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1.
由清华大学-中科院生物物理所结构生物学联合研究小组完成的"线粒体呼吸链膜蛋白复合物Ⅱ的晶体结构"研究成果以Article的方式发表在2005年7月1日出版的Cell上.本文介绍了该项成果的研究背景、意义、主要创新点及方法.  相似文献   

2.
《中国科学院院刊》2014,(4):517-518
中科院生物物理所黄亿华研究组对细菌脂多糖转运组装膜蛋白复合体结构解析取得重要成果。研究人员成功地解析了致病菌福氏志贺菌来源的分子量约为110000D的LptD—LptE膜蛋白复合体2.4A的高分辨率晶体结构。该晶体结构披露了一种前所未有的由两个蛋白所形成的“塞子-桶”结构模式,并首次观察到一个整合膜蛋白(LptD)中含有两对非连续的、跨结构域的二硫键。  相似文献   

3.
针对不同反应条件对免疫沉淀分离膜蛋白的影响进行了研究。  相似文献   

4.
蓝绿温和胶电泳(BN-PAGE)以其温和、高效的优势,越来越多的被应用于植物研究领域。而类囊体作为植物光合作用的重要场所,在植物蛋白质组学研究中倍受关注。着重介绍了BN-PAGE在植物类囊体蛋白组学研究方面的应用,同时对BN-PAGE在此领域的应用趋势进行了探讨。  相似文献   

5.
膜脂-膜蛋白相互作用研究及其在医学和农业上的应用   总被引:2,自引:1,他引:2  
膜脂-膜蛋白相互作用是生物膜研究的中心环节。我们分别从线粒体膜、支原体膜、叶绿体膜、红细胞膜及人工膜研究这一重要问题,并联系农业、医学实际研究植物抗冷性和细胞衰老的分子机制。通过五年的工作,发现膜脂能影响和调节线粒体H~+-ATP酶、莱氏衣原体ATP酶和叶绿体捕光色素复合体构象及活性,非双层脂、非双层脂结构对膜蛋白功能有明显影响,提出鉴定水稻抗冷性的有效指标,筛选出水稻育秧抗寒剂及中药抗衰老药物。  相似文献   

6.
由生物物理研究所主持,植物研究所参加完成的"菠菜主要捕光复合物的晶体结构"研究成果以Article的方式发表在2004年3月18日出版的Nature上,该晶体结构图被选作本期杂志的封面图案.本文介绍了该项成果的研究背景、意义、主要创新点及方法.  相似文献   

7.
细胞分泌是基本的生命活动,是生物信息传递的关键环节.免疫防卫反应、细胞的生长、受精过程、细胞内外的物质交换、细胞膜上受体蛋白的嵌入以及再循环等细胞生理功能的实现都与细胞分泌活动有关,且所涉及的一些膜转运蛋白和分子机制是类似的.文章对分泌过程、相关蛋白质的功能以及对分泌的调控等进行了概述,介绍了国内外对膜蛋白转运机制及其相关蛋白质功能的最新研究成果.并对目前提出的假设及存在的问题进行了讨论与展望.  相似文献   

8.
首先对磁性材料中磁结构、磁畴结构和拓扑磁结构之间的联系进行深入的分析。第一,磁畴结构由材料的磁结构、内禀磁性和微结构因素等内容构成;第二,磁畴结构对材料磁化和退磁化过程以及技术磁性造成了重要的影响。拓扑学与材料物理、材料性能之间的关系较为紧密。通过研究发现,大多数学者的研究内容主要集中在拓扑磁性组态,如涡旋、磁泡、麦纫、斯格米子等。研究发现这些拓扑磁结构的拓扑性质与磁性能联系紧密。  相似文献   

9.
本文对三尖杉属中三种植物即:三尖杉Cephalotaxus fortunei,粗榧C.sinensis 和柱   冠日本粗榧C.harringtonia cv.Fastigiata越冬期的光合器功能进行了研究。研究结果表明   这三种常绿三尖杉植物越冬时叶绿体的光合放氧活性受到抑制,但光系统II中心的活性和镁   离子调节光能分配的功能存在。说明其越冬特性与松柏科植物类似。     叶绿体膜的低温荧光测定结果表明三种植物的F685,F695和F735的比率各不相同。用SDS—   聚丙烯酰胺凝胶电泳分析叶绿体膜蛋白,发现柱冠日本粗榧的多肽数与三尖杉和粗榧有明显差异。以上特征可能有助于分类或系统位置的研究。  相似文献   

10.
以多种经济学和管理学理论的观点作为研究基础,采取以理论论证为主、理论与联系实际分析研究为辅的方法,最后得出资本结构和治理结构的目标一致性,即价值最大化的结论.  相似文献   

11.
Aresearch group led by Prof. ZHAI Qiwei from the Institute for Nutritional Sciences under the CAS Shanghai Institutes for Biological Sciences has discovered that even relatively low doses of resveratrol--a chemical found in the skins of red grapes and in red wine--can improve the sensitivity of mice to the hormone insulin, according to a report in the October,2007 issue of Cell Metabolism. As insulin resistance is often characterized as the most critical factor contributing to the development of Type 2 diabetes, the findings“provide a potential new therapeutic approach for preventing or treating” both conditions, the researchers said.  相似文献   

