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1.
BackgroundAngiogenesis constitutes a major mechanism responsible for exercise-induced beneficial effects. Our previous study identified a cluster of differentially expressed extracellular vesicle microRNAs (miRNAs) after exercise and found that some of them act as exerkines. However, whether these extracellular vesicle miRNAs mediate the exercise-induced angiogenesis remains unknown.MethodsA 9-day treadmill training was used as an exercise model in C57BL/6 mice. Liver-specific adeno-associated virus 8 was used to knock down microRNA-122-5p (miR-122-5p). Human umbilical vein endothelial cells were used in vitro.ResultsAmong these differentially expressed extracellular vesicle miRNAs, miR-122-5p was identified as a potent pro-angiogenic factor that activated vascular endothelial growth factor signaling and promoted angiogenesis both in vivo and in vitro. Exercise increased circulating levels of miR-122-5p, which was produced mainly by the liver and shuttled by extracellular vesicles in mice. Inhibition of circulating miR-122-5p or liver-specific knockdown of miR-122-5p significantly abolished the exercise-induced pro-angiogenic effect in skeletal muscles, and exercise-improved muscle performance in mice. Mechanistically, miR-122-5p promoted angiogenesis through shifting substrate preference to fatty acids in endothelial cells, and miR-122-5p upregulated endothelial cell fatty-acid utilization by targeting 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT1). In addition, miR-122-5p increased capillary density in perilesional skin tissues and accelerated wound healing in mice.ConclusionThese findings demonstrated that exercise promotes angiogenesis through upregulation of liver-derived extracellular vesicle miR-122-5p, which enhances fatty acid utilization by targeting AGPAT1 in endothelial cells, highlighting the therapeutic potential of miR-122-5p in tissue repair.  相似文献   

2.
BackgroundRecognizing sport-related concussion (SRC) is challenging and relies heavily on subjective symptom reports. An objective, biological marker could improve recognition and understanding of SRC. There is emerging evidence that salivary micro-ribonucleic acids (miRNAs) may serve as biomarkers of concussion; however, it remains unclear whether concussion-related miRNAs are impacted by exercise. We sought to determine whether 40 miRNAs previously implicated in concussion pathophysiology were affected by participation in a variety of contact and non-contact sports. Our goal was to refine a miRNA-based tool capable of identifying athletes with SRC without the confounding effects of exercise.MethodsThis case-control study harmonized data from concussed and non-concussed athletes recruited across 10 sites. Levels of salivary miRNAs within 455 samples from 314 individuals were measured with RNA sequencing. Within-subjects testing was used to identify and exclude miRNAs that changed with either (a) a single episode of exercise (166 samples from 83 individuals) or (b) season-long participation in contact sports (212 samples from 106 individuals). The miRNAs that were not impacted by exercise were interrogated for SRC diagnostic utility using logistic regression (172 samples from 75 concussed and 97 non-concussed individuals).ResultsTwo miRNAs (miR-532-5p and miR-182-5p) decreased (adjusted p < 0.05) after a single episode of exercise, and 1 miRNA (miR-4510) increased only after contact sports participation. Twenty-three miRNAs changed at the end of a contact sports season. Two of these miRNAs (miR-26b-3p and miR-29c-3p) were associated (R > 0.50; adjusted p < 0.05) with the number of head impacts sustained in a single football practice. Among the 15 miRNAs not confounded by exercise or season-long contact sports participation, 11 demonstrated a significant difference (adjusted p < 0.05) between concussed and non-concussed participants, and 6 displayed moderate ability (area under curve > 0.70) to identify concussion. A single ratio (miR-27a-5p/miR-30a-3p) displayed the highest accuracy (AUC = 0.810, sensitivity = 82.4%, specificity = 73.3%) for differentiating concussed and non-concussed participants. Accuracy did not differ between participants with SRC and non-SRC (z = 0.5, p = 0.60).ConclusionSalivary miRNA levels may accurately identify SRC when not confounded by exercise. Refinement of this approach in a large cohort of athletes could eventually lead to a non-invasive, sideline adjunct for SRC assessment.  相似文献   

3.
Purpose: To compare characteristics of club level male soccer players 11 and 13 years of age, and to evaluate playing status in soccer two and 10 years after baseline by birth quarter (BQ).

