V合金表面获得均匀致密的表面渗层。表面渗层具有很高的显微硬度,与基体冶金结合,其主要由TiB2、TiB化合物层和B原子固溶于α-Ti的扩散层构成。稀土元素La的添加,提高渗硼效率,使试样表面渗层厚度增加,显微硬度显著提高,材料的抗空蚀性能得到显著改善。 相似文献
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10.
红色基因是中华优秀传统文化的精神财富,是社会主义核心价值观的组成部分.高校思想政治理论课是落实高校立德树人根本任务的关键课程,也是传承红色基因的主渠道和主阵地.通过分析红色基因传承在高校思想政治教育工作中的价值,探究如何将红色基因传承与高校思政课有效融合,进一步提升育人效果. 相似文献