12.
This study examined how students who had no prior experience with videoconferencing would react to the use of videoconferencing as an instructional medium. Students enrolled in seven different courses completed a questionnaire at the beginning of the semester and again at the end of the semester. Students at the origination and remote sites did not differ in their reactions toward videoconferencing but there was a significant difference for gender. Women reacted less favorably to videoconferencing. Compared to the beginning of the semester, students reported significantly less positive attitudes toward taking a course through videoconferencing at the end of the semester. There were no significant differences in students' attitudes toward videoconferencing across courses at the beginning of the semester but there were significant differences across the courses at the end of the semester. The results suggest the need for better preparation for both students and instructors.  相似文献   

13.
Ajoint study by Prof. ZHANG Zhibin from the CAS Institute of Zoology and his co-workers from Norway, US and Swiss have indicated that historical outbreaks of migratory locusts in China were associated with cold spells, suggesting that China's projected climate warming could decrease the pest's numbers. The study was published in Proceedings of theNational Academy of Sciences on 17 September, 2007.  相似文献   

14.
A computer-mediated group is a complex entity whose members exchange many types of information via multiple means of communication in pursuit of goals specific to their environment. Over time, they coordinate technical features of media with locally enacted use to achieve a viable working arrangement. To explore this complex interaction, a case study is presented of the social networks of interactions and media use among members of a class of computer-supported distance learners. Results show how group structures associated with project teams dominated who communicated with whom, about what, and via which media over the term, and how media came to occupy their own communication niches: Webboard for diffuse class-wide communication; Internet Relay Chat more to named others but still for general communication across the class; and e-mail primarily for intrateam communication. Face-to-face interaction, occurring only during a short on-campus session, appears to have had a catalytic effect on social and emotional exchanges. Results suggest the need to structure exchanges to balance class-wide sharing of ideas with subgroup interactions that facilitate project completion, and to provide media that support these two modes of interaction.  相似文献   

15.
Active biological molecules and functional structures can be fabricated into a bio-mimetic system by using molecular assembly method. Such materials can be used for the drug delivery, disease diagnosis and therapy, and new nanodevice construction.  相似文献   

16.
CAS should stick to the principle of rendering service to, and giving impetus for, the development of China's science enterprise by making S&T innovations, said CAS President LU Yongxiang. The CAS president made the remarks in a recent talk to communicate the gist of the winter session of the Party's Leading-member Group at CAS, which was held from 7 to 11 January in Beijing.  相似文献   

17.
With great care, Dr. ZHOU Zhonghe takes out a package wrapped by cotton tissue from a drawer and says: "This is the gem of our collections: the fossil of a bird that lived 125 million years ago!" Then, pointing at a tiny mound, he explains: "Look, this is the claw and that is the head. It was in the egg shell and ready to hatch ... The species fell into a family of waterside inhabitants."  相似文献   

18.
Electronic data interchange (EDI) provides means for interorganizational communication, creates network externalities, requires an advanced information technology (IT) infrastructure, and relies on standards. In the diffusion of such innovations, institutional involvement is imperative. Such institutions contain governmental agencies, national and global standardization organizations, local government, and nonprofit private organizations like industry associations. The last type of organizations we call intermediating institutions. They intermediate or coordinate ("inscribe") the activities of a group of would-be adopters. Unfortunately, little is known of how these organizations shape the EDI diffusion trajectory. In this article we examine one specific type of intermediating organizations?industry associations?and how they advanced the EDI diffusion process in the grocery sectors of Hong Kong, Denmark and Finland. We identify six institutional measures, placed into a matrix formed by the mode of involvement (influence vs. regulation) and the type of diffusion force (supply push vs. demand pull), that can be mobilized to further the EDI diffusion. Industry associations were found to be active users of all these measures to varying degrees. Their role was critical especially in knowledge building, knowledge deployment, and standard setting. Furthermore, institutional involvement varied due to policy and cultural contingencies and power dependencies.  相似文献   

19.
This essay focuses on universal service and the Internet as means to support social and political participation. The emphasis on access to telecommunications systems in conventional approaches to universal service is contrasted with access to content. A model of the information environment is described that accounts for the roles of content and conduit, both of which are necessary conditions to achieve true access. A method is outlined for employing information indicators to observe or measure the information environment.  相似文献   

20.
The increasing prospects of digital piracy has prompted the perceived need by electronic publishers to adopt technical systems of protection, and governments to reform their copyright laws. This article is a preliminary study of the management of intellectual property by electronic publishers, defined as those involved in the production of online databases, and CD-ROMs. It focuses on three main issues: (1) how electronic publishers view the increasing threat of piracy; (2) the methods of protection employed to protect intellectual property in digital format; and (3) the importance of technological protection of intellectual property in electronic publications. The analysis is based on a sample of 23 UK electronic publishers. The interviews revealed an interesting assortment of protection methods and did not show that technological protection was a preferred way. Instead, the means of protection, in addition to copyright law, comprised niche markets, pricing, trust, bad publicity, and nontechnical and technical means.  相似文献   

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