Methods: Youth players 11 (n = 62, born 1992, observed December 2003) and 13 (n = 50, born 1990, observed April 2004) years were grouped by BQ. Baseline data included stature, weight, maturity status, functional capacities, soccer skills, goal orientation, and coach evaluation of potential. Playing status in soccer in 2006 and 2014 was also available. Baseline characteristics and subsequent playing status were compared by BQ.

Results: Baseline characteristics did not differ by BQ except for age and percentage of predicted adult height. Though not significant, coaches tended to rate players in BQ1as higher in potential. For those competing in soccer as adults, BQ2 (4), BQ3 (5) and BQ4 (2) were represented among players11 years, and BQ1 (3), BQ2 (2), BQ3 (1) and BQ4 (4) among players 13 years.

Conclusion: Although limited to small numbers, differences among players by BQ were inconsistent. The results indicate a need to extend potential explanations of the RAE to include behavioral variables, coaches, training environment, and perhaps the culture of the sport.  相似文献   


4.
ABSTRACT

The physical demands of English Premier League soccer goalkeepers were quantified during training and match-play in a two-part study. Goalkeeper-specific micromechanical electrical systems (MEMS) devices, profiled training and match-day activities throughout one competitive week (n=8; part A). Changes in MEMS-derived outputs were also profiled throughout match-play (100 matches; n=8, 18±14 observations per goalkeeper; part B). In part A, goalkeeping-training elicited the most dives (51±11) versus all activities (all p≤0.030) except shooting-training (p=0.069). Small-sided games elicited the fewest (5±3) dives (all p≤0.012). High-speed distance covered in match (103±72 m) was similar to goalkeeping-training (p=0.484), while exceeding shooting-training, small-sided games, pre-match shooting, and pre-match warm-up (all p=0.012). Most changes of direction (34±12) and explosive efforts (70±18) occurred during goalkeeping-training, with values exceeding match (both p=0.012). In part B, between-half reductions in total distance, but increased high-speed changes of direction and explosive efforts, occurred (both p≤0.05). Excluding the number of high jumps, all variables differed from 0-15-min during at least one match epoch, with more dives (1.3±1.4 vs 1.0±1.1) and explosive efforts (2.5±2.4 vs 2.0±1.8) performed between 75-90-min versus 0-15-min (all p<0.05). These data highlight the differing physical demands of various activities performed by professional soccer goalkeepers throughout a competitive week.  相似文献   

5.
ABSTRACT

This study aimed to examine the effects of two jump squat (JS) training programs involving different loading ranges in under-20 soccer players during a preseason period. Twenty-three elite young soccer players performed sprint speed (at 5-, 10-, and 20-m), change-of-direction (COD) speed, JS peak-power (PP), and countermovement jump (CMJ) tests pre and post four weeks of training. Athletes were pair-matched in two groups according to their optimum power loads (OPL) as follows: lower than OPL (LOPL; athletes who trained at a load 20% lower than the OPL) and higher than OPL (HOPL; athletes who trained at a load 20% higher than the OPL). Magnitude-based inferences were used to compare pre- and post-training measures. Meaningful increases in the PP JS were observed for both groups. Likely and possible improvements were observed in the 5- and 10-m sprint velocity in the LOPL group. Meanwhile, possible and likely improvements were observed in the CMJ, 5- and 10-m sprint velocity, and COD speed in the HOPL group. Overall, both training schemes induced positive changes in athletic performance. Soccer coaches and sport scientists can implement the JS OPL-based training schemes presented here, either separately or combined, to improve the physical performance of youth soccer players.  相似文献   

6.
ABSTRACT

Purpose: This study examined the relationships between the Yo-Yo Intermittent Recovery Test level 1 (Yo-Yo IR1) and resting heart rate variability (HRV) and submaximal 5?-5? test derived measures in novice male soccer players. Methods: Forty players (11.54 ± 0.58 years) from a soccer academy participated in this study, performing physical tests on two different days, separated by 48 h, as follows: (day 1) resting HRV and Yo-Yo IR1 test, and (day 2) anthropometric assessments (for peak height velocity assessment [PHV]) and the 5?-5? test. The Pearson product-moment correlation coefficient was used to determine the correlations between Yo-Yo IR1 performance and the remaining variables. A partial correlation analysis was further performed using age, stature, body mass, distance to PHV, and age at PHV as “confounders.” Results: The highest correlation score was observed between Yo-Yo IR1 performance and resting HRV, when the absolute age was used as confounder (r = 0.72; p < .05). Conclusions: We observed that a practical measure of parasympathetic activity at rest is largely associated with performance obtained during a traditional intermittent endurance performance test.  相似文献   

7.
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8.
Abstract

The present study investigated the heart rate (HR) response to various types of physical education (PE) activities for 8- to 9-year-olds (five school classes, n = 93) and the fitness effects of a short-term PE training programme (three of the five classes, n = 59) with high compared to low-to-moderate aerobic intensity. HR was recorded during small-sided indoor soccer (SO), basketball (BB), unihockey (UH), circuit training (CT), walking (W) and Nintendo Wii Boxing (NWB) and Nintendo Wii Tennis (NWT). Maximal HR (HRmax) and physical fitness was determined by the Yo-Yo Intermittent Recovery Level 1 Children's test (YYIR1C) test. Following cluster randomisation, three classes were tested before and after 6 wks with 2 × 30 min/wk SO and UH lessons [high-intensity (HI), 2 classes, n = 39] or low-to-moderate intensity PE lessons (CON, 1 class, n = 20). Average HR in SO (76 ± 1% HRmax), BA (77 ± 1% HRmax) and UH (74 ± 1% HRmax) was higher (P < 0.05) than in CT (62 ± 1% HRmax), W (57 ± 1% HRmax), NWB (65 ± 2% HRmax) and NWT (57 ± 1% HRmax). Time with HR > 80% and 90% HRmax, respectively, was higher (P < 0.05) in SO (42 ± 4 and 12 ± 2%), BB (41 ± 5 and 13 ± 3%) and UH (34 ± 3 and 9 ± 2%) than in CT, W and NW (0–5%), with time >80% HRmax being higher (P < 0.05) in SO than UH. After 6 wk, YYIR1C performance was increased (P < 0.05) by 22% in HI (673 ± 57 to 821 ± 71 m), but unaltered in CON (674 ± 88 to 568 ± 81 m). HR 2 min into YYIR1C was lowered (P < 0.05) in HI after 6 wks (92.4 ± 0.8 to 89.1 ± 0.9% HRmax), but not in CON. In conclusion, ball games elicited high aerobic loading for young schoolchildren and a short-term, low-volume ball game PE-intervention improved physical fitness. Traditional PE sessions had no effects on intermittent exercise performance.  相似文献   

9.
ABSTRACT

The speed performance is involved not only in linear sprints, but also in a wide spectrum of multi-directional movements, such as curve sprinting. Curved sprint can be defined as sprint with gradual and continuous change of direction (COD). Although ~85% of the actions performed at maximum velocity in a professional soccer league are curvilinear sprints, there is not any specific test to assess this ability. This study aimed to analyse the reliability of a new curve sprint test, and compare its results with those obtained by soccer players in linear sprint. Forty experienced soccer players performed 3 attempts of curve sprint (using the penalty arc) to right and left side (17 m), and 3 linear sprints (17 m) in two different days. The ICCs (inter-session reliability) were 0.93 for sprint curve right side (CSRS) and 0.89 for sprint curve left side (CSLS), considered “acceptable”. The CVs (intra-session reliability) were 0.87% in CSRS and 1.15% in CSLS. The coefficient of determination (R2) between linear and curve sprinting was ~35%. The association between curve sides was “very large” (r = 0.878; p < 0.01). In summary, we showed that “curve sprint test” is highly reliable, and that curvilinear and linear sprints are different and independent actions.  相似文献   

10.
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11.
Purpose: Acute muscle damage after exercise triggers subsequent regeneration, leading to hypertrophy and increased strength after repeated exercise. It has been debated whether acute exercise-induced muscle damage is altered under various premenopausal estrogen conditions. Acute contraction-induced muscle damage was compared during exogenous (oral contraceptive, OC), endogenous (luteal phase, HI), or low (menses, LO) estrogen in healthy young women aged 21 to 30 years old. Methods: Women (OC, n = 9; HI, n = 9; LO, n = 8; total N = 26) performed 1 neuromuscular electrical stimulation (NMES) bout. Soreness, measured via visual analog scale and the Likert Scale of Muscle Soreness for Lower Limb (LSMSLL), quadriceps strength, and plasma myoglobin (Mb), interleukin (IL)-6, IL-8, and granulocyte-colony stimulating factor were measured before and after NMES. Results: NMES performance was similar across groups. Meaningful within-group increases in Mb (effect size [ES] = 1.12) and IL-8 (ES = 0.38) occurred in LO; ES for HI and OC were trivial. ES of the between-group difference in change was moderate for Mb (LO vs. HI = 1.15) and IL-8 (LO vs. HI = 0.86; LO vs. OC = 0.73). 17-β estradiol correlated moderately and negatively with Mb relative change (r = –.52, p < .05). LO had ~5% greater strength loss than OC and HI. The mean change score for the LSMSLL 2 days post-NMES was clinically greater in LO than OC or HI. Conclusions: Acute NMES-induced indicators of muscle fiber damage and qualitative muscle soreness may be attenuated during the luteal phase or active OC pill consumption compared with the menstrual phase.  相似文献   

12.
BackgroudBlood flow restriction (BFR) with low-intensity resistance training has been shown to result in hypertrophy of skeletal muscle. In this study, we tested the hypothesis that BFR during the rest periods between acute, high-intensity resistance exercise sessions (70% of 1 repetition maximum, 7 sets with 10 repetitions) enhances the effects of the resistance training.MethodsA total of 7 healthy young men performed squats, and between sets BFR was carried out on one leg while the other leg served as a control. Because BFR was applied during rest periods, even severe occlusion pressure (approximately 230 mmHg), which almost completely blocked blood flow, was well-tolerated by the participants. Five muscle-specific microRNAs were measured from the biopsy samples, which were taken 2 h after the acute training.ResultsDoppler data showed that the pattern of blood flow recovery changed significantly between the first and last BFR. microRNA-206 levels significantly decreased in the BFR leg compared to the control. The mRNA levels of RAC-β serine/threonine-protein kinase v22, nuclear respiratory factor 1, vascular endothelial growth factor, lupus Ku autoantigen protein p70 genes (p < 0.05), and paired box 7 (p < 0.01) increased in the BFR leg. The protein levels of paired box 7, nuclear respiratory factor 1, and peroxisome proliferator-activated receptor γ coactivator 1α did not differ between the BFR leg and the control leg.ConclusionBFR, during the rest periods of high-load resistance training, could lead to mRNA elevation of those proteins that regulate angiogenesis, mitochondrial biogenesis, and muscle hypertrophy and repair. However, BFR also can cause DNA damage, judging from the increase in mRNA levels of lupus Ku autoantigen protein p70.  相似文献   

13.
Abstract

The aim of this study was to evaluate the effect of a soccer-training season on the anthropometric and performance characteristics of elite youth soccer players.

Two groups (age: 14.4 years) participated in this study: 1) 24 soccer players training 8 to 10 hours per week and 2) 26 non-athletic boys used as controls. Anthropometric measurements, aerobic (Yo-Yo Intermittent Recovery test level 1) and anaerobic (counter-movement-jump (CMJ), squat-jump (SqJ), five-jump-test (5JT), and speed (T5m, 10 m, 30 m)) performances were assessed twice during 8 months (T0: October; T1: May) of the competitive season.

Data showed significant differences in height and weight at T0 between the two groups (P < 0.05), while no difference in the percentage of body fat (%BF) was observed. However, the soccer players were significantly taller and had lower %BF than age-matched controls at T1.

Compared to the controls, the soccer players attained better results in the physical fitness test (P < 0.05) at T0 and T1 except in (T5m) sprinting speed. Hence, significant improvements (P < 0.05) in physical parameters were observed between T0 and T1 only in soccer players.

The results demonstrate that soccer-training season was able to provide maturation free improvement in anthropometric and performance characteristics in young soccer players during the training season.  相似文献   

14.

In the current study, we examined the relationship between serum creatine kinase (CK) activity following upper body resistance exercise with a 1- or 3-min rest between sets. Twenty men performed two sessions, each consisting of four sets with a 10-repetition maximum load. The results demonstrated significantly greater volume for the 3-min condition (M = 4,156 kg, SD = 867, for 3 min; vs. M = 3,503 kg, SD = 759, for 1 min; p < .001), with no significant differences in delta CK activity between conditions (p = .574). Nevertheless, there was a weak correlation between the delta CK activity and total volume of exercise completed (r = .55 with a 1-min rest, and r =.45 with a 3-min rest). Therefore, the volume following upper body resistance exercise correlates weakly with serum CK levels, irrespective of rest interval length between sets.  相似文献   

15.
Purpose: The powerful activity profile of elite soccer match play has not been documented appropriately to inform specific maximal power assessment and development criteria. The aims of the current study were to develop a reliable soccer-specific powerful action (SSPA) notational analysis coding system that could be used to compare frequency and durations of powerful actions during elite youth soccer match play. Methods: Sixteen elite male English Premier League (EPL) Academy players (19 ± 1 yrs) were recorded by an individual camera during 16 competitive EPL U18 and U21 games. Video footage was analyzed using performance analysis software and SSPAs were coded according to the following categories: initial acceleration, leading acceleration, sprint, unilateral jump and bilateral jump. Results: The SSPA coding system demonstrated very good inter- and intra-rater reliability (kappa coefficients ≥ 0.827). Elite youth EPL soccer players undertook significantly more initial (31 ± 9) and leading (37 ± 12) accelerations than sprints (8 ± 3; p = .014, d = 1.7, and p < .001, d = 1.7, respectively) and jumps (6 ± 5; p = .002, d = 1.7 and p < .001, d = 1.7, respectively). Players performed a significantly greater number of initial and leading accelerations with action durations below 1.5 s compared to above 1.5 s (p = .001, d = 1.6, and p = .002, d = 1.4), respectively. Conclusions: Our SSPA coding system provides a reliable observational instrument for quantifying the frequency and duration of powerful actions performed during elite soccer match play. In our sample of elite youth soccer players, horizontal accelerations of short duration (< 1.5 s) from different starting speeds appear the most dominant powerful action in elite youth soccer match play.  相似文献   

16.
To determine the movement patterns and physiological demands of top-class soccer assistant referees, we performed computerized time-motion analysis and measured heart rate and blood lactate concentration in 15 assistant referees during 22 competitive matches in the top Danish league. To relate match performance to the physical capability of the assistant referees, they performed a 3 x 30 m sprint protocol before and after matches and a laboratory treadmill test within 3 weeks of the games. The mean total distance covered by the top-class assistant referees was 7.28 (range 5.78-8.16) km, of which 1.15 (0.86-1.44) km was high-intensity running and 1.16 (0.12-2.34) km was sideways running. The amount of high-intensity running during a game was correlated with performance of repeated sprints (r = 0.80, P < 0.05). Mean heart rate was 137 (117-159) beats x min(-1), corresponding to 73% (60-88%) of maximal heart rate and 65% (53-80%) of maximal oxygen uptake. Blood lactate concentration was 4.7 (1.6-11.0) and 4.8 (1.1-13.7) mmol x 1(-1) after the first and second half, respectively. Sprinting performance was poorer (P < 0.05) after than before the games. The peak distance to the offside line was greater (P < 0.05) in the second than the first half (7 +/- 1 vs 5 +/- 0 m). Our results show that: (1) top-class assistant soccer refereeing is characterized by brief intense bouts of forward and sideways running interspersed with long periods of low activity; (2) top-class soccer assistant referees have moderate aerobic energy production during games with episodes of high aerobic and anaerobic energy turnover; (3) assistant referees' performance of repeated sprints correlates with the amount of high-intensity running performed in a game; and (4) sprint performance decreases towards the end of a game, which appears to affect assistant referees' ability to keep up with play.  相似文献   

17.
Abstract

Poor neuromuscular control and fatigue have been proposed as a risk factor for non-contact injuries especially around peak height velocity (PHV). This study explored the effects of competitive soccer match-play on neuromuscular performance and muscle damage in male youth soccer players. 24 youth players aged 13-16y were split into a PHV group (?0.5 to 0.5y) and post PHV group (1.0–2.5y) based on maturity off-set. Leg stiffness, reactive strength index (RSI), muscle activation, creatine kinase (CK), and muscle soreness were determined pre and post a competitive soccer match. Paired t-tests were used to explore differences pre and post competitive match play and independent sample t-tests for between groups differences for all outcome measures. There was no significant fatigue-related change in absolute and relative leg stiffness or muscle activation in both groups, except for the gastrocnemius in the post PHV group. RSI, CK and perceived muscle soreness were significantly different after soccer match-play in both groups with small to large effects observed (ES:0.41–2.82). There were no significant differences between the groups pre match-play except for absolute and relative leg stiffness (P?<?0.001; ES?=?1.16 and 0.63 respectively). No significant differences were observed in the fatigue related responses to competitive match play between groups except for perceived muscle soreness. The influence of competitive match-play on neuromuscular function and muscle damage is similar in male youth around the time of PHV and those post-PHV indicating that other factors must contribute to the heightened injury risk around PHV.  相似文献   

18.
PurposeThis study aimed to assess the effectiveness and time course for improvements in explosive actions through resistance training (RT) vs. plyometric training (PT) in prepubertal soccer players.MethodsThirty-four male subjects were assigned to: a control group (n = 11); an RT group (5 regular soccer training sessions per week, n = 12); a PT group (3 soccer training sessions and 2 RT sessions per week, n = 11). The outcome measures included tests for the assessment of muscle strength (e.g., 1 repetition maximum half-squat test), jump ability (e.g., countermovement jump, squat jump, standing long jump, and multiple 5 bounds test), linear speed (e.g., 20 m sprint test), and change of direction (e.g., Illinois change of direction test).ResultsThe RTG showed an improvement in the half-squat (Δ = 13.2%; d = 1.3, p < 0.001) and countermovement jump (Δ = 9.4%; d = 2.4, p < 0.001) at Week 4, whereas improvements in the 20-m sprint (Δ = 4.2%; d = 1.1, p < 0.01); change of direction (CoD) (Δ = 3.8%; d = 2.1, p < 0.01); multiple 5 bounds (Δ = 5.1%; d = 1.5, p < 0.05); standing long jump (Δ = 7.2%; d = 1.2, p < 0.01); squat jump (Δ = 19.6%; d = 1.5, p < 0.01); were evident at Week 8. The PTG showed improvements in CoD (Δ = 2.1%; d = 1.3, p < 0.05); standing long jump (Δ = 9.3%; d = 1.1, p < 0.01); countermovement jump (Δ = 16.1%; d = 1.2, p < 0.01); and squat jump (Δ = 16.7%; d = 1.4, p < 0.01); at Week 8 whereas improvements in the 20-m sprint (Δ = 4.1%; d = 1.3, p < 0.01); and multiple 5 bounds (Δ = 7.4%; d = 2.4, p < 0.001); were evident only after Week. The RT and PT groups showed improvements in all sprint, CoD, and jump tests (p < 0.05) and in half-squat performance, for which improvement was only shown within the RTG (p < 0.001).ConclusionRT and PT conducted in combination with regular soccer training are safe and feasible interventions for prepubertal soccer players. In addition, these interventions were shown to be effective training tools to improve explosive actions with different time courses of improvements, which manifested earlier in the RTG than in the PTG. These outcomes may help coaches and fitness trainers set out clear and concise goals of training according to the specific time course of improvement difference between RT and PT on proxies of athletic performance of prepubertal soccer players.  相似文献   

19.
ABSTRACT

The objective of this study was to analyse the effect of the use of social networks in smartphones or playing video games on the passing decision-making performance in professional soccer athletes. Participants were 25 male professional soccer athletes (mean ± SD: age 23.4 ± 2.8 years). The participants performed three randomised conditions divided into three groups: control (CON), smartphone (SMA), and video game (VID). Before and after each experimental condition, the Stroop Task assessed the level of induced mental fatigue. Then, the athletes performed a simulated soccer match. A CANON® camera recorded the matches for further analysis on passing decision-making performance. A group effect was identified (p < .01) with impairment on passing decision-making performance for the SMA (p = .01, ES = 0.5) and VID (p = .01, ES = 0.5) conditions. We concluded that the use of social networks on smartphones and/or playing video games right before official soccer matches might impair the passing decision-making performance in professional soccer athletes.  相似文献   

20.
急性低氧暴露对足球运动员甲襞微循环的影响   总被引：1，自引：0，他引：1  
目的观察急性低氧暴露对足球运动员甲襞微循环的影响及探讨可能的机制。方法让8名北京体育大学体育系男子足球专项运动员晚上在低氧房暴露居住10 h。低氧房中氧含量为15.3%(相当于海拨2500 m)。分别于低氧暴露前1天、急性低氧暴露10 h后测试安静时和定量运动负荷后甲襞微循环的变化。结果急性低氧暴露后,(1)安静时形态积分较高,运动后10 min、15 min的形态积分均比安静时明显降低(P<0.05);(2)运动后即刻的流态积分、总积分均显著高于安静时(P<0.05);(3)运动后5 min、10 min及15 min时,血流速逐渐加快,红细胞聚集程度减轻,积分值降低(P<0.05)。结论急性低氧暴露后,甲襞微循环出现明显的代偿性变化。  相似文献   

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